PubMed

Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator.

Heynekamp JJ, Hunsaker LA, Vander Jagt TA, Deck LM, Vander Jagt DL.

BMC Chem Biol. 2006 Feb 8;6:1.PMID: 16466576 [PubMed]Related articlesFree article

Evolving role of uPA/uPAR system in human cancers.

Dass K, Ahmad A, Azmi AS, Sarkar SH, Sarkar FH.

Cancer Treat Rev. 2008 Apr;34(2):122-36. Epub 2007 Dec 26. Review.PMID: 18162327 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel inhibitor of urokinase-type plasminogen activator.

Zhu M, Gokhale VM, Szabo L, Munoz RM, Baek H, Bashyam S, Hurley LH, Von Hoff DD, Han H.

Mol Cancer Ther. 2007 Apr;6(4):1348-56.PMID: 17431113 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.

Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.

Clin Cancer Res. 2007 Jul 15;13(14):4051-60.PMID: 17634529 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation.

Tarui T, Akakura N, Majumdar M, Andronicos N, Takagi J, Mazar AP, Bdeir K, Kuo A, Yarovoi SV, Cines DB, Takada Y.

Thromb Haemost. 2006 Mar;95(3):524-34.PMID: 16525582 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells.

Whitley BR, Beaulieu LM, Carter JC, Church FC.

Gynecol Oncol. 2007 Feb;104(2):470-9. Epub 2006 Oct 30.PMID: 17070899 [PubMed - indexed for MEDLINE]Related articles

Quantitative RT-PCR assays for the determination of urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 mRNA in primary tumor tissue of breast cancer patients: comparison to antigen quantification by ELISA.

Biermann JC, Holzscheiter L, Kotzsch M, Luther T, Kiechle-Bahat M, Sweep FC, Span PN, Schmitt M, Magdolen V.

Int J Mol Med. 2008 Feb;21(2):251-9.PMID: 18204793 [PubMed - indexed for MEDLINE]Related articles

Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system.

Yin S, Lockett J, Meng Y, Biliran H Jr, Blouse GE, Li X, Reddy N, Zhao Z, Lin X, Anagli J, Cher ML, Sheng S.

Cancer Res. 2006 Apr 15;66(8):4173-81.PMID: 16618739 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover.

Dong Z, Saliganan AD, Meng H, Nabha SM, Sabbota AL, Sheng S, Bonfil RD, Cher ML.

Neoplasia. 2008 May;10(5):439-49.PMID: 18472961 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity.

Stillfried GE, Saunders DN, Ranson M.

Breast Cancer Res. 2007;9(1):R14.PMID: 17257442 [PubMed - indexed for MEDLINE]Related articlesFree article

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.

Merchan JR, Tang J, Hu G, Lin Y, Mutter W, Tong C, Karumanchi SA, Russell SJ, Sukhatme VP.

J Natl Cancer Inst. 2006 Jun 7;98(11):756-64.PMID: 16757700 [PubMed - indexed for MEDLINE]Related articlesFree article

Pro-urokinase-type plasminogen activator is a substrate for hepsin.

Moran P, Li W, Fan B, Vij R, Eigenbrot C, Kirchhofer D.

J Biol Chem. 2006 Oct 13;281(41):30439-46. Epub 2006 Aug 14.PMID: 16908524 [PubMed - indexed for MEDLINE]Related articlesFree article

Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation.

Madsen MA, Deryugina EI, Niessen S, Cravatt BF, Quigley JP.

J Biol Chem. 2006 Jun 9;281(23):15997-6005. Epub 2006 Apr 12.PMID: 16611636 [PubMed - indexed for MEDLINE]Related articlesFree article

Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors.

Gutova M, Najbauer J, Frank RT, Kendall SE, Gevorgyan A, Metz MZ, Guevorkian M, Edmiston M, Zhao D, Glackin CA, Kim SU, Aboody KS.

Stem Cells. 2008 Jun;26(6):1406-13. Epub 2008 Apr 10.PMID: 18403751 [PubMed - indexed for MEDLINE]Related articlesFree article

Urokinase-type plasminogen activator.

Crippa MP.

Int J Biochem Cell Biol. 2007;39(4):690-4. Epub 2006 Oct 21. Review.PMID: 17118695 [PubMed - indexed for MEDLINE]Related articles

Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1.

Zhao G, Yuan C, Wind T, Huang Z, Andreasen PA, Huang M.

J Struct Biol. 2007 Oct;160(1):1-10. Epub 2007 Jun 20.PMID: 17692534 [PubMed - indexed for MEDLINE]Related articles

Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis.

Offersen BV, Pfeiffer P, Andreasen P, Overgaard J.

Lung Cancer. 2007 Apr;56(1):43-50. Epub 2007 Jan 17.PMID: 17207889 [PubMed - indexed for MEDLINE]Related articles

Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis.

Skeldal S, Larsen JV, Pedersen KE, Petersen HH, Egelund R, Christensen A, Jensen JK, Gliemann J, Andreasen PA.

FEBS J. 2006 Nov;273(22):5143-59. Epub 2006 Oct 17.PMID: 17042782 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of kringle fragment of urokinase-induced vascular smooth muscle cell migration.

Roztocil E, Nicholl SM, Davies MG.

J Surg Res. 2007 Jul;141(1):83-90.PMID: 17574041 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion.

Quemener C, Gabison EE, Naïmi B, Lescaille G, Bougatef F, Podgorniak MP, Labarchède G, Lebbé C, Calvo F, Menashi S, Mourah S.

Cancer Res. 2007 Jan 1;67(1):9-15.PMID: 17210677 [PubMed - indexed for MEDLINE]Related articlesFree article