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    Results: 1 to 20 of 200

    1.

    Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance.

    Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY.

    Diabetes. 2006 May;55(5):1421-9.PMID: 16644700 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

    Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY.

    Diabetes. 2007 Oct;56(10):2579-88. Epub 2007 Jul 16.PMID: 17639022 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Regulation of insulin exocytosis by Munc13-1.

    Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY.

    J Biol Chem. 2003 Jul 25;278(30):27556-63. Epub 2003 May 13.PMID: 12871971 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Munc13-1 is required for the sustained release of insulin from pancreatic beta cells.

    Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T.

    Cell Metab. 2006 Jun;3(6):463-8. Epub 2006 May 11.PMID: 16697276 [PubMed - indexed for MEDLINE]Related articles

    5.

    Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice.

    Wang XP, Norman MA, Yang J, Cheung A, Moldovan S, Demayo FJ, Brunicardi FC.

    Surgery. 2004 Sep;136(3):585-92.PMID: 15349106 [PubMed - indexed for MEDLINE]Related articles

    6.

    CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.

    Wierup N, Richards WG, Bannon AW, Kuhar MJ, Ahrén B, Sundler F.

    Regul Pept. 2005 Jul 15;129(1-3):203-11.PMID: 15927717 [PubMed - indexed for MEDLINE]Related articles

    7.

    Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance.

    Dai C, Huh CG, Thorgeirsson SS, Liu Y.

    Am J Pathol. 2005 Aug;167(2):429-36.PMID: 16049329 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion.

    Marshall BA, Tordjman K, Host HH, Ensor NJ, Kwon G, Marshall CA, Coleman T, McDaniel ML, Semenkovich CF.

    J Biol Chem. 1999 Sep 24;274(39):27426-32.PMID: 10488074 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.

    Olofsson CS, Håkansson J, Salehi A, Bengtsson M, Galvanovskis J, Partridge C, SörhedeWinzell M, Xian X, Eliasson L, Lundquist I, Semb H, Rorsman P.

    Endocrinology. 2009 Jul;150(7):3067-75. Epub 2009 Feb 12.PMID: 19213846 [PubMed - indexed for MEDLINE]Related articles

    10.

    Transgenic mouse overexpressing syntaxin-1A as a diabetes model.

    Lam PP, Leung YM, Sheu L, Ellis J, Tsushima RG, Osborne LR, Gaisano HY.

    Diabetes. 2005 Sep;54(9):2744-54.PMID: 16123365 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice.

    Gorogawa S, Fujitani Y, Kaneto H, Hazama Y, Watada H, Miyamoto Y, Takeda K, Akira S, Magnuson MA, Yamasaki Y, Kajimoto Y, Hori M.

    Biochem Biophys Res Commun. 2004 Jul 9;319(4):1159-70.PMID: 15194489 [PubMed - indexed for MEDLINE]Related articles

    12.

    Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance.

    Oh E, Spurlin BA, Pessin JE, Thurmond DC.

    Diabetes. 2005 Mar;54(3):638-47.PMID: 15734838 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion.

    Fujino T, Asaba H, Kang MJ, Ikeda Y, Sone H, Takada S, Kim DH, Ioka RX, Ono M, Tomoyori H, Okubo M, Murase T, Kamataki A, Yamamoto J, Magoori K, Takahashi S, Miyamoto Y, Oishi H, Nose M, Okazaki M, Usui S, Imaizumi K, Yanagisawa M, Sakai J, Yamamoto TT.

    Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):229-34. Epub 2002 Dec 30.PMID: 12509515 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis.

    Cooksey RC, Jouihan HA, Ajioka RS, Hazel MW, Jones DL, Kushner JP, McClain DA.

    Endocrinology. 2004 Nov;145(11):5305-12. Epub 2004 Aug 12.PMID: 15308612 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

    Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

    Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

    16.

    A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

    Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD.

    Diabetologia. 2005 Apr;48(4):675-86. Epub 2005 Feb 24.PMID: 15729571 [PubMed - indexed for MEDLINE]Related articles

    17.

    Inhibition of Ca2+-independent phospholipase A2 results in insufficient insulin secretion and impaired glucose tolerance.

    Song K, Zhang X, Zhao C, Ang NT, Ma ZA.

    Mol Endocrinol. 2005 Feb;19(2):504-15. Epub 2004 Oct 7.PMID: 15471944 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice.

    Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA.

    Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E157-67. Epub 2007 Oct 30.PMID: 17971510 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

    Latour MG, Alquier T, Oseid E, Tremblay C, Jetton TL, Luo J, Lin DC, Poitout V.

    Diabetes. 2007 Apr;56(4):1087-94.PMID: 17395749 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.

    Roduit R, Masiello P, Wang SP, Li H, Mitchell GA, Prentki M.

    Diabetes. 2001 Sep;50(9):1970-5.PMID: 11522661 [PubMed - indexed for MEDLINE]Related articlesFree article

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