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    Results: 1 to 20 of 1218

    1.

    Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.

    Sloan EK, Pouliot N, Stanley KL, Chia J, Moseley JM, Hards DK, Anderson RL.

    Breast Cancer Res. 2006;8(2):R20. Epub 2006 Apr 11.

    PMID:
    16608535
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

    Zhao Y, Bachelier R, Treilleux I, Pujuguet P, Peyruchaud O, Baron R, Clément-Lacroix P, Clézardin P.

    Cancer Res. 2007 Jun 15;67(12):5821-30.

    PMID:
    17575150
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis.

    Harms JF, Welch DR, Samant RS, Shevde LA, Miele ME, Babu GR, Goldberg SF, Gilman VR, Sosnowski DM, Campo DA, Gay CV, Budgeon LR, Mercer R, Jewell J, Mastro AM, Donahue HJ, Erin N, Debies MT, Meehan WJ, Jones AL, Mbalaviele G, Nickols A, Christensen ND, Melly R, Beck LN, Kent J, Rader RK, Kotyk JJ, Pagel MD, Westlin WF, Griggs DW.

    Clin Exp Metastasis. 2004;21(2):119-28.

    PMID:
    15168729
    [PubMed - indexed for MEDLINE]
    4.

    Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

    Eckhardt BL, Parker BS, van Laar RK, Restall CM, Natoli AL, Tavaria MD, Stanley KL, Sloan EK, Moseley JM, Anderson RL.

    Mol Cancer Res. 2005 Jan;3(1):1-13.

    PMID:
    15671244
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Correlation between extent of osteolytic damage and metastatic burden of human breast cancer metastasis in nude mice: real-time PCR quantitation.

    Tester AM, Sharp JA, Dhanesuan N, Waltham M, Thompson EW.

    Clin Exp Metastasis. 2002;19(5):377-83.

    PMID:
    12198765
    [PubMed - indexed for MEDLINE]
    6.

    Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis.

    Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA.

    J Cell Biol. 2000 Feb 21;148(4):779-90. Erratum in: J Cell Biol 2000 Apr 3;149(1):following 236.

    PMID:
    10684258
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice.

    Jenkins DE, Hornig YS, Oei Y, Dusich J, Purchio T.

    Breast Cancer Res. 2005;7(4):R444-54. Epub 2005 Apr 8.

    PMID:
    15987449
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases.

    Kelly T, Suva LJ, Huang Y, Macleod V, Miao HQ, Walker RC, Sanderson RD.

    Cancer Res. 2005 Jul 1;65(13):5778-84.

    PMID:
    15994953
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Inhibition of skeletal metastasis by ectopic ERalpha expression in ERalpha-negative human breast cancer cell lines.

    Bandyopadhyay A, Wang L, Chin SH, Sun LZ.

    Neoplasia. 2007 Feb;9(2):113-8.

    PMID:
    17356707
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD mammary epithelial cells.

    Pinkas J, Martin SS, Leder P.

    Mol Cancer Res. 2004 Oct;2(10):551-6.

    PMID:
    15498929
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling.

    McCabe NP, De S, Vasanji A, Brainard J, Byzova TV.

    Oncogene. 2007 Sep 13;26(42):6238-43. Epub 2007 Mar 19.

    PMID:
    17369840
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Identification of prospective factors promoting osteotropism in breast cancer: a potential role for CITED2.

    Lau WM, Weber KL, Doucet M, Chou YT, Brady K, Kowalski J, Tsai HL, Yang J, Kominsky SL.

    Int J Cancer. 2010 Feb 15;126(4):876-84.

    PMID:
    19642106
    [PubMed - indexed for MEDLINE]
    13.

    Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells.

    Rolli M, Fransvea E, Pilch J, Saven A, Felding-Habermann B.

    Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9482-7. Epub 2003 Jul 21.

    PMID:
    12874388
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.

    Price JT, Quinn JM, Sims NA, Vieusseux J, Waldeck K, Docherty SE, Myers D, Nakamura A, Waltham MC, Gillespie MT, Thompson EW.

    Cancer Res. 2005 Jun 1;65(11):4929-38.

    PMID:
    15930315
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.

    Borrirukwanit K, Lafleur MA, Mercuri FA, Blick T, Price JT, Fridman R, Pereira JJ, Leardkamonkarn V, Thompson EW.

    Matrix Biol. 2007 May;26(4):291-305. Epub 2006 Nov 7.

    PMID:
    17175151
    [PubMed - indexed for MEDLINE]
    16.

    Inhibition of alpha(v)beta3 integrin reduces angiogenesis, bone turnover, and tumor cell proliferation in experimental prostate cancer bone metastases.

    Nemeth JA, Cher ML, Zhou Z, Mullins C, Bhagat S, Trikha M.

    Clin Exp Metastasis. 2003;20(5):413-20.

    PMID:
    14524530
    [PubMed - indexed for MEDLINE]
    17.

    Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

    Boucharaba A, Serre CM, Grès S, Saulnier-Blache JS, Bordet JC, Guglielmi J, Clézardin P, Peyruchaud O.

    J Clin Invest. 2004 Dec;114(12):1714-25.

    PMID:
    15599396
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    The effect of versican G3 domain on local breast cancer invasiveness and bony metastasis.

    Yee AJ, Akens M, Yang BL, Finkelstein J, Zheng PS, Deng Z, Yang B.

    Breast Cancer Res. 2007;9(4):R47.

    PMID:
    17662123
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice.

    Sasaki A, Boyce BF, Story B, Wright KR, Chapman M, Boyce R, Mundy GR, Yoneda T.

    Cancer Res. 1995 Aug 15;55(16):3551-7.

    PMID:
    7627963
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis.

    Guise TA, Yin JJ, Taylor SD, Kumagai Y, Dallas M, Boyce BF, Yoneda T, Mundy GR.

    J Clin Invest. 1996 Oct 1;98(7):1544-9.

    PMID:
    8833902
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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