PubMed

Psammomys obesus, a model for environment-gene interactions in type 2 diabetes.

Kaiser N, Nesher R, Donath MY, Fraenkel M, Behar V, Magnan C, Ktorza A, Cerasi E, Leibowitz G.

Diabetes. 2005 Dec;54 Suppl 2:S137-44. Review.PMID: 16306331 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes.

Leibowitz G, Yuli M, Donath MY, Nesher R, Melloul D, Cerasi E, Gross DJ, Kaiser N.

Diabetes. 2001 Feb;50 Suppl 1:S113-7.PMID: 11272167 [PubMed - indexed for MEDLINE]Related articles

Dynamic changes in {beta}-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in psammomys obesus: impact of glycemic control.

Kaiser N, Yuli M, Uçkaya G, Oprescu AI, Berthault MF, Kargar C, Donath MY, Cerasi E, Ktorza A.

Diabetes. 2005 Jan;54(1):138-45.PMID: 15616021 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

Donath MY, Gross DJ, Cerasi E, Kaiser N.

Diabetes. 1999 Apr;48(4):738-44.PMID: 10102689 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes.

Nesher R, Gross DJ, Donath MY, Cerasi E, Kaiser N.

Diabetes. 1999 Apr;48(4):731-7.PMID: 10102688 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil).

Shafrir E, Ziv E, Kalman R.

ILAR J. 2006;47(3):212-24. Review.PMID: 16804196 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.

Nesher R, Warwar N, Khan A, Efendic S, Cerasi E, Kaiser N.

Diabetes. 2001 Feb;50(2):308-14.PMID: 11272141 [PubMed - indexed for MEDLINE]Related articlesFree article

IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes.

Leibowitz G, Ferber S, Apelqvist A, Edlund H, Gross DJ, Cerasi E, Melloul D, Kaiser N.

Diabetes. 2001 Aug;50(8):1799-806.PMID: 11473041 [PubMed - indexed for MEDLINE]Related articlesFree article

[Type 2 diabetes and beta cell apoptosis]

Cerasi E, Kaiser N, Leibowitz G.

Diabetes Metab. 2000 Jun;26 Suppl 3:13-6. Review. French. PMID: 10945145 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanism of nutritionally induced insulin resistance: the desert rodent Psammomys obesus and other animals in which insulin resistance leads to detrimental outcome.

Shafrir E, Ziv E.

J Basic Clin Physiol Pharmacol. 1998;9(2-4):347-85.PMID: 10212843 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion in obese and non-obese NIDDM.

Cerasi E, Nesher R, Gadot M, Gross D, Kaiser N.

Diabetes Res Clin Pract. 1995 Aug;28 Suppl:S27-37. Review.PMID: 8529516 [PubMed - indexed for MEDLINE]Related articles

Gradual loss of pancreatic beta-cell insulin, glucokinase and GLUT2 glucose transporter immunoreactivities during the time course of nutritionally induced type-2 diabetes in Psammomys obesus (sand rat).

Jörns A, Tiedge M, Ziv E, Shafrir E, Lenzen S.

Virchows Arch. 2002 Jan;440(1):63-9.PMID: 11942578 [PubMed - indexed for MEDLINE]Related articles

Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure.

Leibowitz G, Uçkaya G, Oprescu AI, Cerasi E, Gross DJ, Kaiser N.

Endocrinology. 2002 Sep;143(9):3214-20.PMID: 12193532 [PubMed - indexed for MEDLINE]Related articlesFree article

Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis.

Bar-On H, Ben-Sasson R, Ziv E, Arar N, Shafrir E.

Pancreas. 1999 Apr;18(3):259-65.PMID: 10206484 [PubMed - indexed for MEDLINE]Related articles

mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.

Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G.

Diabetes. 2008 Apr;57(4):945-57. Epub 2008 Jan 3.PMID: 18174523 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunocytochemical investigation of insulin secretion by pancreatic beta-cells in control and diabetic Psammomys obesus.

Bendayan M, Malide D, Ziv E, Levy E, Ben-Sasson R, Kalman R, Bar-On H, Chrétien M, Seidah N.

J Histochem Cytochem. 1995 Aug;43(8):771-84.PMID: 7622840 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of metabolic state in an animal model of nutrition-dependent type 2 diabetes following treatment with S 23521, a new glucagon-like peptide 1 (GLP-1) analogue.

Uçkaya G, Delagrange P, Chavanieu A, Grassy G, Berthault MF, Ktorza A, Cerasi E, Leibowitz G, Kaiser N.

J Endocrinol. 2005 Mar;184(3):505-13.PMID: 15749809 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

Pertusa JA, Nesher R, Kaiser N, Cerasi E, Henquin JC, Jonas JC.

Diabetes. 2002 Aug;51(8):2552-60.PMID: 12145170 [PubMed - indexed for MEDLINE]Related articlesFree article

Changing pattern of prevalence of insulin resistance in Psammomys obesus, a model of nutritionally induced type 2 diabetes.

Ziv E, Shafrir E, Kalman R, Galer S, Bar-On H.

Metabolism. 1999 Dec;48(12):1549-54.PMID: 10599987 [PubMed - indexed for MEDLINE]Related articles

Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the beta-cell.

Gadot M, Ariav Y, Cerasi E, Kaiser N, Gross DJ.

Endocrinology. 1995 Oct;136(10):4218-23.PMID: 7664638 [PubMed - indexed for MEDLINE]Related articles