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    Results: 1 to 20 of 166

    1.

    Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.

    Kowluru A, Veluthakal R.

    Diabetes. 2005 Dec;54(12):3523-9.PMID: 16306371 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins.

    Amin RH, Chen HQ, Veluthakal R, Silver RB, Li J, Li G, Kowluru A.

    Endocrinology. 2003 Oct;144(10):4508-18. Epub 2003 Jun 19.PMID: 12960065 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.

    Kowluru A, Seavey SE, Li G, Sorenson RL, Weinhaus AJ, Nesher R, Rabaglia ME, Vadakekalam J, Metz SA.

    J Clin Invest. 1996 Jul 15;98(2):540-55.PMID: 8755667 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells.

    Veluthakal R, Kaur H, Goalstone M, Kowluru A.

    Diabetes. 2007 Jan;56(1):204-10.PMID: 17192483 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells.

    Veluthakal R, Madathilparambil SV, McDonald P, Olson LK, Kowluru A.

    Biochem Pharmacol. 2009 Jan 1;77(1):101-13. Epub 2008 Sep 27.PMID: 18930714 [PubMed - indexed for MEDLINE]Related articles

    6.

    Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells.

    Li J, Luo R, Kowluru A, Li G.

    Am J Physiol Endocrinol Metab. 2004 May;286(5):E818-27. Epub 2004 Jan 21.PMID: 14736704 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Evidence for differential roles of the Rho subfamily of GTP-binding proteins in glucose- and calcium-induced insulin secretion from pancreatic beta cells.

    Kowluru A, Li G, Rabaglia ME, Segu VB, Hofmann F, Aktories K, Metz SA.

    Biochem Pharmacol. 1997 Nov 15;54(10):1097-108.PMID: 9464452 [PubMed - indexed for MEDLINE]Related articles

    9.

    Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.

    Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S.

    Endocrinology. 2005 Aug;146(8):3266-76. Epub 2005 May 5.PMID: 15878969 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Mutated D4-guanine diphosphate-dissociation inhibitor is found in human leukemic cells and promotes leukemic cell invasion.

    Nakata Y, Kondoh K, Fukushima S, Hashiguchi A, Du W, Hayashi M, Fujimoto J, Hata J, Yamada T.

    Exp Hematol. 2008 Jan;36(1):37-50. Epub 2007 Nov 26.PMID: 18037226 [PubMed - indexed for MEDLINE]Related articles

    11.

    Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential.

    Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P.

    Int J Biochem Cell Biol. 2008;40(8):1522-35. Epub 2007 Dec 3.PMID: 18248766 [PubMed - indexed for MEDLINE]Related articles

    12.

    Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion.

    Wang Z, Oh E, Thurmond DC.

    J Biol Chem. 2007 Mar 30;282(13):9536-46. Epub 2007 Feb 8.PMID: 17289663 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.

    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.

    Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1354-62. Epub 2009 Mar 17.PMID: 19293334 [PubMed - indexed for MEDLINE]Related articles

    14.

    Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation.

    Amin R, Chen HQ, Tannous M, Gibbs R, Kowluru A.

    J Pharmacol Exp Ther. 2002 Oct;303(1):82-8.PMID: 12235236 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.

    Sun Y, Zhang L, Gu HF, Han W, Ren M, Wang F, Gong B, Wang L, Guo H, Xin W, Zhao J, Gao L.

    Endocrinology. 2008 Feb;149(2):662-71. Epub 2007 Nov 8.PMID: 17991720 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion.

    Kowluru A.

    Biochem Pharmacol. 2002 Jun 15;63(12):2091-100.PMID: 12110368 [PubMed - indexed for MEDLINE]Related articles

    17.

    Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.

    Ramanadham S, Song H, Hsu FF, Zhang S, Crankshaw M, Grant GA, Newgard CB, Bao S, Ma Z, Turk J.

    Biochemistry. 2003 Dec 2;42(47):13929-40.PMID: 14636061 [PubMed - indexed for MEDLINE]Related articles

    18.

    A role for G(z) in pancreatic islet beta-cell biology.

    Kimple ME, Nixon AB, Kelly P, Bailey CL, Young KH, Fields TA, Casey PJ.

    J Biol Chem. 2005 Sep 9;280(36):31708-13. Epub 2005 Jul 6.PMID: 16157560 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

    Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB.

    Proc Natl Acad Sci U S A. 2005 May 17;102(20):7297-302. Epub 2005 May 9.PMID: 15883383 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.

    Kowluru A.

    J Cell Mol Med. 2008 Jan-Feb;12(1):164-73. Epub 2007 Dec 5. Review.PMID: 18053094 [PubMed - indexed for MEDLINE]Related articles

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