PubMed

The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta.

Miller MJ, Ahmed S, Bobrowski P, Haqqi TM.

BMC Complement Altern Med. 2006 Apr 7;6:13.PMID: 16603065 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

Martin G, Andriamanalijaona R, Grässel S, Dreier R, Mathy-Hartert M, Bogdanowicz P, Boumédiene K, Henrotin Y, Bruckner P, Pujol JP.

Arthritis Rheum. 2004 Nov;50(11):3549-60.PMID: 15529381 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes.

Im HJ, Pacione C, Chubinskaya S, Van Wijnen AJ, Sun Y, Loeser RF.

J Biol Chem. 2003 Jul 11;278(28):25386-94. Epub 2003 May 6.PMID: 12734180 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor 1-induced interleukin-1 receptor II overrides the activity of interleukin-1 and controls the homeostasis of the extracellular matrix of cartilage.

Wang J, Elewaut D, Veys EM, Verbruggen G.

Arthritis Rheum. 2003 May;48(5):1281-91.PMID: 12746901 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1.

Loeser RF, Carlson CS, Del Carlo M, Cole A.

Arthritis Rheum. 2002 Sep;46(9):2349-57.PMID: 12355482 [PubMed - indexed for MEDLINE]Related articlesFree article

Haem oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes.

Guillén M, Megías J, Gomar F, Alcaraz M.

J Pathol. 2008 Mar;214(4):515-22.PMID: 18200630 [PubMed - indexed for MEDLINE]Related articles

Anabolic actions of IGF-I and TGF-beta1 on Interleukin-1beta-treated human articular chondrocytes: evaluation in two and three dimensional cultures.

Seifarth C, Csaki C, Shakibaei M.

Histol Histopathol. 2009 Oct;24(10):1245-62.PMID: 19688693 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7.

Bobacz K, Sunk IG, Hofstaetter JG, Amoyo L, Toma CD, Akira S, Weichhart T, Saemann M, Smolen JS.

Arthritis Rheum. 2007 Jun;56(6):1880-93.PMID: 17530716 [PubMed - indexed for MEDLINE]Related articlesFree article

Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro.

Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM.

J Nutr. 2005 Sep;135(9):2096-102.PMID: 16140882 [PubMed - indexed for MEDLINE]Related articlesFree article

Avocado/soybean unsaponifiables increase aggrecan synthesis and reduce catabolic and proinflammatory mediator production by human osteoarthritic chondrocytes.

Henrotin YE, Sanchez C, Deberg MA, Piccardi N, Guillou GB, Msika P, Reginster JY.

J Rheumatol. 2003 Aug;30(8):1825-34.PMID: 12913942 [PubMed - indexed for MEDLINE]Related articles

Chondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1beta-stimulated chondrocytes--study in hypoxic alginate bead cultures.

Legendre F, Baugé C, Roche R, Saurel AS, Pujol JP.

Osteoarthritis Cartilage. 2008 Jan;16(1):105-14. Epub 2007 Jul 12.PMID: 17625924 [PubMed - indexed for MEDLINE]Related articles

ADAMTS-1, a gene product of articular chondrocytes in vivo and in vitro, is downregulated by interleukin 1beta.

Wachsmuth L, Bau B, Fan Z, Pecht A, Gerwin N, Aigner T.

J Rheumatol. 2004 Feb;31(2):315-20.PMID: 14760803 [PubMed - indexed for MEDLINE]Related articles

Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor.

Kolettas E, Muir HI, Barrett JC, Hardingham TE.

Rheumatology (Oxford). 2001 Oct;40(10):1146-56.PMID: 11600745 [PubMed - indexed for MEDLINE]Related articlesFree article

Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes.

Chabane N, Zayed N, Afif H, Mfuna-Endam L, Benderdour M, Boileau C, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

Osteoarthritis Cartilage. 2008 Oct;16(10):1267-74. Epub 2008 Apr 15.PMID: 18417374 [PubMed - indexed for MEDLINE]Related articles

Aceclofenac increases the synthesis of interleukin 1 receptor antagonist and decreases the production of nitric oxide in human articular chondrocytes.

Maneiro E, López-Armada MJ, Fernández-Sueiro JL, Lema B, Galdo F, Blanco FJ.

J Rheumatol. 2001 Dec;28(12):2692-9.PMID: 11764219 [PubMed - indexed for MEDLINE]Related articles

Transcriptional and proteolytic regulation of the insulin-like growth factor-I system of equine articular chondrocytes by recombinant equine interleukin-1beta.

Porter RM, Akers RM, Howard RD, Forsten-Williams K.

J Cell Physiol. 2006 Nov;209(2):542-50.PMID: 16897751 [PubMed - indexed for MEDLINE]Related articles

Influence of simvastatin on the production of pro-inflammatory cytokines and nitric oxide by activated human chondrocytes.

Dombrecht EJ, Van Offel JF, Bridts CH, Ebo DG, Seynhaeve V, Schuerwegh AJ, Stevens WJ, De Clerck LS.

Clin Exp Rheumatol. 2007 Jul-Aug;25(4):534-9.PMID: 17888208 [PubMed - indexed for MEDLINE]Related articles

Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis.

Studer RK, Georgescu HI, Miller LA, Evans CH.

Arthritis Rheum. 1999 Feb;42(2):248-57.PMID: 10025918 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary human articular chondrocytes, dedifferentiated chondrocytes, and synoviocytes exhibit differential responsiveness to interleukin-4: correlation with the expression pattern of the common receptor gamma chain.

Guicheux J, Palmer G, Relic B, Mezin F, Caverzasio J, Apostolides P, Gauchat JF, Gabay C, Guerne PA.

J Cell Physiol. 2002 Jul;192(1):93-101.PMID: 12115740 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor 1 and corticosteroid modulation of chondrocyte metabolic and mitogenic activities in interleukin 1-conditioned equine cartilage.

Frisbie DD, Nixon AJ.

Am J Vet Res. 1997 May;58(5):524-30. Erratum in: Am J Vet Res 1997 Jul;58(7):701. PMID: 9140562 [PubMed - indexed for MEDLINE]Related articles