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    Results: 1 to 20 of 129

    1.

    Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4.

    Ranta F, Avram D, Berchtold S, Düfer M, Drews G, Lang F, Ullrich S.

    Diabetes. 2006 May;55(5):1380-90.PMID: 16644695 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.

    Winzell MS, Ahrén B.

    J Mol Endocrinol. 2008 Feb;40(2):93-100.PMID: 18234911 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.

    Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.

    Diabetes. 2008 May;57(5):1205-15. Epub 2008 Feb 5.PMID: 18252896 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation.

    Avram D, Ranta F, Hennige AM, Berchtold S, Hopp S, Häring HU, Lang F, Ullrich S.

    Cell Physiol Biochem. 2008;21(5-6):455-62. Epub 2008 Apr 24.PMID: 18453753 [PubMed - indexed for MEDLINE]Related articles

    5.

    Regulation of calcineurin activity in insulin-secreting cells: stimulation by Hsp90 during glucocorticoid-induced apoptosis.

    Ranta F, Düfer M, Stork B, Wesselborg S, Drews G, Häring HU, Lang F, Ullrich S.

    Cell Signal. 2008 Oct;20(10):1780-6. Epub 2008 Jun 18.PMID: 18611438 [PubMed - indexed for MEDLINE]Related articles

    6.

    Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion.

    Ullrich S, Berchtold S, Ranta F, Seebohm G, Henke G, Lupescu A, Mack AF, Chao CM, Su J, Nitschke R, Alexander D, Friedrich B, Wulff P, Kuhl D, Lang F.

    Diabetes. 2005 Apr;54(4):1090-9.PMID: 15793248 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells.

    Kang G, Chepurny OG, Holz GG.

    J Physiol. 2001 Oct 15;536(Pt 2):375-85.PMID: 11600673 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Dexamethasone suppresses phospholipase C activation and insulin secretion from isolated rat islets.

    Zawalich WS, Tesz GJ, Yamazaki H, Zawalich KC, Philbrick W.

    Metabolism. 2006 Jan;55(1):35-42.PMID: 16324917 [PubMed - indexed for MEDLINE]Related articles

    9.

    Glucocorticoids protect against apoptosis induced by serum deprivation, cyclic adenosine 3',5'-monophosphate and p53 activation in immortalized human granulosa cells: involvement of Bcl-2.

    Sasson R, Tajima K, Amsterdam A.

    Endocrinology. 2001 Feb;142(2):802-11.PMID: 11159853 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.

    Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I.

    J Endocrinol. 2007 Apr;193(1):65-74.PMID: 17400804 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

    Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

    Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.PMID: 18162507 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Anti-apoptotic action of exendin-4 in INS-1 beta cells: comparative protein pattern analysis of isolated mitochondria.

    Tews D, Lehr S, Hartwig S, Osmers A, Paslack W, Eckel J.

    Horm Metab Res. 2009 Apr;41(4):294-301. Epub 2008 Dec 15.PMID: 19085810 [PubMed - indexed for MEDLINE]Related articles

    13.

    Exendin-4 and exercise promotes beta-cell function and mass through IRS2 induction in islets of diabetic rats.

    Park S, Hong SM, Sung SR.

    Life Sci. 2008 Feb 27;82(9-10):503-11. Epub 2007 Dec 31.PMID: 18237751 [PubMed - indexed for MEDLINE]Related articles

    14.

    Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs.

    D'Amico E, Hui H, Khoury N, Di Mario U, Perfetti R.

    J Mol Endocrinol. 2005 Apr;34(2):377-90.PMID: 15821104 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Genistein acutely stimulates insulin secretion in pancreatic beta-cells through a cAMP-dependent protein kinase pathway.

    Liu D, Zhen W, Yang Z, Carter JD, Si H, Reynolds KA.

    Diabetes. 2006 Apr;55(4):1043-50.PMID: 16567527 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.

    Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A.

    Diabetes. 2008 Apr;57(4):938-44. Epub 2008 Jan 2.PMID: 18171713 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

    Ní Chonghaile T, Concannon CG, Szegezdi E, Gorman AM, Samali A.

    Apoptosis. 2006 Jul;11(7):1247-55.PMID: 16699951 [PubMed - indexed for MEDLINE]Related articles

    18.

    Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells.

    Cao X, Gao Z, Robert CE, Greene S, Xu G, Xu W, Bell E, Campbell D, Zhu Y, Young R, Trucco M, Markmann JF, Naji A, Wolf BA.

    Diabetes. 2003 Sep;52(9):2296-303.PMID: 12941769 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells.

    Sherry NA, Chen W, Kushner JA, Glandt M, Tang Q, Tsai S, Santamaria P, Bluestone JA, Brillantes AM, Herold KC.

    Endocrinology. 2007 Nov;148(11):5136-44. Epub 2007 Aug 2.PMID: 17673522 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.

    Conradie MM, de Wet H, Kotze DD, Burrin JM, Hough FS, Hulley PA.

    J Endocrinol. 2007 Nov;195(2):229-40.PMID: 17951534 [PubMed - indexed for MEDLINE]Related articlesFree article

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