PubMed

Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells.

Yang J, Wong RK, Park M, Wu J, Cook JR, York DA, Deng S, Markmann J, Naji A, Wolf BA, Gao Z.

Diabetes. 2006 Jan;55(1):193-201.PMID: 16380493 [PubMed - indexed for MEDLINE]Related articlesFree article

Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells.

Yang J, Wong RK, Wang X, Moibi J, Hessner MJ, Greene S, Wu J, Sukumvanich S, Wolf BA, Gao Z.

J Biol Chem. 2004 Dec 24;279(52):53915-23. Epub 2004 Oct 14.PMID: 15489222 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential sensitivity to beta-cell secretagogues in cultured rat pancreatic islets exposed to human interleukin-1 beta.

Eizirik DL, Sandler S, Hallberg A, Bendtzen K, Sener A, Malaisse WJ.

Endocrinology. 1989 Aug;125(2):752-9.PMID: 2666106 [PubMed - indexed for MEDLINE]Related articles

Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells.

Morgan D, Rebelato E, Abdulkader F, Graciano MF, Oliveira-Emilio HR, Hirata AE, Rocha MS, Bordin S, Curi R, Carpinelli AR.

Endocrinology. 2009 May;150(5):2197-201. Epub 2009 Jan 15.PMID: 19147679 [PubMed - indexed for MEDLINE]Related articles

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial-encoded gene regulation in rat pancreatic islets.

Lee B, Srinivasan M, Aalinkeel R, Patel MS, Laychock SG.

Metabolism. 2001 Feb;50(2):200-6.PMID: 11229430 [PubMed - indexed for MEDLINE]Related articles

Glucose regulation of glutaminolysis and its role in insulin secretion.

Gao ZY, Li G, Najafi H, Wolf BA, Matschinsky FM.

Diabetes. 1999 Aug;48(8):1535-42.PMID: 10426370 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucokinase in pancreatic islets by prolactin: a mechanism for increasing glucose-stimulated insulin secretion during pregnancy.

Weinhaus AJ, Stout LE, Bhagroo NV, Brelje TC, Sorenson RL.

J Endocrinol. 2007 Jun;193(3):367-81.PMID: 17535875 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase, hexokinase, glucose transporter 2, and glucose metabolism in islets during pregnancy and prolactin-treated islets in vitro: mechanisms for long term up-regulation of islets.

Weinhaus AJ, Stout LE, Sorenson RL.

Endocrinology. 1996 May;137(5):1640-9.PMID: 8612496 [PubMed - indexed for MEDLINE]Related articles

Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm.

Matschinsky FM.

Diabetes. 1996 Feb;45(2):223-41. Review.PMID: 8549869 [PubMed - indexed for MEDLINE]Related articles

Immaturity of glucose-induced insulin secretion in fetal rat islets is due to low glucokinase activity.

Taniguchi S, Tanigawa K, Miwa I.

Horm Metab Res. 2000 Mar;32(3):97-102.PMID: 10786927 [PubMed - indexed for MEDLINE]Related articles

Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM.

Diabetes. 2003 Apr;52(4):965-73.PMID: 12663468 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

Biochem J. 2008 Apr 1;411(1):41-51.PMID: 18039179 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

Pertusa JA, Nesher R, Kaiser N, Cerasi E, Henquin JC, Jonas JC.

Diabetes. 2002 Aug;51(8):2552-60.PMID: 12145170 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion.

Macdonald MJ, Hasan NM, Longacre MJ.

Biochim Biophys Acta. 2008 Jul-Aug;1780(7-8):966-72. Epub 2008 Apr 4.PMID: 18439432 [PubMed - indexed for MEDLINE]Related articlesFree article

Biotin regulation of pancreatic glucokinase and insulin in primary cultured rat islets and in biotin-deficient rats.

Romero-Navarro G, Cabrera-Valladares G, German MS, Matschinsky FM, Velazquez A, Wang J, Fernandez-Mejia C.

Endocrinology. 1999 Oct;140(10):4595-600.PMID: 10499515 [PubMed - indexed for MEDLINE]Related articlesFree article

Streptozotocin (STZ) mediates acute upregulation of serum and pancreatic osteopontin (OPN): a novel islet-protective effect of OPN through inhibition of STZ-induced nitric oxide production.

Katakam AK, Chipitsyna G, Gong Q, Vancha AR, Gabbeta J, Arafat HA.

J Endocrinol. 2005 Nov;187(2):237-47.PMID: 16293771 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.

Takehiro M, Fujimoto S, Shimodahira M, Shimono D, Mukai E, Nabe K, Radu RG, Kominato R, Aramaki Y, Seino Y, Yamada Y.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E372-80. Epub 2004 Oct 12.PMID: 15479955 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates leucine-induced insulin release and the expression of the branched chain ketoacid dehydrogenase E1 alpha subunit gene in pancreatic islets.

MacDonald MJ, McKenzie DI, Kaysen JH, Walker TM, Moran SM, Fahien LA, Towle HC.

J Biol Chem. 1991 Jan 15;266(2):1335-40.PMID: 1985951 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose.

Heart E, Yaney GC, Corkey RF, Schultz V, Luc E, Liu L, Deeney JT, Shirihai O, Tornheim K, Smith PJ, Corkey BE.

Biochem J. 2007 Apr 1;403(1):197-205.PMID: 17181533 [PubMed - indexed for MEDLINE]Related articlesFree article