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    Results: 1 to 20 of 348

    1.

    Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.

    Alao JP, Stavropoulou AV, Lam EW, Coombes RC, Vigushin DM.

    Mol Cancer. 2006 Feb 20;5:8.PMID: 16504004 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines.

    Alao JP, Gamble SC, Stavropoulou AV, Pomeranz KM, Lam EW, Coombes RC, Vigushin DM.

    Mol Cancer. 2006 Feb 17;5:7.PMID: 16503970 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines.

    Alao JP, Lam EW, Ali S, Buluwela L, Bordogna W, Lockey P, Varshochi R, Stavropoulou AV, Coombes RC, Vigushin DM.

    Clin Cancer Res. 2004 Dec 1;10(23):8094-104.PMID: 15585645 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1.

    Zhou Q, Melkoumian ZK, Lucktong A, Moniwa M, Davie JR, Strobl JS.

    J Biol Chem. 2000 Nov 10;275(45):35256-63.PMID: 10938272 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells.

    Alao JP, Stavropoulou AV, Lam EW, Coombes RC.

    Mol Cancer. 2006 Oct 3;5:40.PMID: 17018141 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.

    Dong J, Peng J, Zhang H, Mondesire WH, Jian W, Mills GB, Hung MC, Meric-Bernstam F.

    Cancer Res. 2005 Mar 1;65(5):1961-72.PMID: 15753396 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin-like growth factor I triggers nuclear accumulation of cyclin D1 in MCF-7S breast cancer cells.

    Hamelers IH, van Schaik RF, Sipkema J, Sussenbach JS, Steenbergh PH.

    J Biol Chem. 2002 Dec 6;277(49):47645-52. Epub 2002 Oct 2.PMID: 12364325 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding.

    Hu J, Colburn NH.

    Mol Cancer Res. 2005 Feb;3(2):100-9.PMID: 15755876 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.

    Wei S, Yang HC, Chuang HC, Yang J, Kulp SK, Lu PJ, Lai MD, Chen CS.

    J Biol Chem. 2008 Sep 26;283(39):26759-70. Epub 2008 Jul 23.PMID: 18650423 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase.

    Kim YB, Lee KH, Sugita K, Yoshida M, Horinouchi S.

    Oncogene. 1999 Apr 15;18(15):2461-70.PMID: 10229197 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.

    Zhang Q, Tian L, Mansouri A, Korapati AL, Johnson TJ, Claret FX.

    FEBS Lett. 2005 Jul 18;579(18):3932-40.PMID: 15996662 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells.

    Qin C, Burghardt R, Smith R, Wormke M, Stewart J, Safe S.

    Cancer Res. 2003 Mar 1;63(5):958-64.PMID: 12615709 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    A plant oxylipin, 12-oxo-phytodienoic acid, inhibits proliferation of human breast cancer cells by targeting cyclin D1.

    Altiok N, Mezzadra H, Patel P, Koyuturk M, Altiok S.

    Breast Cancer Res Treat. 2008 May;109(2):315-23. Epub 2007 Jul 19.PMID: 17638069 [PubMed - indexed for MEDLINE]Related articles

    14.

    Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells.

    Park H, Lee YJ, Kim TH, Lee J, Yoon S, Choi WS, Myung CS, Kim HS.

    Int J Mol Med. 2008 Nov;22(5):605-11.PMID: 18949380 [PubMed - indexed for MEDLINE]Related articles

    15.

    Histone deacetylase inhibitor SAHA induces ERalpha degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling.

    Yi X, Wei W, Wang SY, Du ZY, Xu YJ, Yu XD.

    Biochem Pharmacol. 2008 May 1;75(9):1697-705. Epub 2007 Nov 9.PMID: 18342836 [PubMed - indexed for MEDLINE]Related articles

    16.

    Nuclear factor-kappaB p65 small interfering RNA or proteasome inhibitor bortezomib sensitizes head and neck squamous cell carcinomas to classic histone deacetylase inhibitors and novel histone deacetylase inhibitor PXD101.

    Duan J, Friedman J, Nottingham L, Chen Z, Ara G, Van Waes C.

    Mol Cancer Ther. 2007 Jan;6(1):37-50.PMID: 17237265 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrest.

    Luo H, Zhang J, Dastvan F, Yanagawa B, Reidy MA, Zhang HM, Yang D, Wilson JE, McManus BM.

    J Virol. 2003 Jan;77(1):1-9.PMID: 12477805 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation.

    Zhang M, Xie R, Hou W, Wang B, Shen R, Wang X, Wang Q, Zhu T, Jonason JH, Chen D.

    J Cell Sci. 2009 May 1;122(Pt 9):1382-9. Epub 2009 Apr 7.PMID: 19351720 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mechanism of cell cycle regulation by FIP200 in human breast cancer cells.

    Melkoumian ZK, Peng X, Gan B, Wu X, Guan JL.

    Cancer Res. 2005 Aug 1;65(15):6676-84.PMID: 16061648 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Trichostatin and leptomycin. Inhibition of histone deacetylation and signal-dependent nuclear export.

    Yoshida M, Horinouchi S.

    Ann N Y Acad Sci. 1999;886:23-36. Review.PMID: 10667200 [PubMed - indexed for MEDLINE]Related articles

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