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    Results: 1 to 20 of 289

    1.

    Opposite effect of JAK2 on insulin-dependent activation of mitogen-activated protein kinases and Akt in muscle cells: possible target to ameliorate insulin resistance.

    Thirone AC, JeBailey L, Bilan PJ, Klip A.

    Diabetes. 2006 Apr;55(4):942-51.PMID: 16567515 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase.

    Somwar R, Kim DY, Sweeney G, Huang C, Niu W, Lador C, Ramlal T, Klip A.

    Biochem J. 2001 Nov 1;359(Pt 3):639-49.PMID: 11672439 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells.

    Sweeney G, Keen J, Somwar R, Konrad D, Garg R, Klip A.

    Endocrinology. 2001 Nov;142(11):4806-12.PMID: 11606447 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.

    Huang C, Thirone AC, Huang X, Klip A.

    J Biol Chem. 2005 May 13;280(19):19426-35. Epub 2005 Mar 11.PMID: 15764603 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

    Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS.

    J Biol Chem. 2008 Oct 10;283(41):27653-67. Epub 2008 Jul 31.PMID: 18669636 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism.

    Miele C, Riboulet A, Maitan MA, Oriente F, Romano C, Formisano P, Giudicelli J, Beguinot F, Van Obberghen E.

    J Biol Chem. 2003 Nov 28;278(48):47376-87. Epub 2003 Sep 11.PMID: 12970360 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Maturation of the regulation of GLUT4 activity by p38 MAPK during L6 cell myogenesis.

    Niu W, Huang C, Nawaz Z, Levy M, Somwar R, Li D, Bilan PJ, Klip A.

    J Biol Chem. 2003 May 16;278(20):17953-62. Epub 2003 Mar 11.PMID: 12637564 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.

    Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A.

    Diabetes. 2008 Aug;57(8):2066-73. Epub 2008 Apr 28.PMID: 18443205 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Janus kinase-signal transducer and activator of transcription mediates phosphatidic acid-induced interleukin (IL)-1beta and IL-6 production.

    Lee C, Lim HK, Sakong J, Lee YS, Kim JR, Baek SH.

    Mol Pharmacol. 2006 Mar;69(3):1041-7. Epub 2005 Dec 14.PMID: 16354768 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

    Carvalheira JB, Calegari VC, Zecchin HG, Nadruz W Jr, Guimarães RB, Ribeiro EB, Franchini KG, Velloso LA, Saad MJ.

    Endocrinology. 2003 Dec;144(12):5604-14. Epub 2003 Sep 4.PMID: 12960006 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

    D'Alessandris C, Lauro R, Presta I, Sesti G.

    Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

    12.

    Acute and chronic leptin treatment mediate contrasting effects on signaling, glucose uptake, and GLUT4 translocation in L6-GLUT4myc myotubes.

    Tajmir P, Kwan JJ, Kessas M, Mozammel S, Sweeney G.

    J Cell Physiol. 2003 Oct;197(1):122-30.PMID: 12942548 [PubMed - indexed for MEDLINE]Related articles

    13.

    ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells.

    Izawa Y, Yoshizumi M, Fujita Y, Ali N, Kanematsu Y, Ishizawa K, Tsuchiya K, Obata T, Ebina Y, Tomita S, Tamaki T.

    Exp Cell Res. 2005 Aug 15;308(2):291-9.PMID: 15921682 [PubMed - indexed for MEDLINE]Related articles

    14.

    Multiple signaling pathways mediate LIF-induced skeletal muscle satellite cell proliferation.

    Spangenburg EE, Booth FW.

    Am J Physiol Cell Physiol. 2002 Jul;283(1):C204-11.PMID: 12055089 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats.

    Ishizawa K, Yoshizumi M, Tsuchiya K, Takishita E, Nakaya Y, Kishi K, Ebina Y, Houchi H, Minakuchi K, Tamaki T.

    Eur J Pharmacol. 2001 Nov 2;430(2-3):359-67.PMID: 11711055 [PubMed - indexed for MEDLINE]Related articles

    16.

    Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation.

    Ogunwobi O, Mutungi G, Beales IL.

    Endocrinology. 2006 Sep;147(9):4505-16. Epub 2006 Jun 1.PMID: 16740977 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.

    Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM.

    Mol Cell Biol. 2004 Oct;24(19):8778-89.PMID: 15367694 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle.

    Nieto-Vazquez I, Fernández-Veledo S, de Alvaro C, Lorenzo M.

    Diabetes. 2008 Dec;57(12):3211-21. Epub 2008 Sep 16.PMID: 18796617 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Enhanced insulin action on glucose transport and insulin signaling in 7-day unweighted rat soleus muscle.

    O'Keefe MP, Perez FR, Sloniger JA, Tischler ME, Henriksen EJ.

    J Appl Physiol. 2004 Jul;97(1):63-71. Epub 2004 Mar 5.PMID: 15004002 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Insulin acts via mitogen-activated protein kinase phosphorylation in rabbit blastocysts.

    Navarrete Santos A, Tonack S, Kirstein M, Pantaleon M, Kaye P, Fischer B.

    Reproduction. 2004 Nov;128(5):517-26.PMID: 15509697 [PubMed - indexed for MEDLINE]Related articlesFree article

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