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Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes.

Hotamisligil GS.

Diabetes. 2005 Dec;54 Suppl 2:S73-8. Review.PMID: 16306344 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes.

Hotamisligil GS.

Novartis Found Symp. 2007;286:86-94; discussion 94-8, 162-3, 196-203.PMID: 18269176 [PubMed - indexed for MEDLINE]Related articles

Inflammation and endoplasmic reticulum stress in obesity and diabetes.

Hotamisligil GS.

Int J Obes (Lond). 2008 Dec;32 Suppl 7:S52-4. Review.PMID: 19136991 [PubMed - indexed for MEDLINE]Related articles

Inflammatory pathways and insulin action.

Hotamisligil GS.

Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S53-5. Review.PMID: 14704746 [PubMed - indexed for MEDLINE]Related articles

The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance.

Taniguchi CM, Aleman JO, Ueki K, Luo J, Asano T, Kaneto H, Stephanopoulos G, Cantley LC, Kahn CR.

Mol Cell Biol. 2007 Apr;27(8):2830-40. Epub 2007 Feb 5.PMID: 17283057 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of obesity and related pathology: linking immune responses to metabolic stress.

Karalis KP, Giannogonas P, Kodela E, Koutmani Y, Zoumakis M, Teli T.

FEBS J. 2009 Oct;276(20):5747-54. Epub 2009 Sep 15. Review.PMID: 19754872 [PubMed - indexed for MEDLINE]Related articles

Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic beta-cell dysfunction and insulin resistance.

Kaneto H, Nakatani Y, Kawamori D, Miyatsuka T, Matsuoka TA, Matsuhisa M, Yamasaki Y.

Int J Biochem Cell Biol. 2006;38(5-6):782-93. Review.PMID: 16607699 [PubMed - indexed for MEDLINE]Related articles

The role for endoplasmic reticulum stress in diabetes mellitus.

Eizirik DL, Cardozo AK, Cnop M.

Endocr Rev. 2008 Feb;29(1):42-61. Epub 2007 Nov 29. Review.PMID: 18048764 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic beta-cell dysfunction and insulin resistance.

Kaneto H, Nakatani Y, Kawamori D, Miyatsuka T, Matsuoka TA, Matsuhisa M, Yamasaki Y.

Int J Biochem Cell Biol. 2005 Aug;37(8):1595-608. Epub 2005 Apr 22. Review.PMID: 15878838 [PubMed - indexed for MEDLINE]Related articles

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS.

Science. 2004 Oct 15;306(5695):457-61.PMID: 15486293 [PubMed - indexed for MEDLINE]Related articlesFree article

Stress, the endoplasmic reticulum, and insulin resistance.

Tsiotra PC, Tsigos C.

Ann N Y Acad Sci. 2006 Nov;1083:63-76. Review.PMID: 17148734 [PubMed - indexed for MEDLINE]Related articles

CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.

Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE.

Hepatology. 2007 May;45(5):1108-17.PMID: 17464987 [PubMed - indexed for MEDLINE]Related articles

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease.

Gregor MF, Hotamisligil GS.

J Lipid Res. 2007 Sep;48(9):1905-14. Epub 2007 May 9. Review.PMID: 17699733 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.

Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH.

Mol Cell Biol. 2006 Apr;26(8):3071-84.PMID: 16581782 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity, inflammation, and insulin resistance--a mini-review.

Zeyda M, Stulnig TM.

Gerontology. 2009;55(4):379-86. Epub 2009 Apr 8. Review.PMID: 19365105 [PubMed - indexed for MEDLINE]Related articles

C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.

Strle K, Broussard SR, McCusker RH, Shen WH, LeCleir JM, Johnson RW, Freund GG, Dantzer R, Kelley KW.

Endocrinology. 2006 Sep;147(9):4363-73. Epub 2006 Jun 15.PMID: 16777978 [PubMed - indexed for MEDLINE]Related articlesFree article

JNK: a new therapeutic target for diabetes.

Bennett BL, Satoh Y, Lewis AJ.

Curr Opin Pharmacol. 2003 Aug;3(4):420-5. Review.PMID: 12901952 [PubMed - indexed for MEDLINE]Related articles

Inflammatory mechanisms in the regulation of insulin resistance.

Tilg H, Moschen AR.

Mol Med. 2008 Mar-Apr;14(3-4):222-31. Review.PMID: 18235842 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular inflammatory responses: novel insights for obesity and insulin resistance.

Chen H.

Pharmacol Res. 2006 Jun;53(6):469-77. Epub 2006 Mar 22. Review.PMID: 16632376 [PubMed - indexed for MEDLINE]Related articles

JNK: bridging the insulin signaling and inflammatory pathway.

Liu G, Rondinone CM.

Curr Opin Investig Drugs. 2005 Oct;6(10):979-87. Review. Erratum in: Curr Opin Investig Drugs. 2005 Dec;6(12):1280. PMID: 16259218 [PubMed - indexed for MEDLINE]Related articles