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    Results: 1 to 20 of 380

    1.

    Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes.

    Chu KY, Lau T, Carlsson PO, Leung PS.

    Diabetes. 2006 Feb;55(2):367-74.PMID: 16443769 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Angiotensin II Type 1 receptor antagonism mediates uncoupling protein 2-driven oxidative stress and ameliorates pancreatic islet beta-cell function in young Type 2 diabetic mice.

    Chu KY, Leung PS.

    Antioxid Redox Signal. 2007 Jul;9(7):869-78.PMID: 17508912 [PubMed - indexed for MEDLINE]Related articles

    3.

    Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.

    Lau T, Carlsson PO, Leung PS.

    Diabetologia. 2004 Feb;47(2):240-8. Epub 2004 Jan 13.PMID: 14722647 [PubMed - indexed for MEDLINE]Related articles

    4.

    Angiotensin II type 1 receptor inhibition markedly improves the blood perfusion, oxygen tension and first phase of glucose-stimulated insulin secretion in revascularised syngeneic mouse islet grafts.

    Kampf C, Lau T, Olsson R, Leung PS, Carlsson PO.

    Diabetologia. 2005 Jun;48(6):1159-67. Epub 2005 May 5.PMID: 15877216 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effects of hyperglycemia on angiotensin II receptor type 1 expression and insulin secretion in an INS-1E pancreatic beta-cell line.

    Leung KK, Leung PS.

    JOP. 2008 May 8;9(3):290-9.PMID: 18469441 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    [Effects of angiotensin II type 1 receptor blocker on islet of diabetic db/db mice]

    Shao JQ, Iwashita N, Du H, Wang YY, Zhao M, Wang J, Watada H, Kawamori R.

    Zhonghua Nei Ke Za Zhi. 2007 Apr;46(4):306-10. Chinese. PMID: 17637271 [PubMed - indexed for MEDLINE]Related articles

    7.

    Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes.

    Cheng Q, Law PK, de Gasparo M, Leung PS.

    J Pharmacol Exp Ther. 2008 Dec;327(3):683-91. Epub 2008 Sep 11.PMID: 18787107 [PubMed - indexed for MEDLINE]Related articles

    8.

    Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.

    Chipitsyna G, Gong Q, Gray CF, Haroon Y, Kamer E, Arafat HA.

    Endocrinology. 2007 May;148(5):2198-208. Epub 2007 Feb 15.PMID: 17303665 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice.

    Shao J, Iwashita N, Ikeda F, Ogihara T, Uchida T, Shimizu T, Uchino H, Hirose T, Kawamori R, Watada H.

    Biochem Biophys Res Commun. 2006 Jun 16;344(4):1224-33. Epub 2006 Apr 21.PMID: 16650382 [PubMed - indexed for MEDLINE]Related articles

    10.

    Angiotensin II receptor blocker provides pancreatic beta-cell protection independent of blood pressure lowering in diabetic db/db mice.

    Shao JQ, Iwashita N, Du H, Wang YT, Wang YY, Zhao M, Wang J, Watada H, Kawamori R.

    Acta Pharmacol Sin. 2007 Feb;28(2):246-57. Retraction in: Shao JQ, Iwashita N, Du H, Wang YT, Wang YY, Zhao M, Wang J, Watada H, Kawamori R. Acta Pharmacol Sin. 2007 Oct;28(10):1705. PMID: 17241528 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R.

    Wang XP, Zhang R, Wu K, Wu L, Dong Y.

    Pancreas. 2004 Nov;29(4):264-70.PMID: 15502641 [PubMed - indexed for MEDLINE]Related articles

    12.

    Angiotensin type-1 receptor blockade with losartan increases insulin sensitivity and improves glucose homeostasis in subjects with type 2 diabetes and nephropathy.

    Jin HM, Pan Y.

    Nephrol Dial Transplant. 2007 Jul;22(7):1943-9. Epub 2007 Feb 17.PMID: 17308317 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the Ljungan virus.

    Blixt M, Niklasson B, Sandler S.

    Gen Comp Endocrinol. 2007 Oct-Dec;154(1-3):41-7. Epub 2007 Jul 4.PMID: 17686482 [PubMed - indexed for MEDLINE]Related articles

    14.

    Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

    Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

    Diabetes. 2006 Sep;55(9):2470-8.PMID: 16936195 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Cardiovascular and autonomic phenotype of db/db diabetic mice.

    Senador D, Kanakamedala K, Irigoyen MC, Morris M, Elased KM.

    Exp Physiol. 2009 Jun;94(6):648-58. Epub 2009 Feb 13.PMID: 19218356 [PubMed - indexed for MEDLINE]Related articles

    16.

    Bromocriptine/SKF38393 ameliorates islet dysfunction in the diabetic (db/db) mouse.

    Liang Y, Jetton TL, Lubkin M, Meier AH, Cincotta AH.

    Cell Mol Life Sci. 1998 Jul;54(7):703-11.PMID: 9711236 [PubMed - indexed for MEDLINE]Related articles

    17.

    Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade.

    Xu ZG, Lanting L, Vaziri ND, Li Z, Sepassi L, Rodriguez-Iturbe B, Natarajan R.

    Circulation. 2005 Apr 19;111(15):1962-9.PMID: 15837950 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia.

    Garris DR, Garris BL.

    Cell Tissue Res. 2005 Feb;319(2):231-42. Epub 2004 Nov 20.PMID: 15654653 [PubMed - indexed for MEDLINE]Related articles

    19.

    Novel glucagon-like peptide-1 (GLP-1) analog (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta-cell function after 3-week daily administration in obese diabetic (ob/ob) mice.

    Green BD, Lavery KS, Irwin N, O'harte FP, Harriott P, Greer B, Bailey CJ, Flatt PR.

    J Pharmacol Exp Ther. 2006 Aug;318(2):914-21. Epub 2006 Apr 28.PMID: 16648370 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Short-term administration of an angiotensin-receptor antagonist in patients with impaired fasting glucose improves insulin sensitivity and increases free IGF-I.

    Zandbergen AA, Lamberts SW, Janssen JA, Bootsma AH.

    Eur J Endocrinol. 2006 Aug;155(2):293-6.PMID: 16868143 [PubMed - indexed for MEDLINE]Related articlesFree article

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