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Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing.
Kang L, Dunn-Meynell AA, Routh VH, Gaspers LD, Nagata Y, Nishimura T, Eiki J, Zhang BB, Levin BE.
Diabetes. 2006 Feb;55(2):412-20. Erratum in: Diabetes. 2006 Mar;55(3):862. PMID: 16443775 [PubMed - indexed for MEDLINE]Related articlesFree article
Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.
Kang L, Sanders NM, Dunn-Meynell AA, Gaspers LD, Routh VH, Thomas AP, Levin BE.
Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R784-92. Epub 2007 Dec 19.PMID: 18094065 [PubMed - indexed for MEDLINE]Related articles
Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons.
Dunn-Meynell AA, Routh VH, Kang L, Gaspers L, Levin BE.
Diabetes. 2002 Jul;51(7):2056-65.PMID: 12086933 [PubMed - indexed for MEDLINE]Related articlesFree article
Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons.
Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE.
Diabetes. 2004 Mar;53(3):549-59.PMID: 14988237 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus.
Song Z, Routh VH.
Diabetes. 2005 Jan;54(1):15-22.PMID: 15616006 [PubMed - indexed for MEDLINE]Related articlesFree article
Caudal hindbrain lactate infusion alters glucokinase, SUR1, and neuronal substrate fuel transporter gene expression in the dorsal vagal complex, lateral hypothalamic area, and ventromedial nucleus hypothalamus of hypoglycemic male rats.
Vavaiya KV, Briski KP.
Brain Res. 2007 Oct 24;1176:62-70. Epub 2007 Aug 10.PMID: 17889836 [PubMed - indexed for MEDLINE]Related articles
Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing.
Le Foll C, Irani BG, Magnan C, Dunn-Meynell AA, Levin BE.
Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R655-64. Epub 2009 Jun 17.PMID: 19535676 [PubMed - indexed for MEDLINE]Related articles
Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus.
Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH.
Diabetes. 2001 Dec;50(12):2673-81.PMID: 11723049 [PubMed - indexed for MEDLINE]Related articlesFree article
Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding.
Dunn-Meynell AA, Sanders NM, Compton D, Becker TC, Eiki J, Zhang BB, Levin BE.
J Neurosci. 2009 May 27;29(21):7015-22.PMID: 19474328 [PubMed - indexed for MEDLINE]Related articlesFree article
Ventromedial hypothalamic glucokinase is an important mediator of the counterregulatory response to insulin-induced hypoglycemia.
Levin BE, Becker TC, Eiki J, Zhang BB, Dunn-Meynell AA.
Diabetes. 2008 May;57(5):1371-9. Epub 2008 Feb 21.PMID: 18292346 [PubMed - indexed for MEDLINE]Related articlesFree article
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides.
Wang R, Liu X, Hentges ST, Dunn-Meynell AA, Levin BE, Wang W, Routh VH.
Diabetes. 2004 Aug;53(8):1959-65.PMID: 15277373 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of caudal fourth ventricular lactate infusion on hypoglycemia-associated MCT2, GLUT3, GLUT4, GCK, and sulfonylurea receptor-1 gene expression in the ovariectomized female rat LHA and VMH: impact of estradiol.
J Mol Neurosci. 2008 Feb;34(2):121-9. Epub 2007 Dec 15.PMID: 18084728 [PubMed - indexed for MEDLINE]Related articles
Localization of glucokinase gene expression in the rat brain.
Lynch RM, Tompkins LS, Brooks HL, Dunn-Meynell AA, Levin BE.
Diabetes. 2000 May;49(5):693-700.PMID: 10905475 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.
Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.
Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article
Ventromedial nucleus neurons are less sensitive to leptin excitation in rats bred to develop diet-induced obesity.
Irani BG, Le Foll C, Dunn-Meynell AA, Levin BE.
Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R521-7. Epub 2008 Dec 31.PMID: 19118094 [PubMed - indexed for MEDLINE]Related articles
Effects of leptin on rat ventromedial hypothalamic neurons.
Irani BG, Le Foll C, Dunn-Meynell A, Levin BE.
Endocrinology. 2008 Oct;149(10):5146-54. Epub 2008 Jun 12.PMID: 18556346 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.
Canabal DD, Song Z, Potian JG, Beuve A, McArdle JJ, Routh VH.
Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1418-28. Epub 2006 Dec 14.PMID: 17170237 [PubMed - indexed for MEDLINE]Related articles
Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells.
Yang J, Wong RK, Park M, Wu J, Cook JR, York DA, Deng S, Markmann J, Naji A, Wolf BA, Gao Z.
Diabetes. 2006 Jan;55(1):193-201.PMID: 16380493 [PubMed - indexed for MEDLINE]Related articlesFree article
Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose.
Yang XJ, Kow LM, Pfaff DW, Mobbs CV.
Diabetes. 2004 Jan;53(1):67-73.PMID: 14693699 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of glucose and insulin on glucokinase activity in rat hypothalamus.
Sanz C, Roncero I, Vázquez P, Navas MA, Blázquez E.
J Endocrinol. 2007 May;193(2):259-67.PMID: 17470517 [PubMed - indexed for MEDLINE]Related articlesFree article
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