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    Results: 1 to 20 of 239

    1.

    A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.

    Zhao Z, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM.

    BMC Neurosci. 2006 Apr 3;7:29.PMID: 16584562 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.

    Liu R, Li B, Flanagan SW, Oberley LW, Gozal D, Qiu M.

    J Neurochem. 2002 Feb;80(3):488-500.PMID: 11905995 [PubMed - indexed for MEDLINE]Related articles

    3.

    Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.

    Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L, Figlewicz DA, Shaw PJ.

    Brain. 2002 Jul;125(Pt 7):1522-33.PMID: 12077002 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis.

    Kiaei M, Kipiani K, Petri S, Chen J, Calingasan NY, Beal MF.

    Neurodegener Dis. 2005;2(5):246-54.PMID: 16909005 [PubMed - indexed for MEDLINE]Related articles

    5.

    Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.

    Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R.

    J Neurosci. 2008 Apr 16;28(16):4115-22.PMID: 18417691 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS.

    Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ.

    J Neurosci. 2007 Aug 22;27(34):9201-19.PMID: 17715356 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.

    Martin LJ.

    Rev Neurosci. 2007;18(2):115-36. Review.PMID: 17593875 [PubMed - indexed for MEDLINE]Related articles

    8.

    Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.

    Gould TW, Buss RR, Vinsant S, Prevette D, Sun W, Knudson CM, Milligan CE, Oppenheim RW.

    J Neurosci. 2006 Aug 23;26(34):8774-86.PMID: 16928866 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Over-expression of Hsp27 does not influence disease in the mutant SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

    Krishnan J, Vannuvel K, Andries M, Waelkens E, Robberecht W, Van Den Bosch L.

    J Neurochem. 2008 Sep;106(5):2170-83. Epub 2008 Jul 4.PMID: 18624915 [PubMed - indexed for MEDLINE]Related articles

    10.

    In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.

    Niessen HG, Angenstein F, Sander K, Kunz WS, Teuchert M, Ludolph AC, Heinze HJ, Scheich H, Vielhaber S.

    Exp Neurol. 2006 Oct;201(2):293-300. Epub 2006 Jun 5.PMID: 16740261 [PubMed - indexed for MEDLINE]Related articles

    11.

    Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.

    Li QX, Mok SS, Laughton KM, McLean CA, Volitakis I, Cherny RA, Cheung NS, White AR, Masters CL.

    Aging Cell. 2006 Apr;5(2):153-65.PMID: 16626394 [PubMed - indexed for MEDLINE]Related articles

    12.

    The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS.

    Messi ML, Clark HM, Prevette DM, Oppenheim RW, Delbono O.

    Exp Neurol. 2007 Sep;207(1):52-63. Epub 2007 Jun 2.PMID: 17597610 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Neurodegeneration induced by complex I inhibition in a cellular model of familial amyotrophic lateral sclerosis.

    Rizzardini M, Lupi M, Mangolini A, Babetto E, Ubezio P, Cantoni L.

    Brain Res Bull. 2006 Apr 28;69(4):465-74. Epub 2006 Mar 10.PMID: 16624679 [PubMed - indexed for MEDLINE]Related articles

    14.

    Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.

    Li W, Brakefield D, Pan Y, Hunter D, Myckatyn TM, Parsadanian A.

    Exp Neurol. 2007 Feb;203(2):457-71. Epub 2006 Oct 10.PMID: 17034790 [PubMed - indexed for MEDLINE]Related articles

    15.

    Light therapy and supplementary Riboflavin in the SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis (FALS).

    Moges H, Vasconcelos OM, Campbell WW, Borke RC, McCoy JA, Kaczmarczyk L, Feng J, Anders JJ.

    Lasers Surg Med. 2009 Jan;41(1):52-9.PMID: 19143012 [PubMed - indexed for MEDLINE]Related articles

    16.

    Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.

    Sharp PS, Akbar MT, Bouri S, Senda A, Joshi K, Chen HJ, Latchman DS, Wells DJ, de Belleroche J.

    Neurobiol Dis. 2008 Apr;30(1):42-55. Epub 2007 Dec 23.PMID: 18255302 [PubMed - indexed for MEDLINE]Related articles

    17.

    Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse.

    Hamadeh MJ, Rodriguez MC, Kaczor JJ, Tarnopolsky MA.

    Muscle Nerve. 2005 Feb;31(2):214-20.PMID: 15625688 [PubMed - indexed for MEDLINE]Related articles

    18.

    Recombinant human erythropoietin suppresses symptom onset and progression of G93A-SOD1 mouse model of ALS by preventing motor neuron death and inflammation.

    Koh SH, Kim Y, Kim HY, Cho GW, Kim KS, Kim SH.

    Eur J Neurosci. 2007 Apr;25(7):1923-30.PMID: 17439481 [PubMed - indexed for MEDLINE]Related articles

    19.

    Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.

    Bordet T, Buisson B, Michaud M, Drouot C, Galéa P, Delaage P, Akentieva NP, Evers AS, Covey DF, Ostuni MA, Lacapère JJ, Massaad C, Schumacher M, Steidl EM, Maux D, Delaage M, Henderson CE, Pruss RM.

    J Pharmacol Exp Ther. 2007 Aug;322(2):709-20. Epub 2007 May 11.PMID: 17496168 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

    Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP.

    J Neurosci. 2008 Oct 8;28(41):10234-44.PMID: 18842883 [PubMed - indexed for MEDLINE]Related articlesFree article

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