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Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men.

Gable DR, Stephens JW, Cooper JA, Miller GJ, Humphries SE.

Diabetes. 2006 May;55(5):1504-11.PMID: 16644712 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

Hsu YH, Niu T, Song Y, Tinker L, Kuller LH, Liu S.

Diabetes. 2008 Apr;57(4):1101-7. Epub 2008 Jan 25.PMID: 18223008 [PubMed - indexed for MEDLINE]Related articlesFree article

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.

Bulotta A, Ludovico O, Coco A, Di Paola R, Quattrone A, Carella M, Pellegrini F, Prudente S, Trischitta V.

J Clin Endocrinol Metab. 2005 Feb;90(2):1176-80. Epub 2004 Nov 23.PMID: 15562023 [PubMed - indexed for MEDLINE]Related articlesFree article

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

D'Adamo M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R, Perticone F, Folli F, Sesti G.

Diabetes. 2004 Jul;53(7):1905-10.PMID: 15220218 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.

Rudofsky G Jr, Schroedter A, Schlotterer A, Voron'ko OE, Schlimme M, Tafel J, Isermann BH, Humpert PM, Morcos M, Bierhaus A, Nawroth PP, Hamann A.

Diabetes Care. 2006 Jan;29(1):89-94.PMID: 16373902 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.

Wang H, Chu WS, Lu T, Hasstedt SJ, Kern PA, Elbein SC.

Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E1-7. Epub 2003 Aug 12.PMID: 12915397 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

Krempler F, Esterbauer H, Weitgasser R, Ebenbichler C, Patsch JR, Miller K, Xie M, Linnemayr V, Oberkofler H, Patsch W.

Diabetes. 2002 Nov;51(11):3331-5.PMID: 12401727 [PubMed - indexed for MEDLINE]Related articlesFree article

A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes.

Reis AF, Dubois-Laforgue D, Bellanné-Chantelot C, Timsit J, Velho G.

Mol Genet Metab. 2004 Aug;82(4):339-44.PMID: 15308133 [PubMed - indexed for MEDLINE]Related articles

Effects of UCP2 and UCP3 variants on the manifestation of overweight in Korean children.

Jun HS, Kim IK, Lee HJ, Lee HJ, Kang JH, Kim JR, Shin HD, Song J.

Obesity (Silver Spring). 2009 Feb;17(2):355-62. Epub 2008 Nov 27.PMID: 19039313 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2.

Dhamrait SS, Stephens JW, Cooper JA, Acharya J, Mani AR, Moore K, Miller GJ, Humphries SE, Hurel SJ, Montgomery HE.

Eur Heart J. 2004 Mar;25(6):468-75.PMID: 15039126 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP, Easlick J, Warden CH, Pecqueur C, Raimbault S, Ricquier D, Silver MH, Shuldiner AR, Solanes G, Lowell BB, Chung WK, Leibel RL, Pratley R, Ravussin E.

Hum Mol Genet. 1998 Sep;7(9):1431-5.PMID: 9700198 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study.

Salopuro T, Pulkkinen L, Lindström J, Kolehmainen M, Tolppanen AM, Eriksson JG, Valle TT, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M.

BMC Med Genet. 2009 Sep 21;10:94.PMID: 19769793 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.

Kovacs P, Ma L, Hanson RL, Franks P, Stumvoll M, Bogardus C, Baier LJ.

Diabetologia. 2005 Nov;48(11):2292-5. Epub 2005 Sep 16.PMID: 16167150 [PubMed - indexed for MEDLINE]Related articles

Linkage exclusion analysis of two candidate regions on chromosomes 7 and 11: leptin and UCP2/UCP3 are not QTLs for obesity in US Caucasians.

Guo JJ, Liu YJ, Li MX, Yang YJ, Recker RR, Deng HW.

Biochem Biophys Res Commun. 2005 Jul 1;332(2):602-8.PMID: 15910756 [PubMed - indexed for MEDLINE]Related articles

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study.

Yu X, Jacobs DR Jr, Schreiner PJ, Gross MD, Steffes MW, Fornage M.

Clin Chem. 2005 Aug;51(8):1451-6. Epub 2005 Jun 10.PMID: 15951317 [PubMed - indexed for MEDLINE]Related articlesFree article

[Common variants in beta 3-adrenergic-receptor and uncoupling protein-2 genes are associated with type 2 diabetes and obesity]

Xiu LL, Weng JP, Sui Y, Wang J, Yan JH, Huang ZM.

Zhonghua Yi Xue Za Zhi. 2004 Mar 2;84(5):375-9. Chinese. PMID: 15061987 [PubMed - indexed for MEDLINE]Related articles

Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.

Halsall DJ, Luan J, Saker P, Huxtable S, Farooqi IS, Keogh J, Wareham NJ, O'Rahilly S.

Int J Obes Relat Metab Disord. 2001 Apr;25(4):472-7.PMID: 11319649 [PubMed - indexed for MEDLINE]Related articles

An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort.

Meirhaeghe A, Amouyel P, Helbecque N, Cottel D, Otabe S, Froguel P, Vasseur F.

Diabetologia. 2000 Nov;43(11):1424-8.PMID: 11126413 [PubMed - indexed for MEDLINE]Related articles

The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men.

Cheurfa N, Dubois-Laforgue D, Ferrarezi DA, Reis AF, Brenner GM, Bouché C, Le Feuvre C, Fumeron F, Timsit J, Marre M, Velho G.

Diabetes. 2008 Apr;57(4):1063-8. Epub 2008 Jan 11.PMID: 18192542 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients.

Sasahara M, Nishi M, Kawashima H, Ueda K, Sakagashira S, Furuta H, Matsumoto E, Hanabusa T, Sasaki H, Nanjo K.

Diabetes. 2004 Feb;53(2):482-5.PMID: 14747301 [PubMed - indexed for MEDLINE]Related articlesFree article