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    Results: 1 to 20 of 478

    1.

    Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight.

    Bjursell M, Gerdin AK, Ploj K, Svensson D, Svensson L, Oscarsson J, Snaith M, Törnell J, Bohlooly-Y M.

    Diabetes. 2006 Mar;55(3):725-33.PMID: 16505236 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.

    Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E.

    Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. Epub 2003 Aug 1.PMID: 12897241 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Increases in melanin-concentrating hormone and MCH receptor levels in the hypothalamus of dietary-obese rats.

    Elliott JC, Harrold JA, Brodin P, Enquist K, Bäckman A, Byström M, Lindgren K, King P, Williams G.

    Brain Res Mol Brain Res. 2004 Sep 28;128(2):150-9.PMID: 15363890 [PubMed - indexed for MEDLINE]Related articles

    4.

    Effects of leptin on melanin-concentrating hormone expression in the brain of lean and obese Lep(ob)/Lep(ob) mice.

    Huang Q, Viale A, Picard F, Nahon J, Richard D.

    Neuroendocrinology. 1999 Mar;69(3):145-53. Erratum in: Neuroendocrinology 1999 Aug;70(2):92. PMID: 10087446 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.

    Kowalski TJ, Spar BD, Weig B, Farley C, Cook J, Ghibaudi L, Fried S, O'Neill K, Del Vecchio RA, McBriar M, Guzik H, Clader J, Hawes BE, Hwa J.

    Eur J Pharmacol. 2006 Mar 27;535(1-3):182-91. Epub 2006 Mar 13.PMID: 16540104 [PubMed - indexed for MEDLINE]Related articles

    6.

    Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity.

    Chen Y, Hu C, Hsu CK, Zhang Q, Bi C, Asnicar M, Hsiung HM, Fox N, Slieker LJ, Yang DD, Heiman ML, Shi Y.

    Endocrinology. 2002 Jul;143(7):2469-77.PMID: 12072376 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.

    Sun Y, Asnicar M, Saha PK, Chan L, Smith RG.

    Cell Metab. 2006 May;3(5):379-86.PMID: 16679295 [PubMed - indexed for MEDLINE]Related articles

    8.

    Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c.

    Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR.

    Diabetes. 2006 Jul;55(7):2032-41.PMID: 16804073 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance.

    Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E.

    J Clin Invest. 2001 Feb;107(3):379-86.PMID: 11160162 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Leptin deficiency per se dictates body composition and insulin action in ob/ob mice.

    van den Hoek AM, Teusink B, Voshol PJ, Havekes LM, Romijn JA, Pijl H.

    J Neuroendocrinol. 2008 Jan;20(1):120-7.PMID: 18081560 [PubMed - indexed for MEDLINE]Related articles

    11.

    Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity.

    Astrand A, Bohlooly-Y M, Larsdotter S, Mahlapuu M, Andersén H, Tornell J, Ohlsson C, Snaith M, Morgan DG.

    Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R749-58. Epub 2004 May 6.PMID: 15130877 [PubMed - indexed for MEDLINE]Related articles

    12.

    Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons.

    Alon T, Friedman JM.

    J Neurosci. 2006 Jan 11;26(2):389-97.PMID: 16407534 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice.

    Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM.

    Biochem Biophys Res Commun. 2009 Mar 20;380(4):818-22. Epub 2009 Feb 5.PMID: 19338759 [PubMed - indexed for MEDLINE]Related articles

    14.

    Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.

    Trevaskis JL, Butler AA.

    Endocrinology. 2005 Oct;146(10):4257-65. Epub 2005 Jun 30. Erratum in: Endocrinology. 2005 Dec;146(12):5387. PMID: 15994342 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice.

    Lalonde J, Samson P, Poulin S, Deshaies Y, Richard D.

    Physiol Behav. 2004 Jan;80(4):415-20.PMID: 14741225 [PubMed - indexed for MEDLINE]Related articles

    16.

    Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice.

    Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD.

    Diabetes. 2007 May;56(5):1228-39. Epub 2007 Mar 16.PMID: 17369521 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity.

    Phan LK, Chung WK, Leibel RL.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E611-20. Epub 2006 Apr 25.PMID: 16638826 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

    Uysal KT, Scheja L, Wiesbrock SM, Bonner-Weir S, Hotamisligil GS.

    Endocrinology. 2000 Sep;141(9):3388-96.PMID: 10965911 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility.

    Klebanov S, Astle CM, DeSimone O, Ablamunits V, Harrison DE.

    J Endocrinol. 2005 Jul;186(1):203-11.PMID: 16002549 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Regulation of energy balance by leptin.

    Hamann A, Matthaei S.

    Exp Clin Endocrinol Diabetes. 1996;104(4):293-300. Review.PMID: 8886745 [PubMed - indexed for MEDLINE]Related articles

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