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    Results: 1 to 20 of 216

    1.

    Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance.

    Shi H, Cave B, Inouye K, Bjørbaek C, Flier JS.

    Diabetes. 2006 Mar;55(3):699-707.PMID: 16505233 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.

    Shi H, Tzameli I, Bjørbaek C, Flier JS.

    J Biol Chem. 2004 Aug 13;279(33):34733-40. Epub 2004 Jun 4.PMID: 15181014 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Chronic tumor necrosis factor-alpha treatment causes insulin resistance via insulin receptor substrate-1 serine phosphorylation and suppressor of cytokine signaling-3 induction in 3T3-L1 adipocytes.

    Ishizuka K, Usui I, Kanatani Y, Bukhari A, He J, Fujisaka S, Yamazaki Y, Suzuki H, Hiratani K, Ishiki M, Iwata M, Urakaze M, Haruta T, Kobayashi M.

    Endocrinology. 2007 Jun;148(6):2994-3003. Epub 2007 Mar 22.PMID: 17379643 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression.

    Kanatani Y, Usui I, Ishizuka K, Bukhari A, Fujisaka S, Urakaze M, Haruta T, Kishimoto T, Naka T, Kobayashi M.

    Diabetes. 2007 Mar;56(3):795-803.PMID: 17327450 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.

    Ueki K, Kondo T, Kahn CR.

    Mol Cell Biol. 2004 Jun;24(12):5434-46. Erratum in: Mol Cell Biol. 2005 Oct;25(19):8762. PMID: 15169905 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

    Emanuelli B, Peraldi P, Filloux C, Chavey C, Freidinger K, Hilton DJ, Hotamisligil GS, Van Obberghen E.

    J Biol Chem. 2001 Dec 21;276(51):47944-9. Epub 2001 Oct 16.PMID: 11604392 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Whole-body insulin resistance in the absence of obesity in FVB mice with overexpression of Dgat1 in adipose tissue.

    Chen N, Liu L, Zhang Y, Ginsberg HN, Yu YH.

    Diabetes. 2005 Dec;54(12):3379-86.PMID: 16306352 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Amelioration of insulin resistance in streptozotocin diabetic mice by transgenic overexpression of GLUT4 driven by an adipose-specific promoter.

    Tozzo E, Gnudi L, Kahn BB.

    Endocrinology. 1997 Apr;138(4):1604-11.PMID: 9075721 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes.

    Lagathu C, Yvan-Charvet L, Bastard JP, Maachi M, Quignard-Boulangé A, Capeau J, Caron M.

    Diabetologia. 2006 Sep;49(9):2162-73. Epub 2006 Jul 25.PMID: 16865359 [PubMed - indexed for MEDLINE]Related articles

    10.

    PRL receptor-mediated effects in female mouse adipocytes: PRL induces suppressors of cytokine signaling expression and suppresses insulin-induced leptin production in adipocytes in vitro.

    Ling C, Billig H.

    Endocrinology. 2001 Nov;142(11):4880-90.PMID: 11606456 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/Jng.

    Wang Y, Nishina PM, Naggert JK.

    J Endocrinol. 2009 Oct;203(1):65-74. Epub 2009 Jul 8.PMID: 19587264 [PubMed - indexed for MEDLINE]Related articles

    12.

    Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy.

    Sevillano J, de Castro J, Bocos C, Herrera E, Ramos MP.

    Endocrinology. 2007 Dec;148(12):5933-42. Epub 2007 Sep 6.PMID: 17823255 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Exclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistance.

    Xu H, Hirosumi J, Uysal KT, Guler AD, Hotamisligil GS.

    Endocrinology. 2002 Apr;143(4):1502-11.PMID: 11897709 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.

    Sabio G, Das M, Mora A, Zhang Z, Jun JY, Ko HJ, Barrett T, Kim JK, Davis RJ.

    Science. 2008 Dec 5;322(5907):1539-43.PMID: 19056984 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.

    Kawaguchi T, Yoshida T, Harada M, Hisamoto T, Nagao Y, Ide T, Taniguchi E, Kumemura H, Hanada S, Maeyama M, Baba S, Koga H, Kumashiro R, Ueno T, Ogata H, Yoshimura A, Sata M.

    Am J Pathol. 2004 Nov;165(5):1499-508.PMID: 15509521 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

    Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

    J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.PMID: 16446356 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats.

    Jia X, Wu L.

    Mol Cell Biochem. 2007 Dec;306(1-2):133-9. Epub 2007 Jul 28.PMID: 17660951 [PubMed - indexed for MEDLINE]Related articles

    18.

    Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.

    Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS.

    J Clin Invest. 2008 Jul;118(7):2640-50.PMID: 18551191 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.

    Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.

    J Biol Chem. 2006 Sep 8;281(36):26602-14. Epub 2006 Jun 29.PMID: 16809344 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.

    Lorenzo M, Fernández-Veledo S, Vila-Bedmar R, Garcia-Guerra L, De Alvaro C, Nieto-Vazquez I.

    J Anim Sci. 2008 Apr;86(14 Suppl):E94-104. Epub 2007 Oct 16. Review.PMID: 17940160 [PubMed - indexed for MEDLINE]Related articlesFree article

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