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    Results: 1 to 20 of 147

    1.

    Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients.

    Ostenson CG, Gaisano H, Sheu L, Tibell A, Bartfai T.

    Diabetes. 2006 Feb;55(2):435-40.PMID: 16443778 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.

    Nagamatsu S, Nakamichi Y, Yamamura C, Matsushima S, Watanabe T, Ozawa S, Furukawa H, Ishida H.

    Diabetes. 1999 Dec;48(12):2367-73.PMID: 10580425 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment.

    Gaisano HY, Ostenson CG, Sheu L, Wheeler MB, Efendic S.

    Endocrinology. 2002 Nov;143(11):4218-26.PMID: 12399415 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effects of palmitate on insulin secretion and exocytotic proteins in islets of diabetic Goto-Kakizaki rats.

    Ostenson CG, Chen J, Sheu L, Gaisano HY.

    Pancreas. 2007 Apr;34(3):359-63.PMID: 17414060 [PubMed - indexed for MEDLINE]Related articles

    5.

    Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets.

    Cunha DA, Amaral ME, Carvalho CP, Collares-Buzato CB, Carneiro EM, Boschero AC.

    Biol Res. 2006;39(3):555-66. Epub 2006 Nov 7.PMID: 17106586 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Targeting of voltage-gated K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic alpha-cells: effects on glucagon stimulus-secretion coupling.

    Xia F, Leung YM, Gaisano G, Gao X, Chen Y, Fox JE, Bhattacharjee A, Wheeler MB, Gaisano HY, Tsushima RG.

    Endocrinology. 2007 May;148(5):2157-67. Epub 2007 Feb 15.PMID: 17303668 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Down-regulated expression of exocytotic proteins in pancreatic islets of diabetic GK rats.

    Zhang W, Khan A, Ostenson CG, Berggren PO, Efendic S, Meister B.

    Biochem Biophys Res Commun. 2002 Mar 8;291(4):1038-44.PMID: 11866470 [PubMed - indexed for MEDLINE]Related articles

    8.

    Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels.

    Wolf-Goldberg T, Michaelevski I, Sheu L, Gaisano HY, Chikvashvili D, Lotan I.

    Mol Pharmacol. 2006 Sep;70(3):818-28. Epub 2006 Jun 5.PMID: 16754785 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Transgenic mouse overexpressing syntaxin-1A as a diabetes model.

    Lam PP, Leung YM, Sheu L, Ellis J, Tsushima RG, Osborne LR, Gaisano HY.

    Diabetes. 2005 Sep;54(9):2744-54.PMID: 16123365 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Prolactin modulates the association and phosphorylation of SNARE and kinesin/MAP-2 proteins in neonatal pancreatic rat islets.

    Cunha DA, Roma LP, Boschero AC.

    Mol Cell Endocrinol. 2007 Jul 15;273(1-2):32-41. Epub 2007 May 13.PMID: 17573185 [PubMed - indexed for MEDLINE]Related articles

    11.

    The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

    Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

    Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.PMID: 17906960 [PubMed - indexed for MEDLINE]Related articles

    12.

    alpha-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic beta cells and functions in insulin but not gamma-aminobutyric acid secretion.

    Nagamatsu S, Watanabe T, Nakamichi Y, Yamamura C, Tsuzuki K, Matsushima S.

    J Biol Chem. 1999 Mar 19;274(12):8053-60.PMID: 10075705 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex.

    Thurmond DC, Gonelle-Gispert C, Furukawa M, Halban PA, Pessin JE.

    Mol Endocrinol. 2003 Apr;17(4):732-42. Epub 2003 Jan 16.PMID: 12554769 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis.

    Xia F, Gao X, Kwan E, Lam PP, Chan L, Sy K, Sheu L, Wheeler MB, Gaisano HY, Tsushima RG.

    J Biol Chem. 2004 Jun 4;279(23):24685-91. Epub 2004 Apr 8.PMID: 15073181 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Beta-cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and reduced SNARE protein expression.

    Chan CB, MacPhail RM, Sheu L, Wheeler MB, Gaisano HY.

    Diabetes. 1999 May;48(5):997-1005.PMID: 10331403 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.

    Ling C, Del Guerra S, Lupi R, Rönn T, Granhall C, Luthman H, Masiello P, Marchetti P, Groop L, Del Prato S.

    Diabetologia. 2008 Apr;51(4):615-22. Epub 2008 Feb 13.PMID: 18270681 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

    Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL.

    Diabetes. 2005 Nov;54(11):3238-44.PMID: 16249450 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Syntaxin, but not soluble NSF attachment protein (SNAP), biosynthesis by rat pancreatic islets is regulated by glucose in parallel with proinsulin biosynthesis.

    Nagamatsu S, Nakamichi Y, Katahira H.

    Diabetologia. 1997 Dec;40(12):1396-402.PMID: 9447946 [PubMed - indexed for MEDLINE]Related articles

    19.

    Alpha-SNAP functions in insulin exocytosis from mature, but not immature secretory granules in pancreatic beta cells.

    Nakamichi Y, Nagamatsu S.

    Biochem Biophys Res Commun. 1999 Jun 24;260(1):127-32.PMID: 10381355 [PubMed - indexed for MEDLINE]Related articles

    20.

    Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.

    Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O'Connell PJ, Gonzalez FJ, Kahn CR.

    Cell. 2005 Aug 12;122(3):337-49.PMID: 16096055 [PubMed - indexed for MEDLINE]Related articles

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