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    Results: 1 to 20 of 144

    1.

    Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.

    Freude S, Plum L, Schnitker J, Leeser U, Udelhoven M, Krone W, Bruning JC, Schubert M.

    Diabetes. 2005 Dec;54(12):3343-8.PMID: 16306348 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Reduced insulin-induced phosphatidylinositol-3-kinase activation in peripheral blood mononuclear leucocytes from patients with Alzheimer's disease.

    Castri P, Iacovelli L, De Blasi A, Giubilei F, Moretti A, Capone FT, Nicoletti F, Orzi F.

    Eur J Neurosci. 2007 Nov;26(9):2469-72.PMID: 17986027 [PubMed - indexed for MEDLINE]Related articles

    3.

    Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.

    Clodfelder-Miller BJ, Zmijewska AA, Johnson GV, Jope RS.

    Diabetes. 2006 Dec;55(12):3320-5.PMID: 17130475 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice.

    Sawamura N, Gong JS, Garver WS, Heidenreich RA, Ninomiya H, Ohno K, Yanagisawa K, Michikawa M.

    J Biol Chem. 2001 Mar 30;276(13):10314-9. Epub 2001 Jan 4.PMID: 11152466 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin.

    Jolivalt CG, Lee CA, Beiswenger KK, Smith JL, Orlov M, Torrance MA, Masliah E.

    J Neurosci Res. 2008 Nov 15;86(15):3265-74.PMID: 18627032 [PubMed - indexed for MEDLINE]Related articles

    6.

    Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.

    Schubert M, Brazil DP, Burks DJ, Kushner JA, Ye J, Flint CL, Farhang-Fallah J, Dikkes P, Warot XM, Rio C, Corfas G, White MF.

    J Neurosci. 2003 Aug 6;23(18):7084-92.PMID: 12904469 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications.

    Deutsch SI, Rosse RB, Lakshman RM.

    Prog Neuropsychopharmacol Biol Psychiatry. 2006 Dec 30;30(8):1369-80. Epub 2006 Jun 21. Review.PMID: 16793187 [PubMed - indexed for MEDLINE]Related articles

    8.

    Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.

    Padmanabhan J, Levy M, Dickson DW, Potter H.

    Brain. 2006 Nov;129(Pt 11):3020-34. Epub 2006 Sep 20.PMID: 16987932 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms.

    Planel E, Tatebayashi Y, Miyasaka T, Liu L, Wang L, Herman M, Yu WH, Luchsinger JA, Wadzinski B, Duff KE, Takashima A.

    J Neurosci. 2007 Dec 12;27(50):13635-48.PMID: 18077675 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration.

    Ramesh Babu J, Lamar Seibenhener M, Peng J, Strom AL, Kemppainen R, Cox N, Zhu H, Wooten MC, Diaz-Meco MT, Moscat J, Wooten MW.

    J Neurochem. 2008 Jul;106(1):107-20. Epub 2008 Jul 1.PMID: 18346206 [PubMed - indexed for MEDLINE]Related articles

    11.

    Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease.

    Yanagisawa M, Planel E, Ishiguro K, Fujita SC.

    FEBS Lett. 1999 Nov 19;461(3):329-33.PMID: 10567721 [PubMed - indexed for MEDLINE]Related articles

    12.

    The role of insulin receptor signaling in the brain.

    Plum L, Schubert M, Brüning JC.

    Trends Endocrinol Metab. 2005 Mar;16(2):59-65. Review.PMID: 15734146 [PubMed - indexed for MEDLINE]Related articles

    13.

    Effect of cortistatin on tau phosphorylation at Ser262 site.

    Rubio A, Pérez M, de Lecea L, Avila J.

    J Neurosci Res. 2008 Aug 15;86(11):2462-75.PMID: 18438934 [PubMed - indexed for MEDLINE]Related articles

    14.

    Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

    Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM.

    J Alzheimers Dis. 2005 Feb;7(1):63-80.PMID: 15750215 [PubMed - indexed for MEDLINE]Related articles

    15.

    Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau.

    Meske V, Albert F, Ohm TG.

    J Biol Chem. 2008 Jan 4;283(1):100-9. Epub 2007 Oct 30.PMID: 17971449 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy").

    Busceti CL, Biagioni F, Riozzi B, Battaglia G, Storto M, Cinque C, Molinaro G, Gradini R, Caricasole A, Canudas AM, Bruno V, Nicoletti F, Fornai F.

    J Neurosci. 2008 Mar 19;28(12):3234-45.PMID: 18354027 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Tau is hyperphosphorylated in the insulin-like growth factor-I null brain.

    Cheng CM, Tseng V, Wang J, Wang D, Matyakhina L, Bondy CA.

    Endocrinology. 2005 Dec;146(12):5086-91. Epub 2005 Aug 25.PMID: 16123158 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism.

    Elliott E, Atlas R, Lange A, Ginzburg I.

    Eur J Neurosci. 2005 Sep;22(5):1081-9.PMID: 16176349 [PubMed - indexed for MEDLINE]Related articles

    19.

    The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system.

    Folli F, Ghidella S, Bonfanti L, Kahn CR, Merighi A.

    Mol Neurobiol. 1996 Oct;13(2):155-83. Review.PMID: 8938649 [PubMed - indexed for MEDLINE]Related articles

    20.

    Insulin glulisine: insulin receptor signaling characteristics in vivo.

    Hennige AM, Lehmann R, Weigert C, Moeschel K, Schäuble M, Metzinger E, Lammers R, Häring HU.

    Diabetes. 2005 Feb;54(2):361-6.PMID: 15677493 [PubMed - indexed for MEDLINE]Related articlesFree article

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