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    Results: 1 to 20 of 364

    1.

    Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.

    Martinez SC, Cras-Méneur C, Bernal-Mizrachi E, Permutt MA.

    Diabetes. 2006 Jun;55(6):1581-91.PMID: 16731820 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.

    Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.

    J Biol Chem. 2005 Jun 10;280(23):22297-307. Epub 2005 Apr 6.PMID: 15817464 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.

    Ohsugi M, Cras-Méneur C, Zhou Y, Bernal-Mizrachi E, Johnson JD, Luciani DS, Polonsky KS, Permutt MA.

    J Biol Chem. 2005 Feb 11;280(6):4992-5003. Epub 2004 Nov 15.PMID: 15546857 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

    Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.

    Diabetes. 2008 Apr;57(4):846-59. Epub 2008 Jan 3.PMID: 18174526 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.

    Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, Lin-Shiau SY, Liu SH.

    Diabetes. 2006 Jun;55(6):1614-24.PMID: 16731823 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Forkhead transcription factor FoxO1 transduces insulin-like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells.

    Machida S, Spangenburg EE, Booth FW.

    J Cell Physiol. 2003 Sep;196(3):523-31.PMID: 12891709 [PubMed - indexed for MEDLINE]Related articles

    7.

    Bidirectional regulation of upstream IGF-I/insulin receptor signaling and downstream FOXO1 in cardiomyocytes.

    Liu TJ, Lai HC, Ting CT, Wang PH.

    J Endocrinol. 2007 Jan;192(1):149-58.PMID: 17210752 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Prostaglandin E2 regulates Foxo activity via the Akt pathway: implications for pancreatic islet beta cell dysfunction.

    Meng ZX, Sun JX, Ling JJ, Lv JH, Zhu DY, Chen Q, Sun YJ, Han X.

    Diabetologia. 2006 Dec;49(12):2959-68. Epub 2006 Oct 11.PMID: 17033838 [PubMed - indexed for MEDLINE]Related articles

    9.

    Characterization of insulin inhibition of transactivation by a C-terminal fragment of the forkhead transcription factor Foxo1 in rat hepatoma cells.

    Perrot V, Rechler MM.

    J Biol Chem. 2003 Jul 11;278(28):26111-9. Epub 2003 Apr 29.PMID: 12724332 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    B cell receptor signaling down-regulates forkhead box transcription factor class O 1 mRNA expression via phosphatidylinositol 3-kinase and Bruton's tyrosine kinase.

    Hinman RM, Bushanam JN, Nichols WA, Satterthwaite AB.

    J Immunol. 2007 Jan 15;178(2):740-7.PMID: 17202334 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Glucose promotes pancreatic islet beta-cell survival through a PI 3-kinase/Akt-signaling pathway.

    Srinivasan S, Bernal-Mizrachi E, Ohsugi M, Permutt MA.

    Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E784-93.PMID: 12217896 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction.

    Zhang X, Yong W, Lv J, Zhu Y, Zhang J, Chen F, Zhang R, Yang T, Sun Y, Han X.

    Endocrinology. 2009 Sep;150(9):4065-73. Epub 2009 May 14.PMID: 19443572 [PubMed - indexed for MEDLINE]Related articles

    13.

    The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells.

    Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D, Brenner DA.

    Gastroenterology. 2007 Apr;132(4):1434-46. Epub 2007 Jan 25.PMID: 17408630 [PubMed - indexed for MEDLINE]Related articles

    14.

    Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion.

    Tsai WC, Bhattacharyya N, Han LY, Hanover JA, Rechler MM.

    Endocrinology. 2003 Dec;144(12):5615-22. Epub 2003 Sep 18.PMID: 14500580 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes.

    Ohsugi M, Cras-Méneur C, Zhou Y, Warren W, Bernal-Mizrachi E, Permutt MA.

    Diabetes. 2004 Jun;53(6):1496-508.PMID: 15161754 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Pancreatic glucokinase is activated by insulin-like growth factor-I.

    Yoshida K, Murao K, Imachi H, Cao WM, Yu X, Li J, Ahmed RA, Kitanaka N, Wong NC, Unterman TG, Magnuson MA, Ishida T.

    Endocrinology. 2007 Jun;148(6):2904-13. Epub 2007 Feb 22.PMID: 17317782 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases.

    Ni YG, Wang N, Cao DJ, Sachan N, Morris DJ, Gerard RD, Kuro-O M, Rothermel BA, Hill JA.

    Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20517-22. Epub 2007 Dec 12.PMID: 18077353 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.

    Gan L, Zheng W, Chabot JG, Unterman TG, Quirion R.

    J Neurochem. 2005 Jun;93(5):1209-19.PMID: 15934941 [PubMed - indexed for MEDLINE]Related articles

    19.

    Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway.

    Latres E, Amini AR, Amini AA, Griffiths J, Martin FJ, Wei Y, Lin HC, Yancopoulos GD, Glass DJ.

    J Biol Chem. 2005 Jan 28;280(4):2737-44. Epub 2004 Nov 17.PMID: 15550386 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors.

    Terragni J, Graham JR, Adams KW, Schaffer ME, Tullai JW, Cooper GM.

    BMC Cell Biol. 2008 Jan 28;9:6.PMID: 18226221 [PubMed - indexed for MEDLINE]Related articlesFree article

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