PubMed

Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: reactive oxygen species may have a protective role in pancreatic beta-cells.

Li X, Chen H, Epstein PN.

Diabetes. 2006 Jun;55(6):1592-604.PMID: 16731821 [PubMed - indexed for MEDLINE]Related articlesFree article

MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity.

Chen H, Li X, Epstein PN.

Diabetes. 2005 May;54(5):1437-46.PMID: 15855331 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line.

Sigfrid LA, Cunningham JM, Beeharry N, Håkan Borg LA, Rosales Hernandez AL, Carlsson C, Bone AJ, Green IC.

J Mol Med. 2004 May;82(5):325-35. Epub 2004 Mar 9.PMID: 15007513 [PubMed - indexed for MEDLINE]Related articles

Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: a comparative study.

Cornelius JG, Luttge BG, Peck AB.

Free Radic Biol Med. 1993 Apr;14(4):409-20.PMID: 8468025 [PubMed - indexed for MEDLINE]Related articles

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes.

Augstein P, Elefanty AG, Allison J, Harrison LC.

Diabetologia. 1998 Nov;41(11):1381-8.PMID: 9833948 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells.

Horio F, Fukuda M, Katoh H, Petruzzelli M, Yano N, Rittershaus C, Bonner-Weir S, Hattori M.

Diabetologia. 1994 Jan;37(1):22-31.PMID: 8150225 [PubMed - indexed for MEDLINE]Related articles

Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.

Welsh N, Margulis B, Borg LA, Wiklund HJ, Saldeen J, Flodström M, Mello MA, Andersson A, Pipeleers DG, Hellerström C, et al.

Mol Med. 1995 Nov;1(7):806-20.PMID: 8612203 [PubMed - indexed for MEDLINE]Related articlesFree article

Ectopic PDX-1 expression in liver ameliorates type 1 diabetes.

Shternhall-Ron K, Quintana FJ, Perl S, Meivar-Levy I, Barshack I, Cohen IR, Ferber S.

J Autoimmun. 2007 Mar-May;28(2-3):134-42. Epub 2007 Mar 23.PMID: 17383157 [PubMed - indexed for MEDLINE]Related articles

Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species.

Tiedge M, Lortz S, Munday R, Lenzen S.

Diabetes. 1998 Oct;47(10):1578-85.PMID: 9753295 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.

Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, Lin-Shiau SY, Liu SH.

Diabetes. 2006 Jun;55(6):1614-24.PMID: 16731823 [PubMed - indexed for MEDLINE]Related articlesFree article

A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of streptozotocin in CBA/H mice.

Stosic-Grujicic S, Cvetkovic I, Mangano K, Fresta M, Maksimovic-Ivanic D, Harhaji L, Popadic D, Momcilovic M, Miljkovic D, Kim J, Al-Abed Y, Nicoletti F.

J Pharmacol Exp Ther. 2007 Mar;320(3):1038-49. Epub 2006 Dec 5. Erratum in: J Pharmacol Exp Ther. 2007 Apr;321(1):420. Abed, Yousef Al [corrected to Al-Abed, Yousef]. PMID: 17148780 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of catalase provides partial protection to transgenic mouse beta cells.

Xu B, Moritz JT, Epstein PN.

Free Radic Biol Med. 1999 Oct;27(7-8):830-7.PMID: 10515587 [PubMed - indexed for MEDLINE]Related articles

Calcitonin gene-related peptide gene therapy suppresses reactive oxygen species in the pancreas and prevents mice from autoimmune diabetes.

She F, Sun W, Mao JM, Wang X.

Sheng Li Xue Bao. 2003 Dec 25;55(6):625-32.PMID: 14695477 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effect of Astragalus polysaccharide on pancreatic cell mass in type 1 diabetic mice]

Li RJ, Qiu SD, Chen HX, Tian H, Liu GQ.

Zhongguo Zhong Yao Za Zhi. 2007 Oct;32(20):2169-73. Chinese. PMID: 18306755 [PubMed - indexed for MEDLINE]Related articles

Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.

Hägerkvist R, Sandler S, Mokhtari D, Welsh N.

FASEB J. 2007 Feb;21(2):618-28. Epub 2006 Nov 29.PMID: 17135364 [PubMed - indexed for MEDLINE]Related articlesFree article

A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, hypoglycemia, and significant resistance to experimental diabetes.

Robertson K, Lu Y, De Jesus K, Li B, Su Q, Lund PK, Liu JL.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E928-38. Epub 2008 Feb 12.PMID: 18270301 [PubMed - indexed for MEDLINE]Related articlesFree article

Newly weaned nonobese diabetic mice show heightened early diabetes sensitivity to multiple low doses of streptozotocin than nondiabetes-prone CD-1 mice: initial beta-cell damage a key trigger for type 1 diabetes?

Reddy S, Elliott RB, Chang M, Hsu T, Rodrigues JA, Qiao L, Robinson E.

Pancreas. 2008 Jul;37(1):e8-e19.PMID: 18580436 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes.

Hotta M, Tashiro F, Ikegami H, Niwa H, Ogihara T, Yodoi J, Miyazaki J.

J Exp Med. 1998 Oct 19;188(8):1445-51.PMID: 9782121 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotinamide prevents the development of diabetes in the cyclophosphamide-induced NOD mouse model by reducing beta-cell apoptosis.

O'Brien BA, Harmon BV, Cameron DP, Allan DJ.

J Pathol. 2000 May;191(1):86-92.PMID: 10767724 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.

Gurgul E, Lortz S, Tiedge M, Jörns A, Lenzen S.

Diabetes. 2004 Sep;53(9):2271-80.PMID: 15331536 [PubMed - indexed for MEDLINE]Related articlesFree article