PubMed

Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.

Schupp M, Clemenz M, Gineste R, Witt H, Janke J, Helleboid S, Hennuyer N, Ruiz P, Unger T, Staels B, Kintscher U.

Diabetes. 2005 Dec;54(12):3442-52.PMID: 16306360 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.

Schupp M, Janke J, Clasen R, Unger T, Kintscher U.

Circulation. 2004 May 4;109(17):2054-7. Epub 2004 Apr 26.PMID: 15117841 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin.

Clasen R, Schupp M, Foryst-Ludwig A, Sprang C, Clemenz M, Krikov M, Thöne-Reineke C, Unger T, Kintscher U.

Hypertension. 2005 Jul;46(1):137-43. Epub 2005 Jun 6.PMID: 15939809 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.

Benson SC, Pershadsingh HA, Ho CI, Chittiboyina A, Desai P, Pravenec M, Qi N, Wang J, Avery MA, Kurtz TW.

Hypertension. 2004 May;43(5):993-1002. Epub 2004 Mar 8.PMID: 15007034 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.

Scalera F, Martens-Lobenhoffer J, Bukowska A, Lendeckel U, Täger M, Bode-Böger SM.

Hypertension. 2008 Mar;51(3):696-703. Epub 2008 Feb 4.PMID: 18250362 [PubMed - indexed for MEDLINE]Related articlesFree article

A selective peroxisome proliferator-activated receptor-gamma modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones.

Tagami T, Yamamoto H, Moriyama K, Sawai K, Usui T, Shimatsu A, Naruse M.

Endocrinology. 2009 Feb;150(2):862-70. Epub 2009 Jan 15.PMID: 19147680 [PubMed - indexed for MEDLINE]Related articles

Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation.

Janke J, Schupp M, Engeli S, Gorzelniak K, Boschmann M, Sauma L, Nystrom FH, Jordan J, Luft FC, Sharma AM.

J Hypertens. 2006 Sep;24(9):1809-16.PMID: 16915030 [PubMed - indexed for MEDLINE]Related articles

A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties.

Fujimura T, Kimura C, Oe T, Takata Y, Sakuma H, Aramori I, Mutoh S.

J Pharmacol Exp Ther. 2006 Aug;318(2):863-71. Epub 2006 May 8.PMID: 16682454 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites.

Schupp M, Lee LD, Frost N, Umbreen S, Schmidt B, Unger T, Kintscher U.

Hypertension. 2006 Mar;47(3):586-9. Epub 2005 Dec 19.PMID: 16365190 [PubMed - indexed for MEDLINE]Related articlesFree article

Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists: beyond the renin-angiotensin system.

Kurtz TW, Pravenec M.

J Hypertens. 2004 Dec;22(12):2253-61. Review.PMID: 15614015 [PubMed - indexed for MEDLINE]Related articles

Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator-activated receptor-gamma-modulating activity, on nitric oxide bioavailability and atherosclerotic change.

Ikejima H, Imanishi T, Tsujioka H, Kuroi A, Kobayashi K, Shiomi M, Muragaki Y, Mochizuki S, Goto M, Yoshida K, Akasaka T.

J Hypertens. 2008 May;26(5):964-72.PMID: 18398339 [PubMed - indexed for MEDLINE]Related articles

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.

Clemenz M, Frost N, Schupp M, Caron S, Foryst-Ludwig A, Böhm C, Hartge M, Gust R, Staels B, Unger T, Kintscher U.

Diabetes. 2008 May;57(5):1405-13. Epub 2008 Jan 9.PMID: 18184928 [PubMed - indexed for MEDLINE]Related articlesFree article

Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property.

Yamagishi S, Takeuchi M.

Med Hypotheses. 2005;64(3):476-8.PMID: 15617852 [PubMed - indexed for MEDLINE]Related articles

A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.

Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.

Eur J Pharmacol. 2008 Apr 14;584(1):192-201. Epub 2008 Feb 14.PMID: 18346728 [PubMed - indexed for MEDLINE]Related articles

Angiotensin inhibition stimulates PPARgamma and the release of visfatin.

Storka A, Vojtassakova E, Mueller M, Kapiotis S, Haider DG, Jungbauer A, Wolzt M.

Eur J Clin Invest. 2008 Nov;38(11):820-6.PMID: 19021699 [PubMed - indexed for MEDLINE]Related articles

Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-gamma.

Pershadsingh HA.

Int J Biochem Cell Biol. 2006;38(5-6):766-81. Epub 2005 Sep 9. Review.PMID: 16298156 [PubMed - indexed for MEDLINE]Related articles

Treating the metabolic syndrome: telmisartan as a peroxisome proliferator-activated receptor-gamma activator.

Kurtz TW.

Acta Diabetol. 2005 Apr;42 Suppl 1:S9-16. Review.PMID: 15868121 [PubMed - indexed for MEDLINE]Related articles

Beyond the classic angiotensin-receptor-blocker profile.

Kurtz TW.

Nat Clin Pract Cardiovasc Med. 2008 Jul;5 Suppl 1:S19-26. Review.PMID: 18580862 [PubMed - indexed for MEDLINE]Related articles

Inhibition of cardiovascular cell proliferation by angiotensin receptor blockers: are all molecules the same?

Benson SC, Iguchi R, Ho CI, Yamamoto K, Kurtz TW.

J Hypertens. 2008 May;26(5):973-80.PMID: 18398340 [PubMed - indexed for MEDLINE]Related articles

Telmisartan downregulates angiotensin II type 1 receptor through activation of peroxisome proliferator-activated receptor gamma.

Imayama I, Ichiki T, Inanaga K, Ohtsubo H, Fukuyama K, Ono H, Hashiguchi Y, Sunagawa K.

Cardiovasc Res. 2006 Oct 1;72(1):184-90. Epub 2006 Jul 21.PMID: 16938288 [PubMed - indexed for MEDLINE]Related articlesFree article