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Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor.

Chen J, Raymond K.

Ann Clin Microbiol Antimicrob. 2006 Feb 15;5:3. Review.PMID: 16480505 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinically significant interactions with drugs used in the treatment of tuberculosis.

Yew WW.

Drug Saf. 2002;25(2):111-33. Review.PMID: 11888353 [PubMed - indexed for MEDLINE]Related articles

Inducing properties of rifampicin and rifabutin for selected enzyme activities of the cytochrome P-450 and UDP-glucuronosyltransferase superfamilies in female rat liver.

Oesch F, Arand M, Benedetti MS, Castelli MG, Dostert P.

J Antimicrob Chemother. 1996 Jun;37(6):1111-9.PMID: 8836814 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetic drug interactions with rifampicin.

Venkatesan K.

Clin Pharmacokinet. 1992 Jan;22(1):47-65. Review.PMID: 1559307 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms of cytochrome p450 induction: potential for drug-drug interactions.

Jana S, Paliwal J.

Curr Protein Pept Sci. 2007 Dec;8(6):619-28. Review.PMID: 18220847 [PubMed - indexed for MEDLINE]Related articles

Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR.

Ott M, Fricker G, Bauer B.

J Pharmacol Exp Ther. 2009 Apr;329(1):141-9. Epub 2009 Jan 15.PMID: 19147857 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic interactions with rifampicin : clinical relevance.

Niemi M, Backman JT, Fromm MF, Neuvonen PJ, Kivistö KT.

Clin Pharmacokinet. 2003;42(9):819-50. Review.PMID: 12882588 [PubMed - indexed for MEDLINE]Related articles

Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro.

Haughton EL, Tucker SJ, Marek CJ, Durward E, Leel V, Bascal Z, Monaghan T, Koruth M, Collie-Duguid E, Mann DA, Trim JE, Wright MC.

Gastroenterology. 2006 Jul;131(1):194-209.PMID: 16831602 [PubMed - indexed for MEDLINE]Related articles

Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig.

Nannelli A, Chirulli V, Longo V, Gervasi PG.

Toxicology. 2008 Oct 30;252(1-3):105-12. Epub 2008 Aug 22.PMID: 18786598 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetics and pharmacodynamics of drug interactions involving rifampicin, rifabutin and antimalarial drugs.

Sousa M, Pozniak A, Boffito M.

J Antimicrob Chemother. 2008 Nov;62(5):872-8. Epub 2008 Aug 18. Review.PMID: 18713760 [PubMed - indexed for MEDLINE]Related articlesFree article

Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.

Fang HL, Strom SC, Ellis E, Duanmu Z, Fu J, Duniec-Dmuchowski Z, Falany CN, Falany JL, Kocarek TA, Runge-Morris M.

J Pharmacol Exp Ther. 2007 Nov;323(2):586-98. Epub 2007 Aug 8.PMID: 17687072 [PubMed - indexed for MEDLINE]Related articlesFree article

A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.

Ma X, Cheung C, Krausz KW, Shah YM, Wang T, Idle JR, Gonzalez FJ.

Drug Metab Dispos. 2008 Dec;36(12):2506-12. Epub 2008 Sep 17.PMID: 18799805 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of rifampicin on efavirenz pharmacokinetics in HIV-infected children with tuberculosis.

Ren Y, Nuttall JJ, Eley BS, Meyers TM, Smith PJ, Maartens G, McIlleron HM.

J Acquir Immune Defic Syndr. 2009 Apr 15;50(5):439-43.PMID: 19223781 [PubMed - indexed for MEDLINE]Related articles

Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

Svecova L, Vrzal R, Burysek L, Anzenbacherova E, Cerveny L, Grim J, Trejtnar F, Kunes J, Pour M, Staud F, Anzenbacher P, Dvorak Z, Pavek P.

Drug Metab Dispos. 2008 Feb;36(2):339-48. Epub 2007 Nov 12.PMID: 17998298 [PubMed - indexed for MEDLINE]Related articlesFree article

Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.

Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.

Drug Metab Dispos. 2007 Jul;35(7):1032-41. Epub 2007 Mar 28.PMID: 17392393 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of a concomitant single oral dose of rifampicin on the pharmacokinetics of pravastatin in a two-phase, randomized, single-blind, placebo-controlled, crossover study in healthy Chinese male subjects.

Deng S, Chen XP, Cao D, Yin T, Dai ZY, Luo J, Tang L, Li YJ.

Clin Ther. 2009 Jun;31(6):1256-63.PMID: 19695392 [PubMed - indexed for MEDLINE]Related articles

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

Gui C, Miao Y, Thompson L, Wahlgren B, Mock M, Stieger B, Hagenbuch B.

Eur J Pharmacol. 2008 Apr 14;584(1):57-65. Epub 2008 Feb 8.PMID: 18321482 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.

Bauer B, Yang X, Hartz AM, Olson ER, Zhao R, Kalvass JC, Pollack GM, Miller DS.

Mol Pharmacol. 2006 Oct;70(4):1212-9. Epub 2006 Jul 12.PMID: 16837625 [PubMed - indexed for MEDLINE]Related articlesFree article

Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor.

Köhle C, Bock KW.

Biochem Pharmacol. 2009 Feb 15;77(4):689-99. Epub 2008 Jul 5. Review.PMID: 18606396 [PubMed - indexed for MEDLINE]Related articles

[The induction of CYP3A regulated by pregnane X receptor and its significance in drug metabolism]

Wang YG, Wang SQ, Gao Y.

Yao Xue Xue Bao. 2006 Jan;41(1):1-6. Review. Chinese. No abstract available. PMID: 16683519 [PubMed - indexed for MEDLINE]Related articles