PubMed

Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle.

Mas A, Montané J, Anguela XM, Muñoz S, Douar AM, Riu E, Otaegui P, Bosch F.

Diabetes. 2006 Jun;55(6):1546-53.PMID: 16731816 [PubMed - indexed for MEDLINE]Related articlesFree article

Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: insights from transgenic mice.

Riu E, Mas A, Ferre T, Pujol A, Gros L, Otaegui P, Montoliu L, Bosch F.

Diabetes. 2002 Mar;51(3):704-11.PMID: 11872670 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of glucokinase in skeletal muscle: a new approach to counteract diabetic hyperglycemia.

Otaegui PJ, Ferre T, Pujol A, Riu E, Jimenez R, Bosch F.

Hum Gene Ther. 2000 Jul 20;11(11):1543-52.PMID: 10945768 [PubMed - indexed for MEDLINE]Related articles

Glucose-regulated glucose uptake by transplanted muscle cells expressing glucokinase counteracts diabetic hyperglycemia.

Otaegui PJ, Ontiveros M, Ferre T, Riu E, Jiménez R, Bosch F.

Hum Gene Ther. 2002 Dec 10;13(18):2125-33.PMID: 12542844 [PubMed - indexed for MEDLINE]Related articles

Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo.

Jiménez-Chillarón JC, Newgard CB, Gómez-Foix AM.

FASEB J. 1999 Dec;13(15):2153-60.PMID: 10593862 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase gene transfer to skeletal muscle of diabetic Zucker fatty rats improves insulin-sensitive glucose uptake.

Jiménez-Chillarón JC, Telemaque-Potts S, Gómez-Valadés AG, Anderson P, Newgard CB, Gómez-Foix AM.

Metabolism. 2002 Jan;51(1):121-6.PMID: 11782883 [PubMed - indexed for MEDLINE]Related articles

Correction of diabetic alterations by glucokinase.

Ferre T, Pujol A, Riu E, Bosch F, Valera A.

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7225-30.PMID: 8692973 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes.

Morral N, McEvoy R, Dong H, Meseck M, Altomonte J, Thung S, Woo SL.

Hum Gene Ther. 2002 Sep 1;13(13):1561-70.PMID: 12228011 [PubMed - indexed for MEDLINE]Related articles

Prevention of obesity and insulin resistance by glucokinase expression in skeletal muscle of transgenic mice.

Otaegui PJ, Ferre T, Riu E, Bosch F.

FASEB J. 2003 Nov;17(14):2097-9. Epub 2003 Sep 18.PMID: 14500548 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT4 in skeletal muscle.

Leturque A, Loizeau M, Vaulont S, Salminen M, Girard J.

Diabetes. 1996 Jan;45(1):23-7.PMID: 8522055 [PubMed - indexed for MEDLINE]Related articles

Expression of glucokinase in cultured human muscle cells confers insulin-independent and glucose concentration-dependent increases in glucose disposal and storage.

Baqué S, Montell E, Guinovart JJ, Newgard CB, Gómez-Foix AM.

Diabetes. 1998 Sep;47(9):1392-8.PMID: 9726226 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotypic correction of diabetic mice by adenovirus-mediated glucokinase expression.

Desai UJ, Slosberg ED, Boettcher BR, Caplan SL, Fanelli B, Stephan Z, Gunther VJ, Kaleko M, Connelly S.

Diabetes. 2001 Oct;50(10):2287-95.PMID: 11574410 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, Kim JH, Sumner AD, Vary TC, Gardner TW, Bronson SK, Kim JK.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1687-96. Epub 2007 Oct 2.PMID: 17911348 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene therapy of streptozotocin-induced diabetes by intramuscular delivery of modified preproinsulin genes.

Croze F, Prud'homme GJ.

J Gene Med. 2003 May;5(5):425-37.PMID: 12731091 [PubMed - indexed for MEDLINE]Related articles

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele.

Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S.

Am J Physiol. 1997 Oct;273(4 Pt 1):E743-50.PMID: 9357804 [PubMed - indexed for MEDLINE]Related articlesFree article

Engineered enteroendocrine cells secrete insulin in response to glucose and reverse hyperglycemia in diabetic mice.

Han J, Lee HH, Kwon H, Shin S, Yoon JW, Jun HS.

Mol Ther. 2007 Jun;15(6):1195-202. Epub 2007 Feb 13.PMID: 17299398 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of adeno-associated viral vector-mediated insulin gene transfer via portal vein to the livers of streptozotocin-induced diabetic Sprague-Dawley rats.

Park YM, Woo S, Lee GT, Ko JY, Lee Y, Zhao ZS, Kim HJ, Ahn CW, Cha BS, Kim KS, Park CW, Lee HC.

J Gene Med. 2005 May;7(5):621-9.PMID: 15651056 [PubMed - indexed for MEDLINE]Related articles

Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin production reduces hyperglycemia in diabetic mice.

Burkhardt BR, Parker MJ, Zhang YC, Song S, Wasserfall CH, Atkinson MA.

FEBS Lett. 2005 Oct 24;579(25):5759-64. Epub 2005 Oct 5.PMID: 16223491 [PubMed - indexed for MEDLINE]Related articles

Inhibition of pancreatic beta-cell glucokinase by antisense RNA expression in transgenic mice: mouse strain-dependent alteration of glucose tolerance.

Ishihara H, Tashiro F, Ikuta K, Asano T, Katagiri H, Inukai K, Kikuchi M, Yazaki Y, Oka Y, Miyazaki J.

FEBS Lett. 1995 Sep 11;371(3):329-32.PMID: 7556622 [PubMed - indexed for MEDLINE]Related articles

Effect of polyethylenimine on recombinant adeno-associated virus mediated insulin gene therapy.

Hsu PY, Yang YW.

J Gene Med. 2005 Oct;7(10):1311-21.PMID: 15906397 [PubMed - indexed for MEDLINE]Related articles