PubMed

A2e mediated phototoxic effects of endoilluminators.

Yanagi Y, Inoue Y, Jang WD, Kadonosono K.

Br J Ophthalmol. 2006 Feb;90(2):229-32.PMID: 16424539 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the safety of xenon/bandpass light in vitrectomy using the A2E-laden RPE model.

Yanagi Y, Iriyama A, Jang WD, Kadonosono K.

Graefes Arch Clin Exp Ophthalmol. 2007 May;245(5):677-81. Epub 2006 Oct 17.PMID: 17043808 [PubMed - indexed for MEDLINE]Related articles

[Retinal phototoxicity from endoilluminators for vitrectomy]

Yanagi Y.

Nippon Ganka Gakkai Zasshi. 2008 Nov;112(11):975-83. Review. Japanese. PMID: 19069380 [PubMed - indexed for MEDLINE]Related articles

Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE.

Sparrow JR, Zhou J, Ben-Shabat S, Vollmer H, Itagaki Y, Nakanishi K.

Invest Ophthalmol Vis Sci. 2002 Apr;43(4):1222-7.PMID: 11923269 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of yellow intraocular lenses on light-induced upregulation of vascular endothelial growth factor.

Yanagi Y, Inoue Y, Iriyama A, Jang WD.

J Cataract Refract Surg. 2006 Sep;32(9):1540-4.PMID: 16931269 [PubMed - indexed for MEDLINE]Related articles

DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination.

Sparrow JR, Zhou J, Cai B.

Invest Ophthalmol Vis Sci. 2003 May;44(5):2245-51.PMID: 12714667 [PubMed - indexed for MEDLINE]Related articlesFree article

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation.

Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP, Jockusch S, Itagaki Y, Nakanishi K.

J Biol Chem. 2003 May 16;278(20):18207-13. Epub 2003 Mar 19.PMID: 12646558 [PubMed - indexed for MEDLINE]Related articlesFree article

Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro.

Sparrow JR, Miller AS, Zhou J.

J Cataract Refract Surg. 2004 Apr;30(4):873-8.PMID: 15093654 [PubMed - indexed for MEDLINE]Related articles

Retinal irradiance from vitrectomy endoilluminators.

Meyers SM, Bonner RF.

Am J Ophthalmol. 1982 Jul;94(1):26-9.PMID: 7091278 [PubMed - indexed for MEDLINE]Related articles

The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

Sparrow JR, Nakanishi K, Parish CA.

Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1981-9.PMID: 10845625 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light.

Westlund BS, Cai B, Zhou J, Sparrow JR.

Apoptosis. 2009 Jan;14(1):31-41.PMID: 19052872 [PubMed - indexed for MEDLINE]Related articles

The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells.

Roberts JE, Kukielczak BM, Hu DN, Miller DS, Bilski P, Sik RH, Motten AG, Chignell CF.

Photochem Photobiol. 2002 Feb;75(2):184-90.PMID: 11883606 [PubMed - indexed for MEDLINE]Related articles

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells.

Lakkaraju A, Finnemann SC, Rodriguez-Boulan E.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11026-31. Epub 2007 Jun 19. Erratum in: Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):11032. PMID: 17578916 [PubMed - indexed for MEDLINE]Related articlesFree article

Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells.

Jang YP, Zhou J, Nakanishi K, Sparrow JR.

Photochem Photobiol. 2005 May-Jun;81(3):529-36.PMID: 15745429 [PubMed - indexed for MEDLINE]Related articlesFree article

A2E, a byproduct of the visual cycle.

Sparrow JR, Fishkin N, Zhou J, Cai B, Jang YP, Krane S, Itagaki Y, Nakanishi K.

Vision Res. 2003 Dec;43(28):2983-90. Review.PMID: 14611934 [PubMed - indexed for MEDLINE]Related articles

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium.

Finnemann SC, Leung LW, Rodriguez-Boulan E.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3842-7.PMID: 11904436 [PubMed - indexed for MEDLINE]Related articlesFree article

The proteasome: a target of oxidative damage in cultured human retina pigment epithelial cells.

Zhang X, Zhou J, Fernandes AF, Sparrow JR, Pereira P, Taylor A, Shang F.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3622-30. Epub 2008 Apr 11.PMID: 18408178 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin.

Jang YP, Matsuda H, Itagaki Y, Nakanishi K, Sparrow JR.

J Biol Chem. 2005 Dec 2;280(48):39732-9. Epub 2005 Sep 26.PMID: 16186115 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylglycerol potently protects human retinal pigment epithelial cells against apoptosis induced by A2E, a compound suspected to cause age-related macula degeneration.

Shaban H, Borrás C, Viña J, Richter C.

Exp Eye Res. 2002 Jul;75(1):99-108.PMID: 12123641 [PubMed - indexed for MEDLINE]Related articles

Comparison of the in vitro toxicity of indocyanine green to that of trypan blue in human retinal pigment epithelium cell cultures.

Gale JS, Proulx AA, Gonder JR, Mao AJ, Hutnik CM.

Am J Ophthalmol. 2004 Jul;138(1):64-9.PMID: 15234283 [PubMed - indexed for MEDLINE]Related articles