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    Results: 1 to 20 of 264

    1.

    Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine.

    Federico LM, Naples M, Taylor D, Adeli K.

    Diabetes. 2006 May;55(5):1316-26.PMID: 16644688 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction.

    Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K.

    J Biol Chem. 2002 Aug 30;277(35):31646-55. Epub 2002 Jun 17.PMID: 12070142 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins.

    Qin B, Qiu W, Avramoglu RK, Adeli K.

    Diabetes. 2007 Feb;56(2):450-61.PMID: 17259391 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids.

    Guo Q, Avramoglu RK, Adeli K.

    Metabolism. 2005 May;54(5):689-97.PMID: 15877301 [PubMed - indexed for MEDLINE]Related articles

    5.

    Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.

    Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K.

    J Biol Chem. 2002 Jan 4;277(1):793-803. Epub 2001 Oct 11.PMID: 11598116 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster.

    Lewis GF, Uffelman K, Naples M, Szeto L, Haidari M, Adeli K.

    Endocrinology. 2005 Jan;146(1):247-55. Epub 2004 Oct 14.PMID: 15486228 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes.

    Qin B, Dawson H, Polansky MM, Anderson RA.

    Horm Metab Res. 2009 Jul;41(7):516-22.PMID: 19593846 [PubMed - indexed for MEDLINE]Related articles

    8.

    Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.

    Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1287-98. Epub 2009 Apr 2.PMID: 19342510 [PubMed - indexed for MEDLINE]Related articles

    9.

    Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.

    Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K.

    Metabolism. 2002 Apr;51(4):409-18.PMID: 11912545 [PubMed - indexed for MEDLINE]Related articles

    10.

    Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.

    Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K.

    J Biol Chem. 2000 Mar 24;275(12):8416-25. Erratum in: J Biol Chem 2001 Jun 8;276(23):20804. PMID: 10722675 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.

    Basciano H, Miller A, Baker C, Naples M, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G323-32. Epub 2009 Jun 4.PMID: 19497957 [PubMed - indexed for MEDLINE]Related articles

    12.

    Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia.

    Chong T, Naples M, Federico L, Taylor D, Smith GJ, Cheung RC, Adeli K.

    Atherosclerosis. 2006 Mar;185(1):21-31. Epub 2005 Jul 5.PMID: 16002078 [PubMed - indexed for MEDLINE]Related articles

    13.

    Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals.

    Qin B, Polansky MM, Sato Y, Adeli K, Anderson RA.

    J Nutr Biochem. 2009 Nov;20(11):901-8. Epub 2008 Nov 6.PMID: 18993048 [PubMed - in process]Related articles

    14.

    Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling.

    Qin B, Anderson RA, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1120-9. Epub 2008 Mar 27.PMID: 18372392 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization.

    Naples M, Federico LM, Xu E, Nelken J, Adeli K.

    Atherosclerosis. 2008 May;198(1):94-103. Epub 2008 Feb 21.PMID: 18093597 [PubMed - indexed for MEDLINE]Related articles

    16.

    Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion.

    Avramoglu RK, Qiu W, Adeli K.

    Front Biosci. 2003 Jan 1;8:d464-76. Review.PMID: 12456312 [PubMed - indexed for MEDLINE]Related articles

    17.

    Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.

    Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K.

    Hepatology. 2008 Dec;48(6):1799-809.PMID: 19026012 [PubMed - indexed for MEDLINE]Related articles

    18.

    Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.

    Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF.

    J Biol Chem. 2002 Aug 9;277(32):28795-802. Epub 2002 Jun 4.PMID: 12048212 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.

    Leung N, Naples M, Uffelman K, Szeto L, Adeli K, Lewis GF.

    Atherosclerosis. 2004 Jun;174(2):235-41.PMID: 15136053 [PubMed - indexed for MEDLINE]Related articles

    20.

    Links between enhanced fatty acid flux, protein kinase C and NFkappaB activation, and apoB-lipoprotein production in the fructose-fed hamster model of insulin resistance.

    Ragheb R, Medhat AM, Shanab GM, Seoudi DM, Fantus IG.

    Biochem Biophys Res Commun. 2008 May 23;370(1):134-9. Epub 2008 Mar 19.PMID: 18358236 [PubMed - indexed for MEDLINE]Related articles

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