PubMed

MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.

Ye DZ, Tai MH, Linning KD, Szabo C, Olson LK.

Diabetes. 2006 Mar;55(3):742-50.PMID: 16505238 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated glucose attenuates human insulin gene promoter activity in INS-1 pancreatic beta-cells via reduced nuclear factor binding to the A5/core and Z element.

Pino MF, Ye DZ, Linning KD, Green CD, Wicksteed B, Poitout V, Olson LK.

Mol Endocrinol. 2005 May;19(5):1343-60. Epub 2005 Jan 13.PMID: 15650027 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells.

Harmon JS, Stein R, Robertson RP.

J Biol Chem. 2005 Mar 25;280(12):11107-13. Epub 2005 Jan 20.PMID: 15664999 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of inhibitors of poly(ADP-ribose) polymerase in protecting rat RINm5F cell line against free fatty acid-induced apoptosis.

Mao X, Wang S, Pan Y, He B, Chen J, Jiang H, Zeng Q, Xu X.

Exp Clin Endocrinol Diabetes. 2009 Jun;117(6):274-82. Epub 2009 Jun 9.PMID: 19513971 [PubMed - indexed for MEDLINE]Related articles

Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter.

Docherty HM, Hay CW, Ferguson LA, Barrow J, Durward E, Docherty K.

Biochem J. 2005 Aug 1;389(Pt 3):813-20.PMID: 15862113 [PubMed - indexed for MEDLINE]Related articlesFree article

MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3.

Han SI, Aramata S, Yasuda K, Kataoka K.

Mol Cell Biol. 2007 Oct;27(19):6593-605. Epub 2007 Aug 6.PMID: 17682063 [PubMed - indexed for MEDLINE]Related articlesFree article

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.

Kataoka K, Han SI, Shioda S, Hirai M, Nishizawa M, Handa H.

J Biol Chem. 2002 Dec 20;277(51):49903-10. Epub 2002 Oct 3.PMID: 12368292 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles and regulation of transcription factor MafA in islet beta-cells.

Aramata S, Han SI, Kataoka K.

Endocr J. 2007 Dec;54(5):659-66. Epub 2007 Aug 30. Review.PMID: 17785922 [PubMed - indexed for MEDLINE]Related articlesFree article

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R.

Mol Cell Biol. 2006 Aug;26(15):5735-43.PMID: 16847327 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription factor cycling on the insulin promoter.

Barrow J, Hay CW, Ferguson LA, Docherty HM, Docherty K.

FEBS Lett. 2006 Jan 23;580(2):711-5. Epub 2005 Dec 28.PMID: 16412423 [PubMed - indexed for MEDLINE]Related articles

MafA regulates expression of genes important to islet beta-cell function.

Matsuoka TA, Kaneto H, Stein R, Miyatsuka T, Kawamori D, Henderson E, Kojima I, Matsuhisa M, Hori M, Yamasaki Y.

Mol Endocrinol. 2007 Nov;21(11):2764-74. Epub 2007 Jul 17.PMID: 17636040 [PubMed - indexed for MEDLINE]Related articlesFree article

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells.

Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R.

Mol Cell Biol. 2003 Sep;23(17):6049-62.PMID: 12917329 [PubMed - indexed for MEDLINE]Related articlesFree article

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.

Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A.

Dev Biol. 2006 May 15;293(2):526-39. Epub 2006 Apr 3.PMID: 16580660 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination of MafA, PDX-1 and NeuroD is a useful tool to efficiently induce insulin-producing surrogate beta-cells.

Kaneto H, Matsuoka TA, Katakami N, Matsuhisa M.

Curr Med Chem. 2009;16(24):3144-51. Review.PMID: 19689288 [PubMed - indexed for MEDLINE]Related articles

Role of PDX-1 and MafA as a potential therapeutic target for diabetes.

Kaneto H, Miyatsuka T, Fujitani Y, Noguchi H, Song KH, Yoon KH, Matsuoka TA.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S127-37. Epub 2007 Apr 20. Review.PMID: 17449132 [PubMed - indexed for MEDLINE]Related articles

The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription.

Zhao L, Guo M, Matsuoka TA, Hagman DK, Parazzoli SD, Poitout V, Stein R.

J Biol Chem. 2005 Mar 25;280(12):11887-94. Epub 2005 Jan 20.PMID: 15665000 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells.

Oetjen E, Blume R, Cierny I, Schlag C, Kutschenko A, Krätzner R, Stein R, Knepel W.

Diabetologia. 2007 Aug;50(8):1678-87. Epub 2007 Jun 22.PMID: 17583797 [PubMed - indexed for MEDLINE]Related articles

Role of MafA in pancreatic beta-cells.

Kaneto H, Matsuoka TA, Kawashima S, Yamamoto K, Kato K, Miyatsuka T, Katakami N, Matsuhisa M.

Adv Drug Deliv Rev. 2009 Jul 2;61(7-8):489-96. Epub 2009 Apr 22. Review.PMID: 19393272 [PubMed - indexed for MEDLINE]Related articles

Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter.

Kajihara M, Sone H, Amemiya M, Katoh Y, Isogai M, Shimano H, Yamada N, Takahashi S.

Biochem Biophys Res Commun. 2003 Dec 19;312(3):831-42.PMID: 14680841 [PubMed - indexed for MEDLINE]Related articles

PDX-1 functions as a master factor in the pancreas.

Kaneto H, Matsuoka TA, Miyatsuka T, Kawamori D, Katakami N, Yamasaki Y, Matsuhisa M.

Front Biosci. 2008 May 1;13:6406-20. Review.PMID: 18508668 [PubMed - indexed for MEDLINE]Related articles