PubMed

Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin.

Ellger B, Debaveye Y, Vanhorebeek I, Langouche L, Giulietti A, Van Etten E, Herijgers P, Mathieu C, Van den Berghe G.

Diabetes. 2006 Apr;55(4):1096-105.PMID: 16567534 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity.

Ellger B, Richir MC, van Leeuwen PA, Debaveye Y, Langouche L, Vanhorebeek I, Teerlink T, Van den Berghe G.

Endocrinology. 2008 Jun;149(6):3148-57. Epub 2008 Feb 21.PMID: 18292189 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of regional nitric oxide metabolism: blood glucose control or insulin?

Ellger B, Langouche L, Richir M, Debaveye Y, Vanhorebeek I, Teerlink T, Van Leeuwen PA, Van den Berghe G.

Intensive Care Med. 2008 Aug;34(8):1525-33. Epub 2008 Apr 22. Erratum in: Intensive Care Med. 2008 Sep;34(9):1740. Teerlink, Tom [added]. PMID: 18427775 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness.

Vanhorebeek I, Ellger B, De Vos R, Boussemaere M, Debaveye Y, Perre SV, Rabbani N, Thornalley PJ, Van den Berghe G.

Crit Care Med. 2009 Apr;37(4):1355-64.PMID: 19242345 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemic kidney damage in an animal model of prolonged critical illness.

Vanhorebeek I, Gunst J, Ellger B, Boussemaere M, Lerut E, Debaveye Y, Rabbani N, Thornalley PJ, Schetz M, Van den Berghe G.

Kidney Int. 2009 Sep;76(5):512-20. Epub 2009 Jun 17.PMID: 19536085 [PubMed - indexed for MEDLINE]Related articles

Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness.

Weekers F, Giulietti AP, Michalaki M, Coopmans W, Van Herck E, Mathieu C, Van den Berghe G.

Endocrinology. 2003 Dec;144(12):5329-38. Epub 2003 Aug 28.PMID: 12960028 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of insulin therapy in critically ill patients.

Langouche L, Vanhorebeek I, Van den Berghe G.

Treat Endocrinol. 2005;4(6):353-60. Review.PMID: 16318401 [PubMed - indexed for MEDLINE]Related articles

Intensive insulin therapy in the intensive care unit: update on clinical impact and mechanisms of action.

Vanhorebeek I, Langouche L, Van den Berghe G.

Endocr Pract. 2006 Jul-Aug;12 Suppl 3:14-22. Review.PMID: 16905512 [PubMed - indexed for MEDLINE]Related articles

Increasing intravenous glucose load in the presence of normoglycemia: Effect on outcome and metabolism in critically ill rabbits.

Derde S, Vanhorebeek I, Ververs EJ, Vanhees I, Darras VM, Van Herck E, Larsson L, Van den Berghe G.

Crit Care Med. 2009 Oct 20. [Epub ahead of print]PMID: 19851097 [PubMed - as supplied by publisher]Related articles

Glucose metabolism and insulin resistance in sepsis.

Van Cromphaut SJ, Vanhorebeek I, Van den Berghe G.

Curr Pharm Des. 2008;14(19):1887-99. Review.PMID: 18691100 [PubMed - indexed for MEDLINE]Related articles

Indication and practical use of intensive insulin therapy in the critically ill.

Mebis L, Gunst J, Langouche L, Vanhorebeek I, Van den Berghe G.

Curr Opin Crit Care. 2007 Aug;13(4):392-8. Review.PMID: 17599008 [PubMed - indexed for MEDLINE]Related articles

Tight blood glucose control: what is the evidence?

Vanhorebeek I, Langouche L, Van den Berghe G.

Crit Care Med. 2007 Sep;35(9 Suppl):S496-502. Review.PMID: 17713399 [PubMed - indexed for MEDLINE]Related articles

The importance of strict blood glucose control with insulin therapy in the intensive care unit.

van den Heuvel I, Vanhorebeek I, Van den Berghe G.

Curr Diabetes Rev. 2008 Aug;4(3):227-33. Review.PMID: 18690905 [PubMed - indexed for MEDLINE]Related articles

Impact of tight glycemic control in severely burned children.

Pham TN, Warren AJ, Phan HH, Molitor F, Greenhalgh DG, Palmieri TL.

J Trauma. 2005 Nov;59(5):1148-54.PMID: 16385293 [PubMed - indexed for MEDLINE]Related articles

Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness.

Weekers F, Michalaki M, Coopmans W, Van Herck E, Veldhuis JD, Darras VM, Van den Berghe G.

Endocrinology. 2004 Jan;145(1):205-13. Epub 2003 Oct 9.PMID: 14551231 [PubMed - indexed for MEDLINE]Related articlesFree article

Tight blood glucose control with insulin in the ICU: facts and controversies.

Vanhorebeek I, Langouche L, Van den Berghe G.

Chest. 2007 Jul;132(1):268-78. Review.PMID: 17625087 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose metabolism and insulin therapy.

Langouche L, Van den Berghe G.

Crit Care Clin. 2006 Jan;22(1):119-29, vii. Review.PMID: 16399023 [PubMed - indexed for MEDLINE]Related articles

Effect of intensive insulin therapy on insulin sensitivity in the critically ill.

Langouche L, Vander Perre S, Wouters PJ, D'Hoore A, Hansen TK, Van den Berghe G.

J Clin Endocrinol Metab. 2007 Oct;92(10):3890-7. Epub 2007 Jul 31.PMID: 17666481 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapy insight: the effect of tight glycemic control in acute illness.

Langouche L, Vanhorebeek I, Van den Berghe G.

Nat Clin Pract Endocrinol Metab. 2007 Mar;3(3):270-8. Review.PMID: 17315035 [PubMed - indexed for MEDLINE]Related articles

Cortisol response to critical illness: effect of intensive insulin therapy.

Vanhorebeek I, Peeters RP, Vander Perre S, Jans I, Wouters PJ, Skogstrand K, Hansen TK, Bouillon R, Van den Berghe G.

J Clin Endocrinol Metab. 2006 Oct;91(10):3803-13. Epub 2006 Jul 25.PMID: 16868064 [PubMed - indexed for MEDLINE]Related articlesFree article