PubMed

Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.

Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA.

Diabetes. 2005 Dec;54(12):3435-41.PMID: 16306359 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.

Drel VR, Pacher P, Stevens MJ, Obrosova IG.

Free Radic Biol Med. 2006 Apr 15;40(8):1454-65. Epub 2006 Jan 31.PMID: 16631535 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.

Obrosova IG, Pacher P, Szabó C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA.

Diabetes. 2005 Jan;54(1):234-42.PMID: 15616034 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.

Ilnytska O, Lyzogubov VV, Stevens MJ, Drel VR, Mashtalir N, Pacher P, Yorek MA, Obrosova IG.

Diabetes. 2006 Jun;55(6):1686-94.PMID: 16731831 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.

Obrosova IG, Li F, Abatan OI, Forsell MA, Komjáti K, Pacher P, Szabó C, Stevens MJ.

Diabetes. 2004 Mar;53(3):711-20.PMID: 14988256 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.

Drel VR, Xu W, Zhang J, Kador PF, Ali TK, Shin J, Julius U, Slusher B, El-Remessy AB, Obrosova IG.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1778-90. Epub 2008 Dec 20.PMID: 19098320 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats.

Stevens MJ, Li F, Drel VR, Abatan OI, Kim H, Burnett D, Larkin D, Obrosova IG.

J Pharmacol Exp Ther. 2007 Jan;320(1):458-64. Epub 2006 Oct 4.PMID: 17021258 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

Obrosova IG, Minchenko AG, Frank RN, Seigel GM, Zsengeller Z, Pacher P, Stevens MJ, Szabó C.

Int J Mol Med. 2004 Jul;14(1):55-64.PMID: 15202016 [PubMed - indexed for MEDLINE]Related articles

Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.

Minchenko AG, Stevens MJ, White L, Abatan OI, Komjáti K, Pacher P, Szabó C, Obrosova IG.

FASEB J. 2003 Aug;17(11):1514-6. Epub 2003 Jun 3.PMID: 12824290 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

Drel VR, Pacher P, Ali TK, Shin J, Julius U, El-Remessy AB, Obrosova IG.

Int J Mol Med. 2008 Jun;21(6):667-76.PMID: 18506358 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy.

Kuchmerovska T, Shymanskyy I, Donchenko G, Kuchmerovskyy M, Pakirbaieva L, Klimenko A.

J Diabetes Complications. 2004 Jul-Aug;18(4):198-204.PMID: 15207836 [PubMed - indexed for MEDLINE]Related articles

Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus.

Horváth EM, Benko R, Kiss L, Murányi M, Pék T, Fekete K, Bárány T, Somlai A, Csordás A, Szabo C.

Diabetologia. 2009 May;52(5):952-61. Epub 2009 Mar 5.PMID: 19263033 [PubMed - indexed for MEDLINE]Related articles

The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity.

Kiss L, Szabó C.

Mem Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:29-37. Epub 2005 Jun 14. Review.PMID: 15962096 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress-induced, poly(ADP-ribose) polymerase-dependent upregulation of ET-1 expression in chronic diabetic complications.

Chiu J, Xu BY, Chen S, Feng B, Chakrabarti S.

Can J Physiol Pharmacol. 2008 Jun;86(6):365-72.PMID: 18516100 [PubMed - indexed for MEDLINE]Related articles

Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.

Li F, Szabó C, Pacher P, Southan GJ, Abatan OI, Charniauskaya T, Stevens MJ, Obrosova IG.

Diabetologia. 2004 Apr;47(4):710-7.PMID: 15298348 [PubMed - indexed for MEDLINE]Related articles

Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.

Li F, Drel VR, Szabó C, Stevens MJ, Obrosova IG.

Diabetes. 2005 May;54(5):1514-22.PMID: 15855340 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.

Pacher P, Obrosova IG, Mabley JG, Szabó C.

Curr Med Chem. 2005;12(3):267-75. Review.PMID: 15723618 [PubMed - indexed for MEDLINE]Related articlesFree article

Deleterious activation of poly(ADP-ribose)polymerase-1 in brain after in vivo oxidative stress.

Besson VC, Margaill I, Plotkine M, Marchand-Verrecchia C.

Free Radic Res. 2003 Nov;37(11):1201-8.PMID: 14703732 [PubMed - indexed for MEDLINE]Related articles

Metformin suppresses high glucose-induced poly(adenosine diphosphate-ribose) polymerase overactivation in aortic endothelial cells.

Mahrouf-Yorgov M, Marie N, Borderie D, Djelidi R, Bonnefont-Rousselot D, Legrand A, Beaudeux JL, Peynet J.

Metabolism. 2009 Apr;58(4):525-33.PMID: 19303974 [PubMed - indexed for MEDLINE]Related articles

Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.

Obrosova IG, Drel VR, Oltman CL, Mashtalir N, Tibrewala J, Groves JT, Yorek MA.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1645-55. Epub 2007 Oct 2.PMID: 17911342 [PubMed - indexed for MEDLINE]Related articlesFree article