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    Results: 1 to 20 of 324

    1.

    Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells.

    Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T, Araki E.

    Diabetes. 2006 Jan;55(1):120-7.PMID: 16380484 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis.

    Fujisawa K, Nishikawa T, Kukidome D, Imoto K, Yamashiro T, Motoshima H, Matsumura T, Araki E.

    Biochem Biophys Res Commun. 2009 Jan 30;379(1):43-8. Epub 2008 Dec 11.PMID: 19084501 [PubMed - indexed for MEDLINE]Related articles

    3.

    Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.

    Hattori Y, Suzuki K, Hattori S, Kasai K.

    Hypertension. 2006 Jun;47(6):1183-8. Epub 2006 Apr 24.PMID: 16636195 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of AMP-activated protein kinase in mechanism of metformin action.

    Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE.

    J Clin Invest. 2001 Oct;108(8):1167-74.PMID: 11602624 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species.

    Zou MH, Kirkpatrick SS, Davis BJ, Nelson JS, Wiles WG 4th, Schlattner U, Neumann D, Brownlee M, Freeman MB, Goldman MH.

    J Biol Chem. 2004 Oct 15;279(42):43940-51. Epub 2004 Jul 19.PMID: 15265871 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.

    Fu X, Wan S, Lyu YL, Liu LF, Qi H.

    PLoS One. 2008 Apr 23;3(4):e2009.PMID: 18431490 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.

    Ouedraogo R, Wu X, Xu SQ, Fuchsel L, Motoshima H, Mahadev K, Hough K, Scalia R, Goldstein BJ.

    Diabetes. 2006 Jun;55(6):1840-6.PMID: 16731851 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase.

    Huypens P, Quartier E, Pipeleers D, Van de Casteele M.

    Eur J Pharmacol. 2005 Aug 22;518(2-3):90-5.PMID: 16039647 [PubMed - indexed for MEDLINE]Related articles

    9.

    Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.

    Cai Y, Martens GA, Hinke SA, Heimberg H, Pipeleers D, Van de Casteele M.

    Free Radic Biol Med. 2007 Jan 1;42(1):64-78. Epub 2006 Sep 27.PMID: 17157194 [PubMed - indexed for MEDLINE]Related articles

    10.

    Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

    Sakamoto K, Göransson O, Hardie DG, Alessi DR.

    Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.PMID: 15068958 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The effect of AMP-activated kinase activation on gonadotrophin-releasing hormone secretion in GT1-7 cells and its potential role in hypothalamic regulation of the oestrous cyclicity in rats.

    Coyral-Castel S, Tosca L, Ferreira G, Jeanpierre E, Rame C, Lomet D, Caraty A, Monget P, Chabrolle C, Dupont J.

    J Neuroendocrinol. 2008 Mar;20(3):335-46. Epub 2008 Jan 11.PMID: 18194429 [PubMed - indexed for MEDLINE]Related articles

    12.

    AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.

    Zang Y, Yu LF, Pang T, Fang LP, Feng X, Wen TQ, Nan FJ, Feng LY, Li J.

    J Biol Chem. 2008 Mar 7;283(10):6201-8. Epub 2007 Dec 12.PMID: 18077446 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.

    Xie Z, Dong Y, Scholz R, Neumann D, Zou MH.

    Circulation. 2008 Feb 19;117(7):952-62. Epub 2008 Feb 4.PMID: 18250273 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

    Davis BJ, Xie Z, Viollet B, Zou MH.

    Diabetes. 2006 Feb;55(2):496-505.PMID: 16443786 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase.

    Kuo CL, Ho FM, Chang MY, Prakash E, Lin WW.

    J Cell Biochem. 2008 Feb 15;103(3):931-40.PMID: 17615555 [PubMed - indexed for MEDLINE]Related articles

    16.

    PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.

    Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM, Hood DA.

    Am J Physiol Cell Physiol. 2003 Jun;284(6):C1669-77.PMID: 12734114 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells.

    Irrcher I, Ljubicic V, Hood DA.

    Am J Physiol Cell Physiol. 2009 Jan;296(1):C116-23. Epub 2008 Nov 12.PMID: 19005163 [PubMed - indexed for MEDLINE]Related articles

    18.

    Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes.

    Xie Z, Zhang J, Wu J, Viollet B, Zou MH.

    Diabetes. 2008 Dec;57(12):3222-30. Epub 2008 Oct 3.PMID: 18835932 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells.

    Morrow VA, Foufelle F, Connell JM, Petrie JR, Gould GW, Salt IP.

    J Biol Chem. 2003 Aug 22;278(34):31629-39. Epub 2003 Jun 4.PMID: 12791703 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

    Jørgensen SB, Wojtaszewski JF, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA, Pilegaard H.

    FASEB J. 2005 Jul;19(9):1146-8. Epub 2005 May 5.PMID: 15878932 [PubMed - indexed for MEDLINE]Related articlesFree article

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