PubMed

Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study.

Mastbergen SC, Jansen NW, Bijlsma JW, Lafeber FP.

Arthritis Res Ther. 2006;8(1):R2.PMID: 16356188 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective COX-2 inhibition is favorable to human early and late-stage osteoarthritic cartilage: a human in vitro study.

Mastbergen SC, Bijlsma JW, Lafeber FP.

Osteoarthritis Cartilage. 2005 Jun;13(6):519-26.PMID: 15922186 [PubMed - indexed for MEDLINE]Related articles

Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro.

Jeffrey JE, Aspden RM.

Arthritis Res Ther. 2007;9(6):R129.PMID: 18096078 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and release of human cartilage matrix proteoglycans are differently regulated by nitric oxide and prostaglandin-E2.

Mastbergen SC, Bijlsma JW, Lafeber FP.

Ann Rheum Dis. 2008 Jan;67(1):52-8. Epub 2007 May 7.PMID: 17485421 [PubMed - indexed for MEDLINE]Related articles

The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment.

de Boer TN, Huisman AM, Polak AA, Niehoff AG, van Rinsum AC, Saris D, Bijlsma JW, Lafeber FJ, Mastbergen SC.

Osteoarthritis Cartilage. 2009 Apr;17(4):482-8. Epub 2008 Oct 15.PMID: 18926729 [PubMed - indexed for MEDLINE]Related articles

Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis.

Alvarez-Soria MA, Herrero-Beaumont G, Moreno-Rubio J, Calvo E, Santillana J, Egido J, Largo R.

Osteoarthritis Cartilage. 2008 Dec;16(12):1484-93. Epub 2008 Jun 10.PMID: 18547825 [PubMed - indexed for MEDLINE]Related articles

Inhibition of COX-2 by celecoxib in the canine groove model of osteoarthritis.

Mastbergen SC, Marijnissen AC, Vianen ME, Zoer B, van Roermund PM, Bijlsma JW, Lafeber FP.

Rheumatology (Oxford). 2006 Apr;45(4):405-13. Epub 2005 Nov 15.PMID: 16287921 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants.

Hardy MM, Seibert K, Manning PT, Currie MG, Woerner BM, Edwards D, Koki A, Tripp CS.

Arthritis Rheum. 2002 Jul;46(7):1789-803.PMID: 12124863 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of meloxicam, compared with other NSAIDs, on cartilage proteoglycan metabolism, synovial prostaglandin E2, and production of interleukins 1, 6 and 8, in human and porcine explants in organ culture.

Rainsford KD, Ying C, Smith FC.

J Pharm Pharmacol. 1997 Oct;49(10):991-8.PMID: 9364409 [PubMed - indexed for MEDLINE]Related articles

Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast--comparison to its effects on osteoarthritic chondrocytes.

Alvarez-Soria MA, Herrero-Beaumont G, Sánchez-Pernaute O, Bellido M, Largo R.

Rheumatology (Oxford). 2008 May;47(5):627-33. Epub 2008 Mar 27.PMID: 18375401 [PubMed - indexed for MEDLINE]Related articles

Effects of R and S enantiomers and a racemic mixture of carprofen on the production and release of proteoglycan and prostaglandin E2 from equine chondrocytes and cartilage explants.

Armstrong S, Lees P.

Am J Vet Res. 1999 Jan;60(1):98-104.PMID: 9918155 [PubMed - indexed for MEDLINE]Related articles

Effects of diclofenac, aceclofenac and meloxicam on the metabolism of proteoglycans and hyaluronan in osteoarthritic human cartilage.

Blot L, Marcelis A, Devogelaer JP, Manicourt DH.

Br J Pharmacol. 2000 Dec;131(7):1413-21.PMID: 11090115 [PubMed - indexed for MEDLINE]Related articlesFree article

Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenac.

Alvarez-Soria MA, Largo R, Santillana J, Sánchez-Pernaute O, Calvo E, Hernández M, Egido J, Herrero-Beaumont G.

Ann Rheum Dis. 2006 Aug;65(8):998-1005. Epub 2006 Feb 13.PMID: 16476713 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of SKI 306X, a new herbal agent, on proteoglycan degradation in cartilage explant culture and collagenase-induced rabbit osteoarthritis model.

Choi JH, Choi JH, Kim DY, Yoon JH, Youn HY, Yi JB, Rhee HI, Ryu KH, Jung K, Han CK, Kwak WJ, Cho YB.

Osteoarthritis Cartilage. 2002 Jun;10(6):471-8.PMID: 12056850 [PubMed - indexed for MEDLINE]Related articles

Effects of the NSAIDs meloxicam and indomethacin on cartilage proteoglycan synthesis and joint responses to calcium pyrophosphate crystals in dogs.

Rainsford KD, Skerry TM, Chindemi P, Delaney K.

Vet Res Commun. 1999 Mar;23(2):101-13.PMID: 10359154 [PubMed - indexed for MEDLINE]Related articles

Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs.

Sanchez C, Mateus MM, Defresne MP, Crielaard JM, Reginster JY, Henrotin YE.

J Rheumatol. 2002 Apr;29(4):772-82.PMID: 11950021 [PubMed - indexed for MEDLINE]Related articles

Nonsteroidal antiinflammatory drugs in treatment of osteoarthritis.

Brandt KD, Slowman-Kovacs S.

Clin Orthop Relat Res. 1986 Dec;(213):84-91.PMID: 3780106 [PubMed - indexed for MEDLINE]Related articles

Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage.

Mastbergen SC, Lafeber FP, Bijlsma JW.

Rheumatology (Oxford). 2002 Jul;41(7):801-8.PMID: 12096231 [PubMed - indexed for MEDLINE]Related articlesFree article

Do NSAIDs affect the progression of osteoarthritis?

Ding C.

Inflammation. 2002 Jun;26(3):139-42. Review.PMID: 12083420 [PubMed - indexed for MEDLINE]Related articles

Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.

Muscará MN, McKnight W, Asfaha S, Wallace JL.

Br J Pharmacol. 2000 Feb;129(4):681-6.PMID: 10683192 [PubMed - indexed for MEDLINE]Related articlesFree article