PubMed

Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives.

Sapone A, de Magistris L, Pietzak M, Clemente MG, Tripathi A, Cucca F, Lampis R, Kryszak D, Cartenì M, Generoso M, Iafusco D, Prisco F, Laghi F, Riegler G, Carratu R, Counts D, Fasano A.

Diabetes. 2006 May;55(5):1443-9.PMID: 16644703 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.

Watts T, Berti I, Sapone A, Gerarduzzi T, Not T, Zielke R, Fasano A.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2916-21. Epub 2005 Feb 14.PMID: 15710870 [PubMed - indexed for MEDLINE]Related articlesFree article

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Tripathi A, Sapone A, Thakar M, Iacono G, Carroccio A, D'Agate C, Not T, Zampini L, Catassi C, Fasano A.

Scand J Gastroenterol. 2006 Apr;41(4):408-19.PMID: 16635908 [PubMed - indexed for MEDLINE]Related articles

Leaking gut in type 1 diabetes.

Vaarala O.

Curr Opin Gastroenterol. 2008 Nov;24(6):701-6. Review.PMID: 19122519 [PubMed - indexed for MEDLINE]Related articles

Permeability, zonulin production, and enteropathy in dermatitis herpetiformis.

Smecuol E, Sugai E, Niveloni S, Vázquez H, Pedreira S, Mazure R, Moreno ML, Label M, Mauriño E, Fasano A, Meddings J, Bai JC.

Clin Gastroenterol Hepatol. 2005 Apr;3(4):335-41.PMID: 15822038 [PubMed - indexed for MEDLINE]Related articles

Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease.

Fasano A, Not T, Wang W, Uzzau S, Berti I, Tommasini A, Goldblum SE.

Lancet. 2000 Apr 29;355(9214):1518-9.PMID: 10801176 [PubMed - indexed for MEDLINE]Related articles

Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall.

Fasano A.

Am J Pathol. 2008 Nov;173(5):1243-52. Epub 2008 Oct 2.PMID: 18832585 [PubMed - indexed for MEDLINE]Related articlesFree article

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.

Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A.

Gastroenterology. 2008 Jul;135(1):194-204.e3. Epub 2008 Mar 21.PMID: 18485912 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes.

Neu J, Reverte CM, Mackey AD, Liboni K, Tuhacek-Tenace LM, Hatch M, Li N, Caicedo RA, Schatz DA, Atkinson M.

J Pediatr Gastroenterol Nutr. 2005 May;40(5):589-95.PMID: 15861021 [PubMed - indexed for MEDLINE]Related articles

Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure.

El Asmar R, Panigrahi P, Bamford P, Berti I, Not T, Coppa GV, Catassi C, Fasano A.

Gastroenterology. 2002 Nov;123(5):1607-15. Erratum in: Gastroenterology 2003 Jan;124(1):275. El Asmar Rahzi [corrected to El Asmar Ramzi]. PMID: 12404235 [PubMed - indexed for MEDLINE]Related articles

Increased intestinal permeability precedes clinical onset of type 1 diabetes.

Bosi E, Molteni L, Radaelli MG, Folini L, Fermo I, Bazzigaluppi E, Piemonti L, Pastore MR, Paroni R.

Diabetologia. 2006 Dec;49(12):2824-7. Epub 2006 Oct 7.PMID: 17028899 [PubMed - indexed for MEDLINE]Related articles

Association of MYO9B haplotype with type 1 diabetes.

Santiago JL, Martínez A, Núñez C, de la Calle H, Fernández-Arquero M, de la Concha EG, Urcelay E.

Hum Immunol. 2008 Feb;69(2):112-5. Epub 2008 Feb 11.PMID: 18361936 [PubMed - indexed for MEDLINE]Related articles

Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat.

Meddings JB, Jarand J, Urbanski SJ, Hardin J, Gall DG.

Am J Physiol. 1999 Apr;276(4 Pt 1):G951-7.PMID: 10198339 [PubMed - indexed for MEDLINE]Related articlesFree article

The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.

Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C, Cossu E, Pozzilli P, Falorni A, Buzzetti R; NIRAD Study Group.

Diabetes Care. 2008 Mar;31(3):534-8. Epub 2007 Dec 4.PMID: 18056891 [PubMed - indexed for MEDLINE]Related articlesFree article

Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function.

Clemente MG, De Virgiliis S, Kang JS, Macatagney R, Musu MP, Di Pierro MR, Drago S, Congia M, Fasano A.

Gut. 2003 Feb;52(2):218-23.PMID: 12524403 [PubMed - indexed for MEDLINE]Related articlesFree article

The measurement and clinical significance of intestinal permeability.

Teshima CW, Meddings JB.

Curr Gastroenterol Rep. 2008 Oct;10(5):443-9. Review.PMID: 18799118 [PubMed - indexed for MEDLINE]Related articles

A type 1 diabetes subgroup with a female bias is characterised by failure in tolerance to thyroid peroxidase at an early age and a strong association with the cytotoxic T-lymphocyte-associated antigen-4 gene.

Howson JM, Dunger DB, Nutland S, Stevens H, Wicker LS, Todd JA.

Diabetologia. 2007 Apr;50(4):741-6. Epub 2007 Feb 14.PMID: 17334650 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.

Tsurumaru M, Kawasaki E, Ida H, Migita K, Moriuchi A, Fukushima K, Fukushima T, Abiru N, Yamasaki H, Noso S, Ikegami H, Awata T, Sasaki H, Eguchi K.

J Clin Endocrinol Metab. 2006 Aug;91(8):3138-43. Epub 2006 May 30.PMID: 16735488 [PubMed - indexed for MEDLINE]Related articlesFree article

Intestinal permeability and diabetes mellitus type 2.

Secondulfo M, de Magistris L, Sapone A, Di Monda G, Esposito P, Carratù R.

Minerva Gastroenterol Dietol. 1999 Sep;45(3):187-92. English, Italian. PMID: 16498329 [PubMed]Related articles

HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients.

Cejkova P, Novota P, Cerna M, Kolostova K, Novakova D, Kucera P, Novak J, Andel M, Weber P, Zdarsky E.

Int J Immunogenet. 2008 Apr;35(2):133-40. Epub 2008 Feb 11.PMID: 18279373 [PubMed - indexed for MEDLINE]Related articles