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    Results: 1 to 20 of 218

    1.

    Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1beta and -1alpha mutations.

    Brackenridge A, Pearson ER, Shojaee-Moradie F, Hattersley AT, Russell-Jones D, Umpleby AM.

    Diabetes. 2006 Feb;55(2):405-11.PMID: 16443774 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucose utilization and production in patients with maturity-onset diabetes of the young caused by a mutation of the hepatocyte nuclear factor-1alpha gene.

    Surmely JF, Guenat E, Philippe J, Dussoix P, Schneiter P, Temler E, Vaxillaire M, Froguel P, Jéquier E, Tappy L.

    Diabetes. 1998 Sep;47(9):1459-63.PMID: 9726235 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Contrasting diabetes phenotypes associated with hepatocyte nuclear factor-1alpha and -1beta mutations.

    Pearson ER, Badman MK, Lockwood CR, Clark PM, Ellard S, Bingham C, Hattersley AT.

    Diabetes Care. 2004 May;27(5):1102-7.PMID: 15111528 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.

    Pearson ER, Velho G, Clark P, Stride A, Shepherd M, Frayling TM, Bulman MP, Ellard S, Froguel P, Hattersley AT.

    Diabetes. 2001 Feb;50 Suppl 1:S101-7.PMID: 11272165 [PubMed - indexed for MEDLINE]Related articles

    5.

    Counterregulatory responses to hypoglycemia in patients with maturity-onset diabetes of the young caused by HNF-1alpha gene mutations (MODY3).

    Guenat E, Seematter G, Philippe J, Temler E, Jéquier E, Tappy L.

    Eur J Endocrinol. 2001 Jan;144(1):45-9.PMID: 11174836 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.

    Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I.

    Gene Expr Patterns. 2008 Jan;8(2):96-106. Epub 2007 Oct 9.PMID: 17996499 [PubMed - indexed for MEDLINE]Related articles

    7.

    Regulation of human insulin, IGF-I, and multidrug resistance protein 2 promoter activity by hepatocyte nuclear factor (HNF)-1beta and HNF-1alpha and the abnormality of HNF-1beta mutants.

    Kitanaka S, Sato U, Igarashi T.

    J Endocrinol. 2007 Jan;192(1):141-7.PMID: 17210751 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Beta-cell dysfunction, insulin sensitivity, and glycosuria precede diabetes in hepatocyte nuclear factor-1alpha mutation carriers.

    Stride A, Ellard S, Clark P, Shakespeare L, Salzmann M, Shepherd M, Hattersley AT.

    Diabetes Care. 2005 Jul;28(7):1751-6.PMID: 15983330 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.

    Okita K, Yang Q, Yamagata K, Hangenfeldt KA, Miyagawa J, Kajimoto Y, Nakajima H, Namba M, Wollheim CB, Hanafusa T, Matsuzawa Y.

    Biochem Biophys Res Commun. 1999 Sep 24;263(2):566-9.PMID: 10491332 [PubMed - indexed for MEDLINE]Related articles

    10.

    Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.

    Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, Polonsky KS.

    J Clin Invest. 1998 May 15;101(10):2215-22.PMID: 9593777 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.

    Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M.

    Diabetes. 2003 Dec;52(12):2989-95.PMID: 14633861 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1alpha (maturity-onset diabetes of the young-3) mutations.

    Vaxillaire M, Pueyo ME, Clément K, Fiet J, Timsit J, Philippe J, Robert JJ, Tappy L, Froguel P, Velho G.

    Eur J Endocrinol. 1999 Dec;141(6):609-18.PMID: 10601964 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers.

    Sagen JV, Pearson ER, Johansen A, Spyer G, Søvik O, Pedersen O, Njølstad PR, Hattersley AT, Hansen T.

    Diabet Med. 2005 Apr;22(4):406-9.PMID: 15787664 [PubMed - indexed for MEDLINE]Related articles

    15.

    Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.

    Holmkvist J, Almgren P, Lyssenko V, Lindgren CM, Eriksson KF, Isomaa B, Tuomi T, Nilsson P, Groop L.

    Diabetes. 2008 Jun;57(6):1738-44. Epub 2008 Mar 10.PMID: 18332101 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).

    Boileau P, Wolfrum C, Shih DQ, Yang TA, Wolkoff AW, Stoffel M.

    Diabetes. 2002 Dec;51 Suppl 3:S343-8.PMID: 12475773 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells.

    Gu N, Suzuki N, Takeda J, Adachi T, Tsujimoto G, Aoki N, Ishihara A, Tsuda K, Yasuda K.

    Biochem Biophys Res Commun. 2004 Dec 3;325(1):308-13.PMID: 15522234 [PubMed - indexed for MEDLINE]Related articles

    18.

    The generalized aminoaciduria seen in patients with hepatocyte nuclear factor-1alpha mutations is a feature of all patients with diabetes and is associated with glucosuria.

    Bingham C, Ellard S, Nicholls AJ, Pennock CA, Allen J, James AJ, Satchell SC, Salzmann MB, Hattersley AT.

    Diabetes. 2001 Sep;50(9):2047-52.PMID: 11522670 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A low renal threshold for glucose in diabetic patients with a mutation in the hepatocyte nuclear factor-1alpha (HNF-1alpha) gene.

    Menzel R, Kaisaki PJ, Rjasanowski I, Heinke P, Kerner W, Menzel S.

    Diabet Med. 1998 Oct;15(10):816-20.PMID: 9796880 [PubMed - indexed for MEDLINE]Related articles

    20.

    A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.

    Urhammer SA, Fridberg M, Hansen T, Rasmussen SK, Møller AM, Clausen JO, Pedersen O.

    Diabetes. 1997 May;46(5):912-6.PMID: 9133564 [PubMed - indexed for MEDLINE]Related articles

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