PubMed

Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.

Buteau J, Spatz ML, Accili D.

Diabetes. 2006 May;55(5):1190-6.PMID: 16644672 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor.

Buteau J, Foisy S, Joly E, Prentki M.

Diabetes. 2003 Jan;52(1):124-32.PMID: 12502502 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.

Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M.

Diabetes. 2001 Oct;50(10):2237-43.PMID: 11574404 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells.

Buteau J, Roduit R, Susini S, Prentki M.

Diabetologia. 1999 Jul;42(7):856-64.PMID: 10440129 [PubMed - indexed for MEDLINE]Related articles

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.PMID: 18162507 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.

Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.

J Biol Chem. 2005 Jun 10;280(23):22297-307. Epub 2005 Apr 6.PMID: 15817464 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.

Buteau J, El-Assaad W, Rhodes CJ, Rosenberg L, Joly E, Prentki M.

Diabetologia. 2004 May;47(5):806-15. Epub 2004 Apr 17.PMID: 15095038 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5'-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway.

Hui H, Nourparvar A, Zhao X, Perfetti R.

Endocrinology. 2003 Apr;144(4):1444-55.PMID: 12639928 [PubMed - indexed for MEDLINE]Related articlesFree article

Cultured pancreatic ductal cells undergo cell cycle re-distribution and beta-cell-like differentiation in response to glucagon-like peptide-1.

Bulotta A, Hui H, Anastasi E, Bertolotto C, Boros LG, Di Mario U, Perfetti R.

J Mol Endocrinol. 2002 Dec;29(3):347-60.PMID: 12459036 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of GLP-1 (glucagon-like peptide 1:7-36 amide) on porcine pancreatic endocrine cell proliferation and insulin secretion.

Nagai K, Tsuchiya K, Ezaki T, Tsuchiya M, Ohgawara H.

Pancreas. 2004 Mar;28(2):138-45.PMID: 15028945 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

Perfetti R, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.

Farilla L, Bulotta A, Hirshberg B, Li Calzi S, Khoury N, Noushmehr H, Bertolotto C, Di Mario U, Harlan DM, Perfetti R.

Endocrinology. 2003 Dec;144(12):5149-58. Epub 2003 Aug 28.PMID: 12960095 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells.

Wang Q, Li L, Xu E, Wong V, Rhodes C, Brubaker PL.

Diabetologia. 2004 Mar;47(3):478-87. Epub 2004 Feb 5.PMID: 14762654 [PubMed - indexed for MEDLINE]Related articles

Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells.

Susini S, Roche E, Prentki M, Schlegel W.

FASEB J. 1998 Sep;12(12):1173-82.PMID: 9737720 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.

Wang X, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2001 May;142(5):1820-7.PMID: 11316746 [PubMed - indexed for MEDLINE]Related articlesFree article

NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

Lawrence MC, Bhatt HS, Easom RA.

Diabetes. 2002 Mar;51(3):691-8.PMID: 11872668 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes outfoxed by GLP-1?

Holz GG, Chepurny OG.

Sci STKE. 2005 Jan 25;2005(268):pe2. Review.PMID: 15671479 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells.

Hui H, Wright C, Perfetti R.

Diabetes. 2001 Apr;50(4):785-96.PMID: 11289043 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic beta-cells.

Hussain MA, Habener JF.

Biochem Biophys Res Commun. 2000 Aug 11;274(3):616-9.PMID: 10924326 [PubMed - indexed for MEDLINE]Related articles