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    Results: 1 to 20 of 288

    1.

    Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity.

    Fatrai S, Elghazi L, Balcazar N, Cras-Méneur C, Krits I, Kiyokawa H, Bernal-Mizrachi E.

    Diabetes. 2006 Feb;55(2):318-25.PMID: 16443763 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Beta-cell growth: an unusual paradigm of organogenesis that is cyclin D2/Cdk4 dependent.

    Kushner JA.

    Cell Cycle. 2006 Feb;5(3):234-7. Epub 2006 Feb 9.PMID: 16410729 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Overexpression of Reg3alpha increases cell growth and the levels of cyclin D1 and CDK4 in insulinoma cells.

    Cui W, De Jesus K, Zhao H, Takasawa S, Shi B, Srikant CB, Liu JL.

    Growth Factors. 2009 Jun;27(3):195-202.PMID: 19343564 [PubMed - indexed for MEDLINE]Related articles

    4.

    Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.

    Paternot S, Dumont JE, Roger PP.

    Mol Endocrinol. 2006 Dec;20(12):3279-92. Epub 2006 Aug 17.PMID: 16916940 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability.

    Balcazar N, Sathyamurthy A, Elghazi L, Gould A, Weiss A, Shiojima I, Walsh K, Bernal-Mizrachi E.

    J Biol Chem. 2009 Mar 20;284(12):7832-42. Epub 2009 Jan 14.PMID: 19144649 [PubMed - indexed for MEDLINE]Related articles

    6.

    Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice.

    Chiu H, Gardner CR, Dambach DM, Durham SK, Brittingham JA, Laskin JD, Laskin DL.

    Toxicol Appl Pharmacol. 2003 Dec 1;193(2):218-27.PMID: 14644624 [PubMed - indexed for MEDLINE]Related articles

    7.

    AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival.

    Li Y, Dowbenko D, Lasky LA.

    J Biol Chem. 2002 Mar 29;277(13):11352-61. Epub 2001 Dec 27.PMID: 11756412 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model.

    Yu X, Luo Y, Zhou Y, Zhang Q, Wang J, Wei N, Mi M, Zhu J, Wang B, Chang H, Tang Y.

    Int J Oncol. 2008 Sep;33(3):555-63.PMID: 18695886 [PubMed - indexed for MEDLINE]Related articles

    9.

    Cyclin D2 compensates for the loss of cyclin D1 in estrogen-induced mouse uterine epithelial cell proliferation.

    Chen B, Pollard JW.

    Mol Endocrinol. 2003 Jul;17(7):1368-81. Epub 2003 Mar 20.PMID: 12649329 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Involvement of cyclin D1/CDK4 and pRb mediated by PI3K/AKT pathway activation in Pb2+ -induced neuronal death in cultured hippocampal neurons.

    Li C, Xing T, Tang M, Yong W, Yan D, Deng H, Wang H, Wang M, Chen J, Ruan D.

    Toxicol Appl Pharmacol. 2008 Jun 15;229(3):351-61. Epub 2008 Feb 16.PMID: 18353414 [PubMed - indexed for MEDLINE]Related articles

    11.

    Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth.

    Kushner JA, Ciemerych MA, Sicinska E, Wartschow LM, Teta M, Long SY, Sicinski P, White MF.

    Mol Cell Biol. 2005 May;25(9):3752-62.PMID: 15831479 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma.

    Ely S, Di Liberto M, Niesvizky R, Baughn LB, Cho HJ, Hatada EN, Knowles DM, Lane J, Chen-Kiang S.

    Cancer Res. 2005 Dec 15;65(24):11345-53.PMID: 16357141 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1.

    Yang W, Zhang Y, Li Y, Wu Z, Zhu D.

    J Biol Chem. 2007 Feb 9;282(6):3799-808. Epub 2006 Nov 27.PMID: 17130121 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

    Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, Petersen JS, Nielsen JH, Møldrup A.

    J Endocrinol. 2006 Mar;188(3):481-92.PMID: 16522728 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Ectopic expression of cyclin D3 corrects differentiation of DM1 myoblasts through activation of RNA CUG-binding protein, CUGBP1.

    Salisbury E, Sakai K, Schoser B, Huichalaf C, Schneider-Gold C, Nguyen H, Wang GL, Albrecht JH, Timchenko LT.

    Exp Cell Res. 2008 Jul 1;314(11-12):2266-78. Epub 2008 May 10.PMID: 18570922 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors.

    Evans-Anderson HJ, Alfieri CM, Yutzey KE.

    Circ Res. 2008 Mar 28;102(6):686-94. Epub 2008 Jan 24.PMID: 18218983 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression.

    Kim DI, Lee SJ, Lee SB, Park K, Kim WJ, Moon SK.

    Carcinogenesis. 2008 Sep;29(9):1701-9. Epub 2008 Feb 22.PMID: 18296682 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.

    Lee SH, Lee MY, Han HJ.

    Cell Prolif. 2008 Apr;41(2):230-47.PMID: 18336469 [PubMed - indexed for MEDLINE]Related articles

    19.

    Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest.

    Mullany LK, Nelsen CJ, Hanse EA, Goggin MM, Anttila CK, Peterson M, Bitterman PB, Raghavan A, Crary GS, Albrecht JH.

    J Biol Chem. 2007 Jul 20;282(29):21244-52. Epub 2007 May 21.PMID: 17517888 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia.

    Smartt HJ, Guilmeau S, Nasser SV, Nicholas C, Bancroft L, Simpson SA, Yeh N, Yang W, Mariadason JM, Koff A, Augenlicht LH.

    Gastroenterology. 2007 Jul;133(1):232-43. Epub 2007 Apr 25.PMID: 17631145 [PubMed - indexed for MEDLINE]Related articles

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