PubMed

Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination.

Tsuchida A, Yamauchi T, Takekawa S, Hada Y, Ito Y, Maki T, Kadowaki T.

Diabetes. 2005 Dec;54(12):3358-70.PMID: 16306350 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.

Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M.

Endocrinology. 2006 Sep;147(9):4517-24. Epub 2006 Jun 1.PMID: 16740970 [PubMed - indexed for MEDLINE]Related articlesFree article

The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo.

Li YY, Wu HS, Tang L, Feng CR, Yu JH, Li Y, Yang YS, Yang B, He QJ.

Pharmacol Res. 2007 Oct;56(4):335-43. Epub 2007 Aug 9.PMID: 17889553 [PubMed - indexed for MEDLINE]Related articles

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.

Diabetes. 2008 Aug;57(8):1999-2011. Epub 2008 May 5.PMID: 18458147 [PubMed - indexed for MEDLINE]Related articlesFree article

Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, E3030, in db/db mice and beagle dogs.

Kasai S, Inoue T, Yoshitomi H, Hihara T, Matsuura F, Harada H, Shinoda M, Tanaka I.

J Pharmacol Sci. 2008 Sep;108(1):40-8. Epub 2008 Sep 6.PMID: 18776709 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment.

Takasawa K, Kubota N, Terauchi Y, Kadowaki T.

Endocr J. 2008 Aug;55(4):767-76. Epub 2008 May 28.PMID: 18506083 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice.

Edvardsson U, Bergström M, Alexandersson M, Bamberg K, Ljung B, Dahllöf B.

J Lipid Res. 1999 Jul;40(7):1177-84.PMID: 10393202 [PubMed - indexed for MEDLINE]Related articlesFree article

A peroxisome proliferator-activated receptor alpha/gamma dual agonist with a unique in vitro profile and potent glucose and lipid effects in rodent models of type 2 diabetes and dyslipidemia.

Reifel-Miller A, Otto K, Hawkins E, Barr R, Bensch WR, Bull C, Dana S, Klausing K, Martin JA, Rafaeloff-Phail R, Rafizadeh-Montrose C, Rhodes G, Robey R, Rojo I, Rungta D, Snyder D, Wilbur K, Zhang T, Zink R, Warshawsky A, Brozinick JT.

Mol Endocrinol. 2005 Jun;19(6):1593-605. Epub 2005 Apr 14.PMID: 15831517 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of PPAR-alpha and -gamma agonist on the expression of visfatin, adiponectin, and TNF-alpha in visceral fat of OLETF rats.

Choi KC, Ryu OH, Lee KW, Kim HY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):747-53.PMID: 16157299 [PubMed - indexed for MEDLINE]Related articles

A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.

Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.

Eur J Pharmacol. 2008 Apr 14;584(1):192-201. Epub 2008 Feb 14.PMID: 18346728 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice.

Verreth W, Ganame J, Mertens A, Bernar H, Herregods MC, Holvoet P.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):922-8. Epub 2006 Feb 2.PMID: 16456093 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism by which a novel non-thiazolidinedione peroxisome proliferator-activated receptor gamma agonist, FK614, ameliorates insulin resistance in Zucker fatty rats.

Minoura H, Takeshita S, Kimura C, Hirosumi J, Takakura S, Kawamura I, Seki J, Manda T, Mutoh S.

Diabetes Obes Metab. 2007 May;9(3):369-78.PMID: 17391165 [PubMed - indexed for MEDLINE]Related articles

Differential effects of contraction and PPAR agonists on the expression of fatty acid transporters in rat skeletal muscle.

Benton CR, Koonen DP, Calles-Escandon J, Tandon NN, Glatz JF, Luiken JJ, Heikkila JJ, Bonen A.

J Physiol. 2006 May 15;573(Pt 1):199-210. Epub 2006 Feb 16.PMID: 16484294 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue.

Guri AJ, Hontecillas R, Ferrer G, Casagran O, Wankhade U, Noble AM, Eizirik DL, Ortis F, Cnop M, Liu D, Si H, Bassaganya-Riera J.

J Nutr Biochem. 2008 Apr;19(4):216-28. Epub 2007 Jul 6.PMID: 17618105 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.

Stienstra R, Duval C, Keshtkar S, van der Laak J, Kersten S, Müller M.

J Biol Chem. 2008 Aug 15;283(33):22620-7. Epub 2008 Jun 9.PMID: 18541527 [PubMed - indexed for MEDLINE]Related articlesFree article

The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats.

Li PP, Shan S, Chen YT, Ning ZQ, Sun SJ, Liu Q, Lu XP, Xie MZ, Shen ZF.

Br J Pharmacol. 2006 Jul;148(5):610-8. Epub 2006 Jun 5.PMID: 16751799 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation.

Muhlhausler BS, Morrison JL, McMillen IC.

Endocrinology. 2009 Sep;150(9):4287-94. Epub 2009 Jun 11.PMID: 19520784 [PubMed - indexed for MEDLINE]Related articles

Pan-PPAR agonist beneficial effects in overweight mice fed a high-fat high-sucrose diet.

Fernandes-Santos C, Carneiro RE, de Souza Mendonca L, Aguila MB, Mandarim-de-Lacerda CA.

Nutrition. 2009 Jul-Aug;25(7-8):818-27. Epub 2009 Mar 5.PMID: 19268533 [PubMed - indexed for MEDLINE]Related articles

Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones.

Kaltenbach S, Staiger H, Weisser M, Haas C, Stumvoll M, Machicao F, Häring HU.

Int J Obes (Lond). 2005 Jul;29(7):760-5.PMID: 15824748 [PubMed - indexed for MEDLINE]Related articles

Dietary abscisic acid ameliorates glucose tolerance and obesity-related inflammation in db/db mice fed high-fat diets.

Guri AJ, Hontecillas R, Si H, Liu D, Bassaganya-Riera J.

Clin Nutr. 2007 Feb;26(1):107-16. Epub 2006 Sep 26.PMID: 17000034 [PubMed - indexed for MEDLINE]Related articles