PubMed

Dose escalation of a curcuminoid formulation.

Lao CD, Ruffin MT 4th, Normolle D, Heath DD, Murray SI, Bailey JM, Boggs ME, Crowell J, Rock CL, Brenner DE.

BMC Complement Altern Med. 2006 Mar 17;6:10.PMID: 16545122 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

Sharma RA, McLelland HR, Hill KA, Ireson CR, Euden SA, Manson MM, Pirmohamed M, Marnett LJ, Gescher AJ, Steward WP.

Clin Cancer Res. 2001 Jul;7(7):1894-900.PMID: 11448902 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics and pharmacodynamics of curcumin.

Sharma RA, Steward WP, Gescher AJ.

Adv Exp Med Biol. 2007;595:453-70. Review.PMID: 17569224 [PubMed - indexed for MEDLINE]Related articles

Curcumin: the story so far.

Sharma RA, Gescher AJ, Steward WP.

Eur J Cancer. 2005 Sep;41(13):1955-68. Review.PMID: 16081279 [PubMed - indexed for MEDLINE]Related articles

Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance.

Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, Marczylo TH, Morgan B, Hemingway D, Plummer SM, Pirmohamed M, Gescher AJ, Steward WP.

Clin Cancer Res. 2004 Oct 15;10(20):6847-54.PMID: 15501961 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects.

Vareed SK, Kakarala M, Ruffin MT, Crowell JA, Normolle DP, Djuric Z, Brenner DE.

Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1411-7.PMID: 18559556 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.

Perkins S, Verschoyle RD, Hill K, Parveen I, Threadgill MD, Sharma RA, Williams ML, Steward WP, Gescher AJ.

Cancer Epidemiol Biomarkers Prev. 2002 Jun;11(6):535-40.PMID: 12050094 [PubMed - indexed for MEDLINE]Related articlesFree article

Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.

Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ.

Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5.PMID: 15668484 [PubMed - indexed for MEDLINE]Related articlesFree article

Curcumin for chemoprevention of colon cancer.

Johnson JJ, Mukhtar H.

Cancer Lett. 2007 Oct 8;255(2):170-81. Epub 2007 Apr 19.PMID: 17448598 [PubMed - indexed for MEDLINE]Related articles

Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.

[No authors listed]

Int J Toxicol. 2007;26 Suppl 1:3-106. Review.PMID: 17365137 [PubMed - indexed for MEDLINE]Related articles

Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine.

Marczylo TH, Verschoyle RD, Cooke DN, Morazzoni P, Steward WP, Gescher AJ.

Cancer Chemother Pharmacol. 2007 Jul;60(2):171-7. Epub 2006 Oct 19.PMID: 17051370 [PubMed - indexed for MEDLINE]Related articles

Clinical studies with curcumin.

Hsu CH, Cheng AL.

Adv Exp Med Biol. 2007;595:471-80. Review.PMID: 17569225 [PubMed - indexed for MEDLINE]Related articles

Open-label, non-randomised, inter-individual dose escalation of ZK 304709 with the evaluation of safety, tolerability, pharmacokinetics, oral bioavailability and orientating efficacy after daily administration in patients with advanced cancer (7 d treatment and 14 d recovery).

Graham JS, Plummer R, McCoy C, Kowal K, Wiesinger H, Detjen K, Calvert H, Wiedenmann B, Cassidy J.

Eur J Cancer. 2008 Oct;44(15):2162-8. Epub 2008 Jul 22.PMID: 18653327 [PubMed - indexed for MEDLINE]Related articles

Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration.

Garcea G, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ, Berry DP.

Br J Cancer. 2004 Mar 8;90(5):1011-5.PMID: 14997198 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ.

Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):105-11.PMID: 11815407 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular orbital basis for yellow curry spice curcumin's prevention of Alzheimer's disease.

Balasubramanian K.

J Agric Food Chem. 2006 May 17;54(10):3512-20.PMID: 19127718 [PubMed - indexed for MEDLINE]Related articles

EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.

Thomas SL, Zhong D, Zhou W, Malik S, Liotta D, Snyder JP, Hamel E, Giannakakou P.

Cell Cycle. 2008 Aug;7(15):2409-17. Epub 2008 Jun 9.PMID: 18682687 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic delivery of curcumin: 21st century solutions for an ancient conundrum.

Bisht S, Maitra A.

Curr Drug Discov Technol. 2009 Sep;6(3):192-9. Epub 2009 Sep 1. Review.PMID: 19496751 [PubMed - indexed for MEDLINE]Related articles

Bioavailability of two single-dose oral formulations of omeprazole 20 mg: an open-label, randomized sequence, two-period crossover comparison in healthy Mexican adult volunteers.

Poo JL, Galán JF, Rosete A, de Lago A, Oliva I, González-de la Parra M, Jiménez P, Burke-Fraga V, Namur S.

Clin Ther. 2008 Apr;30(4):693-9.PMID: 18498918 [PubMed - indexed for MEDLINE]Related articles

Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines.

Anuchapreeda S, Tima S, Duangrat C, Limtrakul P.

Cancer Chemother Pharmacol. 2008 Sep;62(4):585-94. Epub 2007 Nov 23.PMID: 18034345 [PubMed - indexed for MEDLINE]Related articles