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Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse.
Nanji SA, Hancock WW, Luo B, Schur CD, Pawlick RL, Zhu LF, Anderson CC, Shapiro AM.
Diabetes. 2006 Jan;55(1):27-33.PMID: 16380473 [PubMed - indexed for MEDLINE]Related articlesFree article
Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice.
Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH.
Clin Immunol. 2008 Feb;126(2):140-7. Epub 2007 Sep 24.PMID: 17889619 [PubMed - indexed for MEDLINE]Related articles
Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.
Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Schur CD, Pawlick RL, Wang L, Coyle AJ, Larsen CP, Shapiro AM.
Am J Transplant. 2004 Apr;4(4):526-36.PMID: 15023144 [PubMed - indexed for MEDLINE]Related articles
Islet allograft rejection in nonobese diabetic mice involves the common gamma-chain and CD28/CD154-dependent and -independent mechanisms.
Demirci G, Strom TB, Li XC.
J Immunol. 2003 Oct 1;171(7):3878-85.PMID: 14500690 [PubMed - indexed for MEDLINE]Related articlesFree article
Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
Mangada J, Pearson T, Brehm MA, Wicker LS, Peterson LB, Shultz LD, Serreze DV, Rossini AA, Greiner DL.
Diabetes. 2009 Jan;58(1):165-73. Epub 2008 Nov 4.PMID: 18984741 [PubMed - indexed for MEDLINE]Related articlesFree article
Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.
Arefanian H, Tredget EB, Rajotte RV, Korbutt GS, Gill RG, Rayat GR.
Cell Transplant. 2007;16(8):787-98.PMID: 18087999 [PubMed - indexed for MEDLINE]Related articles
NOD mice have a generalized defect in their response to transplantation tolerance induction.
Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA.
Diabetes. 1999 May;48(5):967-74.PMID: 10331399 [PubMed - indexed for MEDLINE]Related articlesFree article
Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.
Phillips NE, Markees TG, Mordes JP, Greiner DL, Rossini AA.
J Immunol. 2003 Mar 15;170(6):3015-23.PMID: 12626555 [PubMed - indexed for MEDLINE]Related articlesFree article
Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation.
Molano RD, Berney T, Li H, Cattan P, Pileggi A, Vizzardelli C, Kenyon NS, Ricordi C, Burkly LC, Inverardi L.
Diabetes. 2001 Feb;50(2):270-6.PMID: 11272136 [PubMed - indexed for MEDLINE]Related articlesFree article
Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice.
Makhlouf L, Grey ST, Dong V, Csizmadia E, Arvelo MB, Auchincloss H Jr, Ferran C, Sayegh MH.
Transplantation. 2004 Apr 15;77(7):990-7.PMID: 15087759 [PubMed - indexed for MEDLINE]Related articles
Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis.
Shimizu K, Schönbeck U, Mach F, Libby P, Mitchell RN.
J Immunol. 2000 Sep 15;165(6):3506-18.PMID: 10975872 [PubMed - indexed for MEDLINE]Related articlesFree article
Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA.
Transplantation. 2004 May 15;77(9):1341-9.PMID: 15167588 [PubMed - indexed for MEDLINE]Related articles
Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation.
Guo L, Fujino M, Kimura H, Funeshima N, Kitazawa Y, Harihara Y, Tezuka K, Makuuchi M, Suzuki S, Li XK.
Transpl Immunol. 2003 Oct-Nov;12(1):41-8.PMID: 14551031 [PubMed - indexed for MEDLINE]Related articles
Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
Banuelos SJ, Markees TG, Phillips NE, Appel MC, Cuthbert A, Leif J, Mordes JP, Shultz LD, Rossini AA, Greiner DL.
Transplantation. 2004 Sep 15;78(5):660-7.PMID: 15371665 [PubMed - indexed for MEDLINE]Related articles
Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice.
Seung E, Iwakoshi N, Woda BA, Markees TG, Mordes JP, Rossini AA, Greiner DL.
Blood. 2000 Mar 15;95(6):2175-82.PMID: 10706892 [PubMed - indexed for MEDLINE]Related articlesFree article
CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression.
Honey K, Cobbold SP, Waldmann H.
J Immunol. 1999 Nov 1;163(9):4805-10.PMID: 10528180 [PubMed - indexed for MEDLINE]Related articlesFree article
Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic nod mice from autoimmune destruction and allogeneic and xenogeneic graft rejection.
Guo Z, Wu T, Kirchhof N, Mital D, Williams JW, Azuma M, Sutherland DE, Hering BJ.
Transplantation. 2001 Jun 15;71(11):1656-65.PMID: 11435979 [PubMed - indexed for MEDLINE]Related articles
CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.
Zheng XX, Markees TG, Hancock WW, Li Y, Greiner DL, Li XC, Mordes JP, Sayegh MH, Rossini AA, Strom TB.
J Immunol. 1999 Apr 15;162(8):4983-90.PMID: 10202046 [PubMed - indexed for MEDLINE]Related articlesFree article
Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade.
Guillonneau C, Aubry V, Renaudin K, Séveno C, Usal C, Tezuka K, Anegon I.
Transplantation. 2005 Aug 27;80(4):546-54.PMID: 16220623 [PubMed - indexed for MEDLINE]Related articles
Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
Pearson T, Weiser P, Markees TG, Serreze DV, Wicker LS, Peterson LB, Cumisky AM, Shultz LD, Mordes JP, Rossini AA, Greiner DL.
Diabetes. 2004 Aug;53(8):1972-8.PMID: 15277375 [PubMed - indexed for MEDLINE]Related articlesFree article
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