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    Results: 1 to 20 of 177

    1.

    Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species.

    Riboulet-Chavey A, Pierron A, Durand I, Murdaca J, Giudicelli J, Van Obberghen E.

    Diabetes. 2006 May;55(5):1289-99.PMID: 16644685 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.

    Cai W, He JC, Zhu L, Chen X, Striker GE, Vlassara H.

    Am J Physiol Cell Physiol. 2008 Jan;294(1):C145-52. Epub 2007 Nov 21.PMID: 18032526 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Preincubation with sodium ascorbate potentiates insulin-dependent PKB/Akt and c-Jun phosphorylation in L6 rat myoblasts challenged with reactive oxygen/nitrogen species.

    Orzechowski A, Lokociejewska M, Pawlikowska P, Kruszewski M.

    Life Sci. 2005 Jun 17;77(5):496-511. Epub 2005 Mar 2.PMID: 15904668 [PubMed - indexed for MEDLINE]Related articles

    4.

    C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

    D'Alessandris C, Lauro R, Presta I, Sesti G.

    Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

    5.

    Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

    Portero-Otín M, Pamplona R, Bellmunt MJ, Ruiz MC, Prat J, Salvayre R, Nègre-Salvayre A.

    Diabetes. 2002 May;51(5):1535-42.PMID: 11978653 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs.

    Cassese A, Esposito I, Fiory F, Barbagallo AP, Paturzo F, Mirra P, Ulianich L, Giacco F, Iadicicco C, Lombardi A, Oriente F, Van Obberghen E, Beguinot F, Formisano P, Miele C.

    J Biol Chem. 2008 Dec 26;283(52):36088-99. Epub 2008 Oct 27.PMID: 18955497 [PubMed - indexed for MEDLINE]Related articles

    7.

    Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway.

    Li G, Barrett EJ, Barrett MO, Cao W, Liu Z.

    Endocrinology. 2007 Jul;148(7):3356-63. Epub 2007 Apr 19.PMID: 17446186 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Modulation of insulin action by advanced glycation endproducts: a new player in the field.

    Schalkwijk CG, Brouwers O, Stehouwer CD.

    Horm Metab Res. 2008 Sep;40(9):614-9. Epub 2008 Sep 15. Review.PMID: 18792872 [PubMed - indexed for MEDLINE]Related articles

    9.

    Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells.

    Wu L, Juurlink BH.

    Hypertension. 2002 Mar 1;39(3):809-14.PMID: 11897769 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes.

    Demozay D, Mas JC, Rocchi S, Van Obberghen E.

    Diabetes. 2008 May;57(5):1216-26. Epub 2008 Jan 3.PMID: 18174527 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.

    de Arriba SG, Stuchbury G, Yarin J, Burnell J, Loske C, Münch G.

    Neurobiol Aging. 2007 Jul;28(7):1044-50. Epub 2006 Jun 15.PMID: 16781798 [PubMed - indexed for MEDLINE]Related articles

    12.

    Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

    Wei Y, Sowers JR, Nistala R, Gong H, Uptergrove GM, Clark SE, Morris EM, Szary N, Manrique C, Stump CS.

    J Biol Chem. 2006 Nov 17;281(46):35137-46. Epub 2006 Sep 17.PMID: 16982630 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Methylglyoxal, oxidative stress, and hypertension.

    Chang T, Wu L.

    Can J Physiol Pharmacol. 2006 Dec;84(12):1229-38. Review.PMID: 17487230 [PubMed - indexed for MEDLINE]Related articles

    14.

    Substrate-induced up-regulation of aldose reductase by methylglyoxal, a reactive oxoaldehyde elevated in diabetes.

    Chang KC, Paek KS, Kim HJ, Lee YS, Yabe-Nishimura C, Seo HG.

    Mol Pharmacol. 2002 May;61(5):1184-91.PMID: 11961137 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.

    Li M, Chiu JF, Gagne J, Fukagawa NK.

    J Cell Physiol. 2008 Nov;217(2):377-87.PMID: 18615585 [PubMed - indexed for MEDLINE]Related articles

    16.

    Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance.

    Banerjee S, Saito K, Ait-Goughoulte M, Meyer K, Ray RB, Ray R.

    J Virol. 2008 Mar;82(6):2606-12. Epub 2007 Dec 26.PMID: 18160431 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Inhibitory effect of vanillic acid on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells.

    Huang SM, Hsu CL, Chuang HC, Shih PH, Wu CH, Yen GC.

    Neurotoxicology. 2008 Nov;29(6):1016-22. Epub 2008 Jul 25.PMID: 18706441 [PubMed - indexed for MEDLINE]Related articles

    18.

    MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

    Bouzakri K, Zierath JR.

    J Biol Chem. 2007 Mar 16;282(11):7783-9. Epub 2007 Jan 16.PMID: 17227768 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats.

    Jia X, Wu L.

    Mol Cell Biochem. 2007 Dec;306(1-2):133-9. Epub 2007 Jul 28.PMID: 17660951 [PubMed - indexed for MEDLINE]Related articles

    20.

    Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats.

    Muñoz MC, Argentino DP, Dominici FP, Turyn D, Toblli JE.

    J Hypertens. 2006 Aug;24(8):1607-17.PMID: 16877964 [PubMed - indexed for MEDLINE]Related articles

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