PubMed

Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha.

Park CW, Kim HW, Ko SH, Chung HW, Lim SW, Yang CW, Chang YS, Sugawara A, Guan Y, Breyer MD.

Diabetes. 2006 Apr;55(4):885-93.PMID: 16567507 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice.

Park CW, Zhang Y, Zhang X, Wu J, Chen L, Cha DR, Su D, Hwang MT, Fan X, Davis L, Striker G, Zheng F, Breyer M, Guan Y.

Kidney Int. 2006 May;69(9):1511-7.PMID: 16672921 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.

Cha DR, Zhang X, Zhang Y, Wu J, Su D, Han JY, Fang X, Yu B, Breyer MD, Guan Y.

Diabetes. 2007 Aug;56(8):2036-45. Epub 2007 May 29.PMID: 17536062 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels.

Murray AJ, Panagia M, Hauton D, Gibbons GF, Clarke K.

Diabetes. 2005 Dec;54(12):3496-502.PMID: 16306367 [PubMed - indexed for MEDLINE]Related articlesFree article

p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency.

Wolf G, Schanze A, Stahl RA, Shankland SJ, Amann K.

Kidney Int. 2005 Oct;68(4):1583-9.PMID: 16164635 [PubMed - indexed for MEDLINE]Related articles

Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.

Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H.

Diabetes. 2007 Feb;56(2):363-72. Erratum in: Diabetes. 2007 Mar;56(3):897. Takeya, Masahiro [corrected to Takeya, Motohiro]. PMID: 17259380 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressions of chronic glomerular injuries and TGF-beta 1 production by HGF in attenuation of murine diabetic nephropathy.

Mizuno S, Nakamura T.

Am J Physiol Renal Physiol. 2004 Jan;286(1):F134-43. Epub 2003 Sep 30.PMID: 14519594 [PubMed - indexed for MEDLINE]Related articlesFree article

Knocking out peroxisome proliferator-activated receptor (PPAR) alpha inhibits radiation-induced apoptosis in the mouse kidney through activation of NF-kappaB and increased expression of IAPs.

Zhao W, Iskandar S, Kooshki M, Sharpe JG, Payne V, Robbins ME.

Radiat Res. 2007 May;167(5):581-91.PMID: 17474796 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.

Duhaney TA, Cui L, Rude MK, Lebrasseur NK, Ngoy S, De Silva DS, Siwik DA, Liao R, Sam F.

Hypertension. 2007 May;49(5):1084-94. Epub 2007 Mar 12.PMID: 17353509 [PubMed - indexed for MEDLINE]Related articlesFree article

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy.

Al-Douahji M, Brugarolas J, Brown PA, Stehman-Breen CO, Alpers CE, Shankland SJ.

Kidney Int. 1999 Nov;56(5):1691-9.PMID: 10571777 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of candesartan, an angiotensin II type 1 receptor blocker, on diabetic nephropathy in KK/Ta mice.

Liao J, Kobayashi M, Kanamuru Y, Nakamura S, Makita Y, Funabiki K, Horikoshi S, Tomino Y.

J Nephrol. 2003 Nov-Dec;16(6):841-9.PMID: 14736011 [PubMed - indexed for MEDLINE]Related articles

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.

Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16186390 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.

Lassila M, Seah KK, Allen TJ, Thallas V, Thomas MC, Candido R, Burns WC, Forbes JM, Calkin AC, Cooper ME, Jandeleit-Dahm KA.

J Am Soc Nephrol. 2004 Aug;15(8):2125-38.PMID: 15284298 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin.

Sugden MC, Bulmer K, Gibbons GF, Knight BL, Holness MJ.

Biochem J. 2002 Jun 1;364(Pt 2):361-8.PMID: 12023878 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.

Knauf C, Rieusset J, Foretz M, Cani PD, Uldry M, Hosokawa M, Martinez E, Bringart M, Waget A, Kersten S, Desvergne B, Gremlich S, Wahli W, Seydoux J, Delzenne NM, Thorens B, Burcelin R.

Endocrinology. 2006 Sep;147(9):4067-78. Epub 2006 Jun 15.PMID: 16777972 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats.

Zhao X, Li LY.

Am J Nephrol. 2008;28(4):598-606. Epub 2008 Feb 14.PMID: 18277067 [PubMed - indexed for MEDLINE]Related articles

Decreased longevity and enhancement of age-dependent lesions in mice lacking the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).

Howroyd P, Swanson C, Dunn C, Cattley RC, Corton JC.

Toxicol Pathol. 2004 Sep-Oct;32(5):591-9.PMID: 15603543 [PubMed - indexed for MEDLINE]Related articles

Lack of type VIII collagen in mice ameliorates diabetic nephropathy.

Hopfer U, Hopfer H, Meyer-Schwesinger C, Loeffler I, Fukai N, Olsen BR, Stahl RA, Wolf G.

Diabetes. 2009 Jul;58(7):1672-81. Epub 2009 Apr 28.PMID: 19401424 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice.

Park CW, Kim HW, Ko SH, Lim JH, Ryu GR, Chung HW, Han SW, Shin SJ, Bang BK, Breyer MD, Chang YS.

J Am Soc Nephrol. 2007 Apr;18(4):1227-38. Epub 2007 Mar 14.PMID: 17360951 [PubMed - indexed for MEDLINE]Related articlesFree article

Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.

Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A.

Kidney Int. 2006 Aug;70(3):460-70. Epub 2006 Jun 14.PMID: 16775606 [PubMed - indexed for MEDLINE]Related articles