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    Results: 1 to 20 of 491

    1.

    Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.

    Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS.

    Diabetes. 2006 Apr;55(4):1080-7.PMID: 16567532 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia.

    Chan O, Lawson M, Zhu W, Beverly JL, Sherwin RS.

    Diabetes. 2007 Apr;56(4):1120-6. Epub 2007 Jan 24.PMID: 17251273 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia.

    Chan O, Cheng H, Herzog R, Czyzyk D, Zhu W, Wang A, McCrimmon RJ, Seashore MR, Sherwin RS.

    Diabetes. 2008 May;57(5):1363-70. Epub 2008 Mar 28.PMID: 18375441 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia, and insulin treatment normalizes HPA but not epinephrine responses.

    Chan O, Chan S, Inouye K, Shum K, Matthews SG, Vranic M.

    Diabetes. 2002 Jun;51(6):1681-9.PMID: 12031953 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

    McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Aug;53(8):1953-8.PMID: 15277372 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats.

    Borg MA, Borg WP, Tamborlane WV, Brines ML, Shulman GI, Sherwin RS.

    Diabetes. 1999 Mar;48(3):584-7.PMID: 10078560 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.

    Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ.

    Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1702-8. Epub 2009 Apr 8.PMID: 19357294 [PubMed - indexed for MEDLINE]Related articles

    8.

    Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses.

    Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Oct;53(10):2542-51.PMID: 15448082 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Role of corticotrophin-releasing hormone in the impairment of counterregulatory responses to hypoglycemia.

    Flanagan DE, Keshavarz T, Evans ML, Flanagan S, Fan X, Jacob RJ, Sherwin RS.

    Diabetes. 2003 Mar;52(3):605-13.PMID: 12606499 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

    Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI.

    J Clin Invest. 1997 Jan 15;99(2):361-5.PMID: 9006005 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Type 1 corticotropin-releasing factor receptors in the ventromedial hypothalamus promote hypoglycemia-induced hormonal counterregulation.

    Cheng H, Zhou L, Zhu W, Wang A, Tang C, Chan O, Sherwin RS, McCrimmon RJ.

    Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E705-12. Epub 2007 Jun 19.PMID: 17578887 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Antecedent short-term central nervous system administration of estrogen and progesterone alters counterregulatory responses to hypoglycemia in conscious male rats.

    Sandoval DA, Gong B, Davis SN.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1511-6. Epub 2007 Oct 16.PMID: 17940215 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

    Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI.

    J Clin Invest. 1994 Apr;93(4):1677-82.PMID: 8163668 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The effects of dehydroepiandrosterone sulfate on counterregulatory responses during repeated hypoglycemia in conscious normal rats.

    Sandoval DA, Ping L, Neill RA, Morrey S, Davis SN.

    Diabetes. 2004 Mar;53(3):679-86.PMID: 14988252 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia.

    McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS.

    Diabetes. 2008 Feb;57(2):444-50. Epub 2007 Oct 31.PMID: 17977955 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.

    McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS.

    Diabetes. 2005 Nov;54(11):3169-74.PMID: 16249441 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation.

    Borg MA, Tamborlane WV, Shulman GI, Sherwin RS.

    Diabetes. 2003 Mar;52(3):663-6.PMID: 12606506 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Evidence for a hypothalamic-pituitary versus adrenal cortical effect of glycemic control on counterregulatory hormone responses to hypoglycemia in insulin-dependent diabetes mellitus.

    Kinsley BT, Simonson DC.

    J Clin Endocrinol Metab. 1996 Feb;81(2):684-91.PMID: 8636289 [PubMed - indexed for MEDLINE]Related articles

    19.

    Counterregulatory deficits occur within 24 h of a single hypoglycemic episode in conscious, unrestrained, chronically cannulated mice.

    Jacobson L, Ansari T, McGuinness OP.

    Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E678-84.PMID: 16533951 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia.

    Chan O, Inouye K, Akirav EM, Park E, Riddell MC, Matthews SG, Vranic M.

    Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R235-46. Epub 2005 Mar 17.PMID: 15774766 [PubMed - indexed for MEDLINE]Related articles

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