PubMed

Tat gets the "green" light on transcription initiation.

Brady J, Kashanchi F.

Retrovirology. 2005 Nov 9;2:69. Review.PMID: 16280076 [PubMed - indexed for MEDLINE]Related articlesFree article

Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter.

Fong YW, Zhou Q.

Mol Cell Biol. 2000 Aug;20(16):5897-907.PMID: 10913173 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription.

Chen D, Fong Y, Zhou Q.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2728-33.PMID: 10077579 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs.

Raha T, Cheng SW, Green MR.

PLoS Biol. 2005 Feb;3(2):e44. Epub 2005 Feb 8.PMID: 15719058 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages.

Zhou Q, Chen D, Pierstorff E, Luo K.

EMBO J. 1998 Jul 1;17(13):3681-91.PMID: 9649438 [PubMed - indexed for MEDLINE]Related articlesFree article

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription.

Zhou M, Halanski MA, Radonovich MF, Kashanchi F, Peng J, Price DH, Brady JN.

Mol Cell Biol. 2000 Jul;20(14):5077-86.PMID: 10866664 [PubMed - indexed for MEDLINE]Related articlesFree article

Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription.

Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7791-6.PMID: 10393900 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription.

Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A.

Biochem J. 2002 Jun 15;364(Pt 3):649-57.PMID: 12049628 [PubMed - indexed for MEDLINE]Related articlesFree article

Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro.

Wang Z, Morris GF, Rice AP, Xiong W, Morris CB.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Jun 1;12(2):128-38.PMID: 8680883 [PubMed - indexed for MEDLINE]Related articles

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA.

Garber ME, Mayall TP, Suess EM, Meisenhelder J, Thompson NE, Jones KA.

Mol Cell Biol. 2000 Sep;20(18):6958-69.PMID: 10958691 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct transcriptional pathways of TAR-dependent and TAR-independent human immunodeficiency virus type-1 transactivation by Tat.

Yang L, Morris GF, Lockyer JM, Lu M, Wang Z, Morris CB.

Virology. 1997 Aug 18;235(1):48-64.PMID: 9300036 [PubMed - indexed for MEDLINE]Related articles

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences.

Bourgeois CF, Kim YK, Churcher MJ, West MJ, Karn J.

Mol Cell Biol. 2002 Feb;22(4):1079-93.PMID: 11809800 [PubMed - indexed for MEDLINE]Related articlesFree article

The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat.

Fujinaga K, Cujec TP, Peng J, Garriga J, Price DH, Graña X, Peterlin BM.

J Virol. 1998 Sep;72(9):7154-9.PMID: 9696809 [PubMed - indexed for MEDLINE]Related articlesFree article

Tackling Tat.

Karn J.

J Mol Biol. 1999 Oct 22;293(2):235-54. Review.PMID: 10550206 [PubMed - indexed for MEDLINE]Related articles

Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase.

Chen D, Zhou Q.

Mol Cell Biol. 1999 Apr;19(4):2863-71.PMID: 10082552 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for functional interaction between the HIV-1 Tat transactivator and the TATA box binding protein in vivo.

Veschambre P, Simard P, Jalinot P.

J Mol Biol. 1995 Jul 7;250(2):169-80.PMID: 7608968 [PubMed - indexed for MEDLINE]Related articles

A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat.

Brès V, Gomes N, Pickle L, Jones KA.

Genes Dev. 2005 May 15;19(10):1211-26.PMID: 15905409 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.

O'Keeffe B, Fong Y, Chen D, Zhou S, Zhou Q.

J Biol Chem. 2000 Jan 7;275(1):279-87.PMID: 10617616 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription.

Agbottah E, Deng L, Dannenberg LO, Pumfery A, Kashanchi F.

Retrovirology. 2006 Aug 7;3:48.PMID: 16893449 [PubMed - indexed for MEDLINE]Related articlesFree article

An in vitro transcription system that recapitulates equine infectious anemia virus tat-mediated inhibition of human immunodeficiency virus type 1 Tat activity demonstrates a role for positive transcription elongation factor b and associated proteins in the mechanism of Tat activation.

Suñé C, Goldstrohm AC, Peng J, Price DH, Garcia-Blanco MA.

Virology. 2000 Sep 1;274(2):356-66.PMID: 10964778 [PubMed - indexed for MEDLINE]Related articles