PubMed

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people.

Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PI, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L.

Diabetes. 2006 Jan;55(1):128-35.PMID: 16380485 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels.

Gu HF, Efendic S, Nordman S, Ostenson CG, Brismar K, Brookes AJ, Prince JA.

Diabetes. 2004 Aug;53(8):2137-42.PMID: 15277398 [PubMed - indexed for MEDLINE]Related articlesFree article

Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.

Groves CJ, Wiltshire S, Smedley D, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, O'Rahilly S, Menzel S, Hattersley AT, McCarthy MI.

Diabetes. 2003 May;52(5):1300-5.PMID: 12716770 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of polymorphisms in the insulin-degrading enzyme gene with type 2 diabetes in the Korean population.

Kwak SH, Cho YM, Moon MK, Kim JH, Park BL, Cheong HS, Shin HD, Jang HC, Kim SY, Lee HK, Park KS.

Diabetes Res Clin Pract. 2008 Feb;79(2):284-90. Epub 2007 Oct 25.PMID: 17913278 [PubMed - indexed for MEDLINE]Related articles

Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.

Abraham R, Myers A, Wavrant-DeVrieze F, Hamshere ML, Thomas HV, Marshall H, Compton D, Spurlock G, Turic D, Hoogendoorn B, Kwon JM, Petersen RC, Tangalos E, Norton J, Morris JC, Bullock R, Liolitsa D, Lovestone S, Hardy J, Goate A, O'Donovan M, Williams J, Owen MJ, Jones L.

Hum Genet. 2001 Dec;109(6):646-52. Epub 2001 Nov 1.PMID: 11810277 [PubMed - indexed for MEDLINE]Related articles

Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.

Elbein SC, Chu W, Ren Q, Hemphill C, Schay J, Cox NJ, Hanis CL, Hasstedt SJ.

J Clin Endocrinol Metab. 2002 Feb;87(2):650-4.PMID: 11836299 [PubMed - indexed for MEDLINE]Related articlesFree article

Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.

Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, Gibson AM, McKeith IG, Perry RH, Morris CM, Thal L, Morris JC, O'Donovan MC, Lovestone S, Grupe A, Hardy J, Owen MJ, Williams J, Goate A.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5;136B(1):62-8.PMID: 15858813 [PubMed - indexed for MEDLINE]Related articles

Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people.

Florez JC, Agapakis CM, Burtt NP, Sun M, Almgren P, Råstam L, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Groop L, Altshuler D.

Diabetes. 2005 Jun;54(6):1884-91.PMID: 15919813 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

Karamohamed S, Demissie S, Volcjak J, Liu C, Heard-Costa N, Liu J, Shoemaker CM, Panhuysen CI, Meigs JB, Wilson P, Atwood LD, Cupples LA, Herbert A; NHLBI Framingham Heart Study.

Diabetes. 2003 Jun;52(6):1562-7.PMID: 12765971 [PubMed - indexed for MEDLINE]Related articlesFree article

AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.

Andersen G, Burgdorf KS, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetes. 2008 May;57(5):1427-32. Epub 2008 Mar 3.PMID: 18316360 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in a haplotype block spanning IDE influences Alzheimer disease.

Prince JA, Feuk L, Gu HF, Johansson B, Gatz M, Blennow K, Brookes AJ.

Hum Mutat. 2003 Nov;22(5):363-71.PMID: 14517947 [PubMed - indexed for MEDLINE]Related articles

Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish.

Sabra MM, Damcott C, Fu M, Ott S, O'Connell JR, Mitchell BD, Shuldiner AR.

Mol Genet Metab. 2005 Jun;85(2):133-9.PMID: 15896658 [PubMed - indexed for MEDLINE]Related articles

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.

Kovacs P, Geyer M, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M.

Diabetes. 2007 Dec;56(12):3095-100. Epub 2007 Aug 29.PMID: 17728376 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of the GLUT10 glucose transporter (SLC2A10) polymorphisms in Caucasian American type 2 diabetes.

Bento JL, Bowden DW, Mychaleckyj JC, Hirakawa S, Rich SS, Freedman BI, Segade F.

BMC Med Genet. 2005 Dec 7;6:42.PMID: 16336637 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease.

Feuk L, McCarthy S, Andersson B, Prince JA, Brookes AJ.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5;136B(1):69-71.PMID: 15858821 [PubMed - indexed for MEDLINE]Related articles

Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study).

Holzapfel C, Klopp N, Grallert H, Huth C, Gieger C, Meisinger C, Strassburger K, Giani G, Wichmann HE, Laumen H, Hauner H, Herder C, Rathmann W, Illig T.

Eur J Endocrinol. 2007 Sep;157(3):R1-5.PMID: 17766704 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.

Cheyssac C, Lecoeur C, Dechaume A, Bibi A, Charpentier G, Balkau B, Marre M, Froguel P, Gibson F, Vaxillaire M.

BMC Med Genet. 2006 May 5;7:44.PMID: 16677372 [PubMed - indexed for MEDLINE]Related articlesFree article

The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.

Ng MC, Miyake K, So WY, Poon EW, Lam VK, Li JK, Cox NJ, Bell GI, Chan JC.

Diabetologia. 2005 Oct;48(10):2018-24. Epub 2005 Aug 26.PMID: 16132950 [PubMed - indexed for MEDLINE]Related articles

Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis.

Das SK, Sharma NK, Chu WS, Wang H, Elbein SC.

BMC Med Genet. 2008 Mar 17;9:16.PMID: 18366646 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease.

Ertekin-Taner N, Allen M, Fadale D, Scanlin L, Younkin L, Petersen RC, Graff-Radford N, Younkin SG.

Hum Mutat. 2004 Apr;23(4):334-42.PMID: 15024728 [PubMed - indexed for MEDLINE]Related articles