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    Results: 1 to 20 of 209

    1.

    Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells.

    Yokoi T, Fukuo K, Yasuda O, Hotta M, Miyazaki J, Takemura Y, Kawamoto H, Ichijo H, Ogihara T.

    Diabetes. 2006 Jun;55(6):1660-5.PMID: 16731828 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Apoptosis signal-regulating kinase 1 in leukotriene D(4)-induced activator protein-1 activation in airway smooth muscle cells.

    Kumasawa F, Hashimoto S, Onose A, Jibiki I, Mizumura K, Matsumoto K, Maruoka S, Gon Y, Kobayashi T, Takahashi N, Ichijo H, Horie T.

    Eur J Pharmacol. 2005 Jul 4;517(1-2):11-6.PMID: 15970283 [PubMed - indexed for MEDLINE]Related articles

    3.

    Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells.

    Kim KS, Kang KW, Seu YB, Baek SH, Kim JR.

    Mech Ageing Dev. 2009 Mar;130(3):179-88. Epub 2008 Nov 21.PMID: 19071156 [PubMed - indexed for MEDLINE]Related articles

    4.

    Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes.

    Hayashi T, Matsui-Hirai H, Miyazaki-Akita A, Fukatsu A, Funami J, Ding QF, Kamalanathan S, Hattori Y, Ignarro LJ, Iguchi A.

    Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17018-23. Epub 2006 Oct 30.PMID: 17075048 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Induction of apoptosis signal-regulating Kinase 1 by E2F-1 may not be essential for E2F-1-mediated apoptosis in melanoma cells.

    Dong YB, Phelps AM, Yang HL, Jamshidi-Parsian A, Chen C, Hao H, Gomez-Gutierrez JG, Zhou HS, McMasters KM.

    Tumour Biol. 2007;28(2):111-22. Epub 2007 Feb 8.PMID: 17287612 [PubMed - indexed for MEDLINE]Related articles

    6.

    Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells.

    Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y.

    Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1634-9. Epub 2008 Jun 12.PMID: 18556572 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53.

    Chen J, Huang X, Halicka D, Brodsky S, Avram A, Eskander J, Bloomgarden NA, Darzynkiewicz Z, Goligorsky MS.

    Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1575-86. Epub 2005 Oct 21.PMID: 16243918 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy.

    Thandavarayan RA, Watanabe K, Ma M, Veeraveedu PT, Gurusamy N, Palaniyandi SS, Zhang S, Muslin AJ, Kodama M, Aizawa Y.

    Biochem Pharmacol. 2008 May 1;75(9):1797-806. Epub 2008 Feb 12.PMID: 18342293 [PubMed - indexed for MEDLINE]Related articles

    9.

    Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells.

    Wang L, Xing XP, Holmes A, Wadham C, Gamble JR, Vadas MA, Xia P.

    Circ Res. 2005 Oct 28;97(9):891-9. Epub 2005 Sep 22.PMID: 16179586 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Apoptosis signal-regulating kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency.

    Yamashita T, Yamamoto E, Kataoka K, Nakamura T, Matsuba S, Tokutomi Y, Dong YF, Ichijo H, Ogawa H, Kim-Mitsuyama S.

    Hypertension. 2007 Sep;50(3):519-24. Epub 2007 Jul 23.PMID: 17646574 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.

    Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.

    Gastroenterology. 2008 Oct;135(4):1311-21. Epub 2008 Jul 9.PMID: 18700144 [PubMed - indexed for MEDLINE]Related articles

    12.

    Olmesartan prevents cardiovascular injury and hepatic steatosis in obesity and diabetes, accompanied by apoptosis signal regulating kinase-1 inhibition.

    Yamamoto E, Dong YF, Kataoka K, Yamashita T, Tokutomi Y, Matsuba S, Ichijo H, Ogawa H, Kim-Mitsuyama S.

    Hypertension. 2008 Sep;52(3):573-80. Epub 2008 Aug 4.PMID: 18678790 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.

    Tan J, Zhuang L, Jiang X, Yang KK, Karuturi KM, Yu Q.

    J Biol Chem. 2006 Apr 14;281(15):10508-15. Epub 2006 Feb 13.PMID: 16476732 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis.

    Li X, Luo Y, Yu L, Lin Y, Luo D, Zhang H, He Y, Kim YO, Kim Y, Tang S, Min W.

    Cell Death Differ. 2008 Apr;15(4):739-50. Epub 2008 Jan 25.PMID: 18219322 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Important role of apoptosis signal-regulating kinase 1 in ischemia-induced angiogenesis.

    Izumi Y, Kim-Mitsuyama S, Yoshiyama M, Omura T, Shiota M, Matsuzawa A, Yukimura T, Murohara T, Takeya M, Ichijo H, Yoshikawa J, Iwao H.

    Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1877-83. Epub 2005 Jun 23.PMID: 15976330 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.

    Yamamoto E, Kataoka K, Shintaku H, Yamashita T, Tokutomi Y, Dong YF, Matsuba S, Ichijo H, Ogawa H, Kim-Mitsuyama S.

    Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2569-75. Epub 2007 Oct 11.PMID: 17932313 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    2-amino-phenoxazine-3-one attenuates glucose-induced augmentation of embryonic form of myosin heavy chain, endothelin-1 and plasminogen activator inhibitor-1 in human umbilical vein endothelial cells.

    Fukuda G, Yoshitake N, Khan ZA, Kanazawa M, Notoya Y, Che XF, Akiyama S, Tomoda A, Chakrabarti S, Odawara M.

    Biol Pharm Bull. 2005 May;28(5):797-801.PMID: 15863881 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    High glucose induces plasminogen activator inhibitor-1 expression through Rho/Rho-kinase-mediated NF-kappaB activation in bovine aortic endothelial cells.

    Iwasaki H, Okamoto R, Kato S, Konishi K, Mizutani H, Yamada N, Isaka N, Nakano T, Ito M.

    Atherosclerosis. 2008 Jan;196(1):22-8. Epub 2007 Feb 1.PMID: 17275007 [PubMed - indexed for MEDLINE]Related articles

    19.

    Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.

    Rikitake Y, Liao JK.

    Circulation. 2005 Jun 21;111(24):3261-8. Epub 2005 Jun 13.PMID: 15956119 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy.

    Kashiwase K, Higuchi Y, Hirotani S, Yamaguchi O, Hikoso S, Takeda T, Watanabe T, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Ueno H, Nishida K, Hori M, Otsu K.

    Biochem Biophys Res Commun. 2005 Feb 4;327(1):136-42.PMID: 15629441 [PubMed - indexed for MEDLINE]Related articles