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    Results: 1 to 20 of 397

    1.

    Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.

    Ilnytska O, Lyzogubov VV, Stevens MJ, Drel VR, Mashtalir N, Pacher P, Yorek MA, Obrosova IG.

    Diabetes. 2006 Jun;55(6):1686-94.PMID: 16731831 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.

    Drel VR, Pacher P, Vareniuk I, Pavlov I, Ilnytska O, Lyzogubov VV, Tibrewala J, Groves JT, Obrosova IG.

    Eur J Pharmacol. 2007 Aug 13;569(1-2):48-58. Epub 2007 Jun 9.PMID: 17644085 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.

    Drel VR, Pacher P, Vareniuk I, Pavlov IA, Ilnytska O, Lyzogubov VV, Bell SR, Groves JT, Obrosova IG.

    Int J Mol Med. 2007 Dec;20(6):783-92.PMID: 17982684 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.

    Obrosova IG, Drel VR, Oltman CL, Mashtalir N, Tibrewala J, Groves JT, Yorek MA.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1645-55. Epub 2007 Oct 2.PMID: 17911342 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.

    Li F, Szabó C, Pacher P, Southan GJ, Abatan OI, Charniauskaya T, Stevens MJ, Obrosova IG.

    Diabetologia. 2004 Apr;47(4):710-7.PMID: 15298348 [PubMed - indexed for MEDLINE]Related articles

    6.

    Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.

    Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA.

    Diabetes. 2005 Dec;54(12):3435-41.PMID: 16306359 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.

    Li F, Drel VR, Szabó C, Stevens MJ, Obrosova IG.

    Diabetes. 2005 May;54(5):1514-22.PMID: 15855340 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.

    Obrosova IG, Pacher P, Szabó C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA.

    Diabetes. 2005 Jan;54(1):234-42.PMID: 15616034 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of peripheral neuropathy in a streptozotocin-induced mouse model of diabetes.

    Vareniuk I, Pavlov IA, Obrosova IG.

    Diabetologia. 2008 Nov;51(11):2126-33. Epub 2008 Sep 19.PMID: 18802679 [PubMed - indexed for MEDLINE]Related articles

    10.

    Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

    Drel VR, Pacher P, Ali TK, Shin J, Julius U, El-Remessy AB, Obrosova IG.

    Int J Mol Med. 2008 Jun;21(6):667-76.PMID: 18506358 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats.

    Stevens MJ, Li F, Drel VR, Abatan OI, Kim H, Burnett D, Larkin D, Obrosova IG.

    J Pharmacol Exp Ther. 2007 Jan;320(1):458-64. Epub 2006 Oct 4.PMID: 17021258 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy.

    Obrosova IG, Xu W, Lyzogubov VV, Ilnytska O, Mashtalir N, Vareniuk I, Pavlov IA, Zhang J, Slusher B, Drel VR.

    Free Radic Biol Med. 2008 Mar 15;44(6):972-81. Epub 2007 Oct 3.PMID: 17976390 [PubMed - indexed for MEDLINE]Related articles

    13.

    Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.

    Drel VR, Xu W, Zhang J, Kador PF, Ali TK, Shin J, Julius U, Slusher B, El-Remessy AB, Obrosova IG.

    Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1778-90. Epub 2008 Dec 20.PMID: 19098320 [PubMed - indexed for MEDLINE]Related articles

    14.

    Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency.

    Vareniuk I, Pacher P, Pavlov IA, Drel VR, Obrosova IG.

    Int J Mol Med. 2009 May;23(5):571-80.PMID: 19360314 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy.

    Sharma SS, Kumar A, Kaundal RK.

    Life Sci. 2008 Mar 12;82(11-12):570-6. Epub 2007 Dec 26.PMID: 18262571 [PubMed - indexed for MEDLINE]Related articles

    16.

    Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

    Obrosova IG, Minchenko AG, Frank RN, Seigel GM, Zsengeller Z, Pacher P, Stevens MJ, Szabó C.

    Int J Mol Med. 2004 Jul;14(1):55-64.PMID: 15202016 [PubMed - indexed for MEDLINE]Related articles

    17.

    Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.

    Obrosova IG, Li F, Abatan OI, Forsell MA, Komjáti K, Pacher P, Szabó C, Stevens MJ.

    Diabetes. 2004 Mar;53(3):711-20.PMID: 14988256 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.

    Minchenko AG, Stevens MJ, White L, Abatan OI, Komjáti K, Pacher P, Szabó C, Obrosova IG.

    FASEB J. 2003 Aug;17(11):1514-6. Epub 2003 Jun 3.PMID: 12824290 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.

    Drel VR, Pacher P, Stevens MJ, Obrosova IG.

    Free Radic Biol Med. 2006 Apr 15;40(8):1454-65. Epub 2006 Jan 31.PMID: 16631535 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.

    Obrosova IG, Mabley JG, Zsengellér Z, Charniauskaya T, Abatan OI, Groves JT, Szabó C.

    FASEB J. 2005 Mar;19(3):401-3. Epub 2004 Dec 20.PMID: 15611153 [PubMed - indexed for MEDLINE]Related articlesFree article

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