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    Results: 1 to 20 of 151

    1.

    Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria.

    Rachek LI, Thornley NP, Grishko VI, LeDoux SP, Wilson GL.

    Diabetes. 2006 Apr;55(4):1022-8.PMID: 16567524 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis.

    Rachek LI, Grishko VI, Ledoux SP, Wilson GL.

    Free Radic Biol Med. 2006 Mar 1;40(5):754-62. Epub 2005 Oct 18.PMID: 16520228 [PubMed - indexed for MEDLINE]Related articles

    3.

    Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8-oxoguanine glycosylase to mitochondria.

    Druzhyna NM, Musiyenko SI, Wilson GL, LeDoux SP.

    J Biol Chem. 2005 Jun 3;280(22):21673-9. Epub 2005 Apr 4.PMID: 15811855 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells.

    Ruchko M, Gorodnya O, LeDoux SP, Alexeyev MF, Al-Mehdi AB, Gillespie MN.

    Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L530-5. Epub 2004 Nov 24.PMID: 15563690 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria.

    Rachek LI, Grishko VI, Musiyenko SI, Kelley MR, LeDoux SP, Wilson GL.

    J Biol Chem. 2002 Nov 22;277(47):44932-7. Epub 2002 Sep 19.PMID: 12244119 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Involvement of mtDNA damage in free fatty acid-induced apoptosis.

    Grishko V, Rachek L, Musiyenko S, Ledoux SP, Wilson GL.

    Free Radic Biol Med. 2005 Mar 15;38(6):755-62.PMID: 15721986 [PubMed - indexed for MEDLINE]Related articles

    7.

    Targeting human 8-oxoguanine DNA glycosylase (hOGG1) to mitochondria enhances cisplatin cytotoxicity in hepatoma cells.

    Zhang H, Mizumachi T, Carcel-Trullols J, Li L, Naito A, Spencer HJ, Spring PM, Smoller BR, Watson AJ, Margison GP, Higuchi M, Fan CY.

    Carcinogenesis. 2007 Aug;28(8):1629-37. Epub 2007 Mar 26.PMID: 17389610 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis.

    Chatterjee A, Chang X, Nagpal JK, Chang S, Upadhyay S, Califano J, Trink B, Sidransky D.

    Oncogene. 2008 Jun 12;27(26):3710-20. Epub 2008 Feb 4.PMID: 18246124 [PubMed - indexed for MEDLINE]Related articles

    9.

    Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress.

    Druzhyna NM, Hollensworth SB, Kelley MR, Wilson GL, Ledoux SP.

    Glia. 2003 Jun;42(4):370-8.PMID: 12730957 [PubMed - indexed for MEDLINE]Related articles

    10.

    Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.

    Chatterjee A, Mambo E, Zhang Y, Deweese T, Sidransky D.

    BMC Cancer. 2006 Oct 3;6:235.PMID: 17018150 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress.

    Rachek LI, Grishko VI, Alexeyev MF, Pastukh VV, LeDoux SP, Wilson GL.

    Nucleic Acids Res. 2004 Jun 15;32(10):3240-7. Print 2004.PMID: 15199172 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria.

    Dobson AW, Xu Y, Kelley MR, LeDoux SP, Wilson GL.

    J Biol Chem. 2000 Dec 1;275(48):37518-23.PMID: 10982789 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.

    Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A.

    Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E540-50. Epub 2008 Jan 15.PMID: 18198352 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in l6 rat skeletal muscle cells.

    Rachek LI, Musiyenko SI, LeDoux SP, Wilson GL.

    Endocrinology. 2007 Jan;148(1):293-9. Epub 2006 Oct 5.PMID: 17023529 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Constructing the eukaryotic expression vector to study preliminarily the functions of hammerhead ribozyme targeting base excision repair gene HOGG1.

    Zhang ZZ, Zhang Q, Wu M.

    Sichuan Da Xue Xue Bao Yi Xue Ban. 2006 Mar;37(2):165-70.PMID: 16608066 [PubMed - indexed for MEDLINE]Related articles

    16.

    The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress.

    Shokolenko IN, Alexeyev MF, Robertson FM, LeDoux SP, Wilson GL.

    DNA Repair (Amst). 2003 May 13;2(5):471-82.PMID: 12713808 [PubMed - indexed for MEDLINE]Related articles

    17.

    Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.

    Schnell S, Schaefer M, Schöfl C.

    Mol Cell Endocrinol. 2007 Jan 15;263(1-2):173-80. Epub 2006 Nov 13.PMID: 17101212 [PubMed - indexed for MEDLINE]Related articles

    18.

    Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts.

    Youn CK, Song PI, Kim MH, Kim JS, Hyun JW, Choi SJ, Yoon SP, Chung MH, Chang IY, You HJ.

    Mol Cancer Res. 2007 Oct;5(10):1083-98.PMID: 17951408 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis.

    Ricci C, Pastukh V, Leonard J, Turrens J, Wilson G, Schaffer D, Schaffer SW.

    Am J Physiol Cell Physiol. 2008 Feb;294(2):C413-22. Epub 2007 Dec 12.PMID: 18077603 [PubMed - indexed for MEDLINE]Related articlesFree article

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