PubMed

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.

Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von Boehmer H, Mahnke K, Buer J.

Diabetes. 2005 Dec;54(12):3395-401.PMID: 16306354 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanisms involved in experimental insulin-dependent diabetes mellitus.

Radu DL.

Roum Arch Microbiol Immunol. 2001 Jul-Sep;60(3):203-26.PMID: 12165974 [PubMed - indexed for MEDLINE]Related articles

Intestinal epithelial antigen induces CD4+ T cells with regulatory phenotype in a transgenic autoimmune mouse model.

Westendorf AM, Bruder D, Hansen W, Buer J.

Ann N Y Acad Sci. 2006 Aug;1072:401-6.PMID: 17057222 [PubMed - indexed for MEDLINE]Related articles

CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells.

Mariño E, Villanueva J, Walters S, Liuwantara D, Mackay F, Grey ST.

Diabetes. 2009 Jul;58(7):1568-77. Epub 2009 Mar 31.PMID: 19336675 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM.

J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8.PMID: 17210729 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic administration of agonist peptide blocks the progression of spontaneous CD8-mediated autoimmune diabetes in transgenic mice without bystander damage.

Bercovici N, Heurtier A, Vizler C, Pardigon N, Cambouris C, Desreumaux P, Liblau R.

J Immunol. 2000 Jul 1;165(1):202-10.PMID: 10861053 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation.

Westendorf AM, Templin M, Geffers R, Deppenmeier S, Gruber AD, Probst-Kepper M, Hansen W, Liblau RS, Gunzer F, Bruder D, Buer J.

Gut. 2005 Jan;54(1):60-9.PMID: 15591505 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K.

Gastroenterology. 2008 Apr;134(4):1028-37. Epub 2008 Jan 30.PMID: 18395084 [PubMed - indexed for MEDLINE]Related articles

Ontogeny of T cell tolerance to peripherally expressed antigens.

Morgan DJ, Kurts C, Kreuwel HT, Holst KL, Heath WR, Sherman LA.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3854-8.PMID: 10097127 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.

Luo X, Tarbell KV, Yang H, Pothoven K, Bailey SL, Ding R, Steinman RM, Suthanthiran M.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2821-6. Epub 2007 Feb 16.PMID: 17307871 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells.

Westendorf AM, Fleissner D, Deppenmeier S, Gruber AD, Bruder D, Hansen W, Liblau R, Buer J.

Gastroenterology. 2006 Aug;131(2):510-24.PMID: 16890605 [PubMed - indexed for MEDLINE]Related articles

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6374-9. Epub 2008 Apr 22.PMID: 18430797 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity.

Scott B, Liblau R, Degermann S, Marconi LA, Ogata L, Caton AJ, McDevitt HO, Lo D.

Immunity. 1994 Apr;1(1):73-83.PMID: 7889402 [PubMed - indexed for MEDLINE]Related articles

Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells.

Mahnke K, Qian Y, Knop J, Enk AH.

Blood. 2003 Jun 15;101(12):4862-9. Epub 2003 Jan 23.PMID: 12543858 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells.

DiPaolo RJ, Brinster C, Davidson TS, Andersson J, Glass D, Shevach EM.

J Immunol. 2007 Oct 1;179(7):4685-93.PMID: 17878367 [PubMed - indexed for MEDLINE]Related articlesFree article

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.

Gaudreau S, Guindi C, Ménard M, Besin G, Dupuis G, Amrani A.

J Immunol. 2007 Sep 15;179(6):3638-47.PMID: 17785799 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo.

Weber SE, Harbertson J, Godebu E, Mros GA, Padrick RC, Carson BD, Ziegler SF, Bradley LM.

J Immunol. 2006 Apr 15;176(8):4730-9.PMID: 16585566 [PubMed - indexed for MEDLINE]Related articlesFree article

Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development.

Ford MS, Chen W, Wong S, Li C, Vanama R, Elford AR, Asa SL, Ohashi PS, Zhang L.

Eur J Immunol. 2007 Aug;37(8):2234-41.PMID: 17578845 [PubMed - indexed for MEDLINE]Related articles

Protection against diabetes by MHC heterozygosity and reversal by cyclophosphamide.

Wu AY, Schulman SJ, Marconi LA, Reilly CR, Scott B, Lo D.

Cell Immunol. 1998 Mar 15;184(2):112-20.PMID: 9630837 [PubMed - indexed for MEDLINE]Related articles

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.

Piaggio E, Mars LT, Cassan C, Cabarrocas J, Hofstätter M, Desbois S, Bergereau E, Rötzschke O, Falk K, Liblau RS.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9393-8. Epub 2007 May 16.PMID: 17517665 [PubMed - indexed for MEDLINE]Related articlesFree article