PubMed

IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.

Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR.

Diabetes. 2006 Mar;55(3):785-91.PMID: 16505244 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552. PMID: 11723060 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.

Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM.

J Clin Endocrinol Metab. 2002 Jan;87(1):226-34.PMID: 11788651 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling.

Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H, Christ-Roberts CY, Mandarino LJ.

Endocrinology. 2007 Oct;148(10):4895-905. Epub 2007 Jul 19.PMID: 17640984 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.

Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.

J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients. Dose-response effects of insulin on glucose turnover.

Christiansen E, Vestergaard H, Tibell A, Hother-Nielsen O, Holst JJ, Pedersen O, Madsbad S.

Diabetes. 1996 Sep;45(9):1267-75.PMID: 8772733 [PubMed - indexed for MEDLINE]Related articles

Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Akt-kinase in human skeletal muscle.

Del Aguila LF, Krishnan RK, Ulbrecht JS, Farrell PA, Correll PH, Lang CH, Zierath JR, Kirwan JP.

Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E206-12.PMID: 10893341 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

Frøsig C, Rose AJ, Treebak JT, Kiens B, Richter EA, Wojtaszewski JF.

Diabetes. 2007 Aug;56(8):2093-102. Epub 2007 May 18.PMID: 17513702 [PubMed - indexed for MEDLINE]Related articlesFree article

C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

D'Alessandris C, Lauro R, Presta I, Sesti G.

Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.

Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG.

Life Sci. 2005 Oct 28;77(24):3068-77. Epub 2005 Jun 27.PMID: 15982669 [PubMed - indexed for MEDLINE]Related articles

Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.

Hennige AM, Stefan N, Kapp K, Lehmann R, Weigert C, Beck A, Moeschel K, Mushack J, Schleicher E, Häring HU.

FASEB J. 2006 Jun;20(8):1206-8. Epub 2006 Apr 12.PMID: 16611834 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

Howlett KF, Sakamoto K, Yu H, Goodyear LJ, Hargreaves M.

Metabolism. 2006 Aug;55(8):1046-52.PMID: 16839840 [PubMed - indexed for MEDLINE]Related articles

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes.

Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB.

J Clin Invest. 1999 Sep;104(6):733-41.PMID: 10491408 [PubMed - indexed for MEDLINE]Related articlesFree article

Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.

Park E, Wong V, Guan X, Oprescu AI, Giacca A.

J Endocrinol. 2007 Nov;195(2):323-31.PMID: 17951543 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle.

Dokken BB, Sloniger JA, Henriksen EJ.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1188-94. Epub 2005 Jan 25.PMID: 15671078 [PubMed - indexed for MEDLINE]Related articlesFree article

Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes.

Meyer MM, Levin K, Grimmsmann T, Perwitz N, Eirich A, Beck-Nielsen H, Klein HH.

Diabetes. 2002 Sep;51(9):2691-7.PMID: 12196460 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats.

Giorgino F, Logoluso F, Davalli AM, Napoli R, Laviola L, Hirshman MF, Horton ES, Weir GC, Smith RJ.

Diabetes. 1999 Apr;48(4):801-12.PMID: 10102697 [PubMed - indexed for MEDLINE]Related articlesFree article

Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.

Thong FS, Derave W, Kiens B, Graham TE, Ursø B, Wojtaszewski JF, Hansen BF, Richter EA.

Diabetes. 2002 Mar;51(3):583-90.PMID: 11872654 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.

Rojas FA, Hirata AE, Saad MJ.

Mol Cell Endocrinol. 2001 Oct 25;183(1-2):63-9.PMID: 11604226 [PubMed - indexed for MEDLINE]Related articles