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    Results: 1 to 20 of 103

    1.

    Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.

    Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ.

    J Neuroinflammation. 2005 Dec 7;2:28.PMID: 16332263 [PubMed]Related articlesFree article

    2.

    Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice.

    Petrushina I, Ghochikyan A, Mkrtichyan M, Mamikonyan G, Movsesyan N, Ajdari R, Vasilevko V, Karapetyan A, Lees A, Agadjanyan MG, Cribbs DH.

    J Neuroinflammation. 2008 Sep 29;5:42.PMID: 18823564 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice.

    Petrushina I, Ghochikyan A, Mktrichyan M, Mamikonyan G, Movsesyan N, Davtyan H, Patel A, Head E, Cribbs DH, Agadjanyan MG.

    J Neurosci. 2007 Nov 14;27(46):12721-31.PMID: 18003852 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages.

    Asuni AA, Boutajangout A, Scholtzova H, Knudsen E, Li YS, Quartermain D, Frangione B, Wisniewski T, Sigurdsson EM.

    Eur J Neurosci. 2006 Nov;24(9):2530-42.PMID: 17100841 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice.

    Stahl T, Reimers C, Johne R, Schliebs R, Seeger J.

    Eur J Neurosci. 2006 Oct;24(7):1923-34.PMID: 17067295 [PubMed - indexed for MEDLINE]Related articles

    6.

    A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain.

    Sarsoza F, Saing T, Kayed R, Dahlin R, Dick M, Broadwater-Hollifield C, Mobley S, Lott I, Doran E, Gillen D, Anderson-Bergman C, Cribbs DH, Glabe C, Head E.

    Acta Neuropathol. 2009 Oct;118(4):505-17. Epub 2009 Apr 10.PMID: 19360426 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Novel Abeta immunogens: is shorter better?

    Lemere CA, Maier M, Peng Y, Jiang L, Seabrook TJ.

    Curr Alzheimer Res. 2007 Sep;4(4):427-36. Review.PMID: 17908047 [PubMed - indexed for MEDLINE]Related articles

    8.

    Reduced oligomeric and vascular amyloid-beta following immunization of TgCRND8 mice with an Alzheimer's DNA vaccine.

    DaSilva KA, Brown ME, McLaurin J.

    Vaccine. 2009 Feb 25;27(9):1365-76. Epub 2009 Jan 14.PMID: 19150380 [PubMed - indexed for MEDLINE]Related articles

    9.

    Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.

    Watson D, Castaño E, Kokjohn TA, Kuo YM, Lyubchenko Y, Pinsky D, Connolly ES Jr, Esh C, Luehrs DC, Stine WB, Rowse LM, Emmerling MR, Roher AE.

    Neurol Res. 2005 Dec;27(8):869-81. Review.PMID: 16354549 [PubMed - indexed for MEDLINE]Related articles

    10.

    Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response.

    Maier M, Seabrook TJ, Lazo ND, Jiang L, Das P, Janus C, Lemere CA.

    J Neurosci. 2006 May 3;26(18):4717-28.PMID: 16672644 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model.

    Levites Y, Das P, Price RW, Rochette MJ, Kostura LA, McGowan EM, Murphy MP, Golde TE.

    J Clin Invest. 2006 Jan;116(1):193-201. Epub 2005 Dec 8.PMID: 16341263 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage.

    Nikolic WV, Bai Y, Obregon D, Hou H, Mori T, Zeng J, Ehrhart J, Shytle RD, Giunta B, Morgan D, Town T, Tan J.

    Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2507-12. Epub 2007 Jan 30.PMID: 17264212 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid.

    Fan R, Xu F, Previti ML, Davis J, Grande AM, Robinson JK, Van Nostrand WE.

    J Neurosci. 2007 Mar 21;27(12):3057-63.PMID: 17376966 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice.

    Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE.

    J Neurosci. 2008 May 14;28(20):5312-20.PMID: 18480287 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: lessons from mice, monkeys, and humans.

    Lemere CA, Maier M, Jiang L, Peng Y, Seabrook TJ.

    Rejuvenation Res. 2006 Spring;9(1):77-84. Review.PMID: 16608400 [PubMed - indexed for MEDLINE]Related articles

    16.

    Novel approaches for immunotherapeutic intervention in Alzheimer's disease.

    Vasilevko V, Cribbs DH.

    Neurochem Int. 2006 Jul;49(2):113-26. Epub 2006 Jun 12. Review.PMID: 16765487 [PubMed - indexed for MEDLINE]Related articles

    17.

    Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.

    Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA.

    J Neurosci. 2008 Jun 18;28(25):6333-41.PMID: 18562603 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Amelioration of amyloid load by anti-Abeta single-chain antibody in Alzheimer mouse model.

    Fukuchi K, Accavitti-Loper MA, Kim HD, Tahara K, Cao Y, Lewis TL, Caughey RC, Kim H, Lalonde R.

    Biochem Biophys Res Commun. 2006 May 26;344(1):79-86.PMID: 16630540 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Vaccination as a therapeutic approach to Alzheimer's disease.

    Wisniewski T, Boutajangout A.

    Mt Sinai J Med. 2010 Jan;77(1):17-31.PMID: 20101719 [PubMed - in process]Related articles

    20.

    Dendrimeric Abeta1-15 is an effective immunogen in wildtype and APP-tg mice.

    Seabrook TJ, Thomas K, Jiang L, Bloom J, Spooner E, Maier M, Bitan G, Lemere CA.

    Neurobiol Aging. 2007 Jun;28(6):813-23. Epub 2006 May 24.PMID: 16725229 [PubMed - indexed for MEDLINE]Related articles

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