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    Results: 1 to 20 of 126

    1.

    A gold standard set of mechanistically diverse enzyme superfamilies.

    Brown SD, Gerlt JA, Seffernick JL, Babbitt PC.

    Genome Biol. 2006;7(1):R8. Epub 2006 Jan 31.

    PMID:
    16507141
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Evolution of function in protein superfamilies, from a structural perspective.

    Todd AE, Orengo CA, Thornton JM.

    J Mol Biol. 2001 Apr 6;307(4):1113-43.

    PMID:
    11286560
    [PubMed - indexed for MEDLINE]
    3.

    Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies.

    Chiang RA, Sali A, Babbitt PC.

    PLoS Comput Biol. 2008 Aug 1;4(8):e1000142.

    PMID:
    18670595
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Superfamily active site templates.

    Meng EC, Polacco BJ, Babbitt PC.

    Proteins. 2004 Jun 1;55(4):962-76.

    PMID:
    15146493
    [PubMed - indexed for MEDLINE]
    5.

    Representing structure-function relationships in mechanistically diverse enzyme superfamilies.

    Pegg SC, Brown S, Ojha S, Huang CC, Ferrin TE, Babbitt PC.

    Pac Symp Biocomput. 2005:358-69.

    PMID:
    15759641
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database.

    Pegg SC, Brown SD, Ojha S, Seffernick J, Meng EC, Morris JH, Chang PJ, Huang CC, Ferrin TE, Babbitt PC.

    Biochemistry. 2006 Feb 28;45(8):2545-55.

    PMID:
    16489747
    [PubMed - indexed for MEDLINE]
    7.

    FLORA: a novel method to predict protein function from structure in diverse superfamilies.

    Redfern OC, Dessailly BH, Dallman TJ, Sillitoe I, Orengo CA.

    PLoS Comput Biol. 2009 Aug;5(8):e1000485. Epub 2009 Aug 28.

    PMID:
    19714201
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Relationships between functional subclasses and information contained in active-site and ligand-binding residues in diverse superfamilies.

    Nagao C, Nagano N, Mizuguchi K.

    Proteins. 2010 Aug 1;78(10):2369-84.

    PMID:
    20544971
    [PubMed - indexed for MEDLINE]
    9.

    Using functional domain composition to predict enzyme family classes.

    Cai YD, Chou KC.

    J Proteome Res. 2005 Jan-Feb;4(1):109-11.

    PMID:
    15707365
    [PubMed - indexed for MEDLINE]
    10.

    Structural diversity of domain superfamilies in the CATH database.

    Reeves GA, Dallman TJ, Redfern OC, Akpor A, Orengo CA.

    J Mol Biol. 2006 Jul 14;360(3):725-41. Epub 2006 Jun 2.

    PMID:
    16780872
    [PubMed - indexed for MEDLINE]
    12.

    Conservation of electrostatic properties within enzyme families and superfamilies.

    Livesay DR, Jambeck P, Rojnuckarin A, Subramaniam S.

    Biochemistry. 2003 Apr 1;42(12):3464-73.

    PMID:
    12653550
    [PubMed - indexed for MEDLINE]
    13.

    Finding evolutionary relations beyond superfamilies: fold-based superfamilies.

    Matsuda K, Nishioka T, Kinoshita K, Kawabata T, Go N.

    Protein Sci. 2003 Oct;12(10):2239-51.

    PMID:
    14500881
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

    Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM.

    BMC Bioinformatics. 2007 Mar 5;8:73.

    PMID:
    17338813
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Clustering of protein domains in the human genome.

    Mayor LR, Fleming KP, Müller A, Balding DJ, Sternberg MJ.

    J Mol Biol. 2004 Jul 23;340(5):991-1004.

    PMID:
    15236962
    [PubMed - indexed for MEDLINE]
    16.

    The cadherin superfamily database.

    Truong K, Ikura M.

    J Struct Funct Genomics. 2002;2(3):135-43.

    PMID:
    12836704
    [PubMed - indexed for MEDLINE]
    17.

    MegaMotifBase: a database of structural motifs in protein families and superfamilies.

    Pugalenthi G, Suganthan PN, Sowdhamini R, Chakrabarti S.

    Nucleic Acids Res. 2008 Jan;36(Database issue):D218-21. Epub 2007 Oct 11.

    PMID:
    17933773
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Evolutionary genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes.

    Burroughs AM, Allen KN, Dunaway-Mariano D, Aravind L.

    J Mol Biol. 2006 Sep 1;361(5):1003-34. Epub 2006 Jul 7.

    PMID:
    16889794
    [PubMed - indexed for MEDLINE]
    19.

    A Protein Classification Benchmark collection for machine learning.

    Sonego P, Pacurar M, Dhir S, Kertész-Farkas A, Kocsor A, Gáspári Z, Leunissen JA, Pongor S.

    Nucleic Acids Res. 2007 Jan;35(Database issue):D232-6. Epub 2006 Nov 16.

    PMID:
    17142240
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin.

    Almén MS, Nordström KJ, Fredriksson R, Schiöth HB.

    BMC Biol. 2009 Aug 13;7:50.

    PMID:
    19678920
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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